B-cell acute lymphoblastic leukemia developed 5 years after autologous stem cell transplantation for multiple myeloma

• Published in: Rinshō ketsueki Vol. 53; no. 2; p. 219
• Main Authors: Tsukada, Yuiko, Hattori, Yutaka, Nakajima, Hideaki, Yokoyama, Kenji, Murata, Mitsuru, Shimizu, Nobuko, Kondo, Naomi, Okamoto, Shinichiro
• Format: Journal Article
• Language: Japanese
• Published: Japan 01.02.2012
• Subjects: Female; Gene Rearrangement - genetics; Hematopoietic Stem Cell Transplantation; Humans; Immunoglobulin Heavy Chains - genetics; Leukemia, B-Cell - diagnosis; Leukemia, B-Cell - etiology; Leukemia, B-Cell - genetics; Middle Aged; Multiple Myeloma - therapy; Precursor Cell Lymphoblastic Leukemia-Lymphoma - diagnosis; Precursor Cell Lymphoblastic Leukemia-Lymphoma - etiology; Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics; Time Factors; Transplantation, Autologous

A 61-year-old female was diagnosed with multiple myeloma (MM) in 2001. After treatment with chemotherapy containing alkylating agents and thalidomide, she underwent autologous stem cell transplantation in 2003, with high-dose melphalan as a conditioning regimen. Thalidomide was also given after the...