第14回カテコールアミンと循環器系研究会 イヌ摘出心臓標本における徐脈薬UL-FS49と各種強心薬の相互作用
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| Published in | 心臓 Vol. 25; no. Supplement3; pp. 25 - 27 |
|---|---|
| Main Authors | , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
公益財団法人 日本心臓財団
1993
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| Online Access | Get full text |
| ISSN | 0586-4488 2186-3016 |
| DOI | 10.11281/shinzo1969.25.Supplement3_25 |
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| Author | 千葉, 茂俊 澤木, 章二 古川, 安之 |
|---|---|
| Author_xml | – sequence: 1 fullname: 千葉, 茂俊 organization: 信州大学医学部薬理学教室 – sequence: 1 fullname: 澤木, 章二 organization: 信州大学医学部薬理学教室 – sequence: 1 fullname: 古川, 安之 organization: 信州大学医学部薬理学教室 |
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| References | 12) Yang T, Tande PM and Refsum H: Negative chronotropic effect of a novel class III antiarrhythmic drug, UK-68, 798, devoid of β-blocking action on isolated guinea-pig atria. Br J Pharmacol 103: 1417, 1991 4) Van Bogaert PP, Goethals M and Simoens C: Use- and frequency-dependent blockade by UL -FS 49 of the I pacemaker current in sheep cardiac Purkinje fibers. Eur J Pharmacol 187: 241, 1990 11) Furukawa Y, Takayama S, Sawaki S, et al: A bradycardic agent, UL-FS 49 increases atrial force and decreases ventricular force in isolated, perfused heart preparations of dogs. J Pharmacol Exp Ther 265: 801, 1993 8) Brown HF, DiFrancesco D and Noble SJ: How does adrenaline accelerate the heart ? Nature 280: 235, 1979 7) Furukawa Y, Ogiwara Y, Akahane K, et al: Different antagonism of the positive chronotropic and inotropic response of the isolated, blood-perfused dog atrium to Bay k 8644 by nicardipine and verapamil. Eur J Pharmacol 156: 231, 1988 9) DiFrancesco D and Tortora P: Direct activation of cardiac pacemaker channels by intracellular cyclic AMP. Nature 351: 145, 1991 6) Chiba S, Kimura T and Hashimoto K: Muscarinic suppression of the nicotinic action of acetylcholine on the isolated, blood-perfused atrium of the dog. Naunyn-Schmiedeberg's Arch Pharmacol 289: 315, 1975 3) Lillie C and Kobinger W: Investigation into the bradycardic effects of UL-FS 49(1, 3, 4, 5-tetrahydro -7, 8-dimethoxy -3- [3- [ [2- (3, 4-dimethoxyphenyl) ethyl] methylimino] propyl] -2 H -3 - benzazepin -2-on-hydrochloride) in isolated guinea pig atria. J Cardiovasc Pharmacol 8: 791, 1986 1) Kobinger W and Lillie C: Cardiovascular characterization of UL-FS 49, 1, 3, 4, 5-tetrahydro-7, 8-dimethoxy -3- [3- [ [2- (3, 4 -dimethoxyphenyl) ethyl] methylimino] propyl] -2 H -3-benzazepin-2-on-hydrochloride, a new“specific bradycardic agent”. Eur J Pharmacol 104: 9, 1984 13) Noma A, Kotake H and Irisawa H: Slow inward current and its role mediating the chronotropic effect of epinephrine in the rabbit sinoatrial node. Pflugers Arch 388 1, 1980 5) Doerr TH and Trautwein w: On the mechanism of the“specific bradycardic action”of the verapamil derivative UL - FS 49. Naunyn - Schmiedeberg's Arch Pharmacol 341: 331, 1990 2) Kobinger W and Lillie C: Falipamil (AQ-A 39) and UL-FS 49. Cardiovasc Drug Rev 6: 35, 1988 10) DiFrancesco D: The cardiac hyperpolarizingactivated current, If origin and developments. Prog Biophys Molec Biol 46: 163, 1985 |
| References_xml | – reference: 12) Yang T, Tande PM and Refsum H: Negative chronotropic effect of a novel class III antiarrhythmic drug, UK-68, 798, devoid of β-blocking action on isolated guinea-pig atria. Br J Pharmacol 103: 1417, 1991 – reference: 5) Doerr TH and Trautwein w: On the mechanism of the“specific bradycardic action”of the verapamil derivative UL - FS 49. Naunyn - Schmiedeberg's Arch Pharmacol 341: 331, 1990 – reference: 13) Noma A, Kotake H and Irisawa H: Slow inward current and its role mediating the chronotropic effect of epinephrine in the rabbit sinoatrial node. Pflugers Arch 388 1, 1980 – reference: 10) DiFrancesco D: The cardiac hyperpolarizingactivated current, If origin and developments. Prog Biophys Molec Biol 46: 163, 1985 – reference: 1) Kobinger W and Lillie C: Cardiovascular characterization of UL-FS 49, 1, 3, 4, 5-tetrahydro-7, 8-dimethoxy -3- [3- [ [2- (3, 4 -dimethoxyphenyl) ethyl] methylimino] propyl] -2 H -3-benzazepin-2-on-hydrochloride, a new“specific bradycardic agent”. Eur J Pharmacol 104: 9, 1984 – reference: 7) Furukawa Y, Ogiwara Y, Akahane K, et al: Different antagonism of the positive chronotropic and inotropic response of the isolated, blood-perfused dog atrium to Bay k 8644 by nicardipine and verapamil. Eur J Pharmacol 156: 231, 1988 – reference: 9) DiFrancesco D and Tortora P: Direct activation of cardiac pacemaker channels by intracellular cyclic AMP. Nature 351: 145, 1991 – reference: 8) Brown HF, DiFrancesco D and Noble SJ: How does adrenaline accelerate the heart ? Nature 280: 235, 1979 – reference: 11) Furukawa Y, Takayama S, Sawaki S, et al: A bradycardic agent, UL-FS 49 increases atrial force and decreases ventricular force in isolated, perfused heart preparations of dogs. J Pharmacol Exp Ther 265: 801, 1993 – reference: 3) Lillie C and Kobinger W: Investigation into the bradycardic effects of UL-FS 49(1, 3, 4, 5-tetrahydro -7, 8-dimethoxy -3- [3- [ [2- (3, 4-dimethoxyphenyl) ethyl] methylimino] propyl] -2 H -3 - benzazepin -2-on-hydrochloride) in isolated guinea pig atria. J Cardiovasc Pharmacol 8: 791, 1986 – reference: 4) Van Bogaert PP, Goethals M and Simoens C: Use- and frequency-dependent blockade by UL -FS 49 of the I pacemaker current in sheep cardiac Purkinje fibers. Eur J Pharmacol 187: 241, 1990 – reference: 6) Chiba S, Kimura T and Hashimoto K: Muscarinic suppression of the nicotinic action of acetylcholine on the isolated, blood-perfused atrium of the dog. Naunyn-Schmiedeberg's Arch Pharmacol 289: 315, 1975 – reference: 2) Kobinger W and Lillie C: Falipamil (AQ-A 39) and UL-FS 49. Cardiovasc Drug Rev 6: 35, 1988 |
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| Title | 第14回カテコールアミンと循環器系研究会 イヌ摘出心臓標本における徐脈薬UL-FS49と各種強心薬の相互作用 |
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