マウスⅠ型糖尿病誘発アロディニアにおける脊髄cholecystokinin-8とhemokinin-1の関与

• Published in: 日本薬理学会年会要旨集 p. 3-P1-05
• Main Authors: 林, 貴史, 渡辺, 千寿子, 菅野, 秀一, 善積, 克, 我妻, 恭行, 原, 明義, 櫻田, 忍
• Format: Journal Article
• Language: Japanese
• Published: 公益社団法人 日本薬理学会 2021
• Subjects: cholecystokinin; neurotransmitter; nociception; spinal cord

Diabetes mellitus is one of the major causes of peripheral neuropathy which represented by the mechanical allodynia. The mechanical allodynia has been suggested to involve several pain-related neurotransmitters in the dorsal spinal cord. The sulfated octapeptide cholecystokinin (CCK-8) is present in...