プロベネシドが3次元培養された前立腺がん細胞に与える多様な効果

• Published in: 日本薬理学会年会要旨集 p. 1-B-P-078
• Main Authors: 宇和田, 淳介, 中澤, 瞳, 益岡, 尚由
• Format: Journal Article
• Language: Japanese
• Published: 公益社団法人 日本薬理学会 2022
• Subjects: cancer; chemotherapy; transporter; uricosuric agent

Probenecid, an uricosuric drug, has diverse pharmacological targets, including multidrug resistance-associated protein (MRP). Since inhibition of MRPs contributes to suppression of efflux of anti-cancer drugs, probenecid has been investigated for cancer therapy as a chemosensitizer. In this study, w...