加速度誘発性意識消失（Gravity-induced loss of consciousness：G-LOC）予測式作成の試み

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Published in航空医学実験隊報告 Vol. 57; no. 2; pp. 15 - 26
Main Authors 大類, 伸浩, 菊川, あずさ, 荒毛, 将史, 蔵本, 浩一郎, 髙田, 邦夫, 別宮, 愼也, 小林, 朝夫, 山口, 大介, 溝端, 裕亮, 藤田, 真敬
Format Journal Article
LanguageJapanese
Published 航空医学実験隊 2017
Online AccessGet full text
ISSN0023-2858
2432-4809
DOI10.20846/jasdfaml.57.2_15

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Author 溝端, 裕亮
蔵本, 浩一郎
山口, 大介
髙田, 邦夫
菊川, あずさ
別宮, 愼也
大類, 伸浩
藤田, 真敬
小林, 朝夫
荒毛, 将史
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  organization: 航空自衛隊 航空医学実験隊
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  organization: 航空自衛隊 航空医学実験隊
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  fullname: 山口, 大介
  organization: 航空自衛隊 航空医学実験隊
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  fullname: 溝端, 裕亮
  organization: 航空自衛隊 航空医学実験隊
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  fullname: 藤田, 真敬
  organization: 防衛医科大学校 防衛医学研究センター 異常環境衛生研究部門
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References 19) Tripp LD, Warm JS, Matthews G, Chiu PY, Bracken RB. On tracking the course of cerebral oxygen saturation and pilot performance during gravity-induced loss of consciousness. Hum Factors. 2009; 51(6):775–784.
36) 石黒勝彦, 竹内　孝. 特徴的な構造を抽出するデータマイニング技術. NTT技術ジャーナル. 2012; 9:14–18. http://www.ntt.co.jp/journal/1209/files/jn201209014.pdf（参照 2016-11-11）.
5) Yilmaz U, Cetinguc M, Akin A. Visual symptoms and G-LOC in the operational environment and during centrifuge training of Turkish jet pilots. Aviat Space Environ Med. 1999; 70(7):709–712.
35) Albery WB, Khomenko MN. Differences in pilot automation philosophies in the US and Russian Air Forces ground collision avoidance systems. Wright-Patterson AFB (OH): Air Force Research Lab, RF DM State Scientific Research Testing Institute of Military Medicine; 2003 Oct. No.:RTO-MP-088. http://www.dtic.mil/dtic/tr/fulltext/u2/a422250.pdf （accessed 2016-11-11）.
7) Green ND, Ford SA. G-induced loss of consciousness: retrospective survey results from 2259 military aircrew. Aviat Space Environ Med. 2006; 77(6):619–623.
13) 黒田泰弘. 神経集中治療のピットフォール: 近赤外線分光法による脳酸素飽和度モニタリング. 日集中医誌. 2015; 22(1):3–8.
14) 高梨吉則. Near-infrared spectroscopyと体外循環中の脳酸素代謝モニタリング. 日小循環器会誌. 2004; 20(6):618–619.
37) 上田修功. ビッグデータを活かす機械学習技術. NTT技術ジャーナル. 2013; 4:31–35. http://www.ntt.co.jp/journal/1304/files/jn201304031.pdf （参照 2016-11-11）.
20) Webb JT, Oakley CJ, Meeker LJ. Unpredictability of fighter pilot G tolerance using anthropometric and physiologic variables. Aviat Space Environ Med. 1991; 62(2):128–135.
4) Alvim KM. Greyout, blackout, and G-loss of consciousness in the Brazilian Air Force: a 1991–92 survey. Aviat Space Environ Med. 1995; 66(7):675–677.
2) Lyons TJ, Kraft NO, Copley GB, Davenport C, Grayson K, Binder H. Analysis of mission and aircraft factors in G-induced loss of consciousness in the USAF: 1982–2002. Aviat Space Environ Med. 2004; 75(6):479–482.
10) Kobayashi A, Kikukawa A, Onozawa A. Effect of muscle tensing on cerebral oxygen status during sustained high +Gz. Aviat Space Environ Med. 2002; 73(6):597–600.
11) Kurihara K, Kikukawa A, Kobayashi A, Nakadate T. Frontal cortical oxygenation changes during gravity-induced loss of consciousness in humans: a near-infrared spatially resolved spectroscopic study. J Appl Physiol. 2007; 103(4):1326–1331.
12) Kobayashi A, Kikukawa A, Kimura M, Inui T, Miyamoto Y. Cerebral near-infrared spectroscopy to evaluate anti-G straining maneuvers in centrifuge training. Aviat Space Environ Med. 2012; 83(8):790–794.
18) Wilson GF, Reis GA, Tripp LD. EEG correlates of G-induced loss of consciousness. Aviat Space Environ Med. 2005; 76(1):19–27.
21) Framingham, Massachusetts, USA. Framingham Heart Study. A project of the national heart, lung, and blood institute and Boston university. http://www.framinghamheartstudy.org/index.php （accessed 2016-11-11）.
30) Suzuki S, Takasaki S, Ozaki T, Kobayashi Y. Tissue oxygenation monitor using NIR spatially resolved spectroscopy. In: Chance B, Alfano RR, Tromberg BJ. BiOS'99 International Biomedical Optics Symposium, International Society for Optics and Photonics; January 23; San Jose(CA), USA. Bellingham(WA): SPIE; 1999. 3597:582–592.
32) 河野寛幸. 失神・失神性めまい１ 病態と言葉の説明. アメリカ心臓協会 BLS, ACLS講習会. http://emergency-room.jp/syncope-and-fainting001/ （参照 2016-11-11）.
6) Rickards CA, Newman DG. G-induced visual and cognitive disturbances in a survey of 65 operational fighter pilots. Aviat Space Environ Med. 2005; 76(5):496–500.
25) Katz ML, Comerota AJ, Kerr R. Air plethysmography (APG): a new technique to evaluate patients with chronic venous insufficiency. J Vasc Tech. 1991; 15(1):23–27.
33) 杉本　侃. 出血性ショックと細菌性ショック 1. 出血性ショック. 日臨外医会誌. 1976; 37(2): 107–109.
16) Borchardt CJ. Cerebral oxygen saturation as a predictor of impending gravity induced loss of consciousness (GLOC) [Master's thesis]. Houston (TX): Texas univ health science center at Houston; 2003.
9) 宮本吉教, 小林朝夫, 菊川あずさ. 航空医学実験隊における近赤外分光法による脳内酸素状態の研究について. 航空医実験隊報. 2006; 46(3):33–42.
3) Johanson DC, Pheeny HT. A new look at the loss of consciousness experience within the U.S. Naval forces. Aviat Space Environ Med. 1988; 59(1):6–8.
29) Jöbsis FF. Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters. Science. 1977; 198(4323):1264–1267.
17) Ryoo HC, Sun HH, Shender BS, Hrebien L. Consciousness monitoring using near-infrared spectroscopy (NIRS) during high+ Gz exposures. Med Eng Phys. 2004; 26(9):745–753.
34) Albery WB, Van Patten RE. Non-invasive sensing systems for acceleration-induced physiologic changes. IEEE Eng Med Biol Mag. 1991; 10(1):46–51.
23) 中澤秀夫. ロジスティック回帰. 日医大医会誌 2014; 10(4):186–191.
28) 丸山　聡, 竹内　誠. 航空機と加速度（G）. In: 藤田真敬 監修. 宇宙航空医学入門. 東京: 鳳文書林出版; 2015, p.96–110.
24) Fortin J, Habenbacher W, Heller A, Hacker A, Grüllenberger R, Innerhofer J, et al. Non-invasive beat-to-beat cardiac output monitoring by an improved method of transthoracic bioimpedance measurement. Comput Biol Med. 2006; 36(11):1185–1203.
26) 大類伸浩, 藤田真敬, 菊川あずさ, 蔵本浩一郎, 小林朝夫, 溝端裕亮, 立花正一, et al. 加速度誘発性意識消失（Gravity - induced Loss of Consciousness: G-LOC）の評価と対策. 航空医実験隊報. 2016; 56(3):43–66.
1) Woodrow AD, Shaffstall RM, Albery WB. Physiologic Effects of Acceleration. In: Woodrow AD (SpecPro Inc. and Eagle Applied Sciences, LLC, San Antonio, TX), Webb JT (SpecPro Inc. and Eagle Applied Sciences, LLC, San Antonio, TX). Handbook of Aerospace and Operational Physiology. Final report. Wright-Patterson AFB (OH): USAF School of Aerospace Medicine Aerospace Medicine Education, Training Division (FEEP); 2011 July. Report No.: AFRL-SA-WP-SR-2011-0003. Contract No.: FA 8901-04-D-0004 Task 0057 and FA 8900-07-D-0001 Task 0001 and Task 0061 and FA 8900-09-D-0001 Task 0008. Woodrow AD, Webb JT. Handbook of Aerospace and Operational Physiology. Specpro Inc San Antonio TX, 2011; p.7-1 – 7-20. http://www.dtic.mil/dtic/tr/fulltext/u2/a548404.pdf （accessed 2016-11-11）.
15) Shender BS, Forster EM, Hrebien L, Ryoo HC, Cammarota JP. Acceleration-induced near-loss of consciousness: the “A-LOC” syndrome. Aviat Space Environ Med. 2003; 74(10):1021–1028.
27) 航空自衛隊航空幕僚長通達・耐G訓練の実施要領について, 空幕衛第165号例規（平成14 年7 月10 日）.
31) 小川　渉, 宮崎　滋. 肥満と肥満症の診断基準. 総合健診. 2015; 42(2):301–306.
8) Cao XS, Wang YC, Xu L, Yang CB, Wang B, Geng J, Gao Y, Wu YH, Wang XY, Zhang S, Sun XQ. Visual symptoms and G-induced loss of consciousness in 594 Chinese Air Force aircrew—a questionnaire survey. Mil Med. 2012; 177(2):163–168.
22) 佐藤俊哉. 疫学研究における生物統計手法. 日本統計学会誌. 1993; 22(3):493–513.
References_xml – reference: 21) Framingham, Massachusetts, USA. Framingham Heart Study. A project of the national heart, lung, and blood institute and Boston university. http://www.framinghamheartstudy.org/index.php （accessed 2016-11-11）.
– reference: 17) Ryoo HC, Sun HH, Shender BS, Hrebien L. Consciousness monitoring using near-infrared spectroscopy (NIRS) during high+ Gz exposures. Med Eng Phys. 2004; 26(9):745–753.
– reference: 19) Tripp LD, Warm JS, Matthews G, Chiu PY, Bracken RB. On tracking the course of cerebral oxygen saturation and pilot performance during gravity-induced loss of consciousness. Hum Factors. 2009; 51(6):775–784.
– reference: 20) Webb JT, Oakley CJ, Meeker LJ. Unpredictability of fighter pilot G tolerance using anthropometric and physiologic variables. Aviat Space Environ Med. 1991; 62(2):128–135.
– reference: 31) 小川　渉, 宮崎　滋. 肥満と肥満症の診断基準. 総合健診. 2015; 42(2):301–306.
– reference: 22) 佐藤俊哉. 疫学研究における生物統計手法. 日本統計学会誌. 1993; 22(3):493–513.
– reference: 33) 杉本　侃. 出血性ショックと細菌性ショック 1. 出血性ショック. 日臨外医会誌. 1976; 37(2): 107–109.
– reference: 3) Johanson DC, Pheeny HT. A new look at the loss of consciousness experience within the U.S. Naval forces. Aviat Space Environ Med. 1988; 59(1):6–8.
– reference: 28) 丸山　聡, 竹内　誠. 航空機と加速度（G）. In: 藤田真敬 監修. 宇宙航空医学入門. 東京: 鳳文書林出版; 2015, p.96–110.
– reference: 11) Kurihara K, Kikukawa A, Kobayashi A, Nakadate T. Frontal cortical oxygenation changes during gravity-induced loss of consciousness in humans: a near-infrared spatially resolved spectroscopic study. J Appl Physiol. 2007; 103(4):1326–1331.
– reference: 27) 航空自衛隊航空幕僚長通達・耐G訓練の実施要領について, 空幕衛第165号例規（平成14 年7 月10 日）.
– reference: 5) Yilmaz U, Cetinguc M, Akin A. Visual symptoms and G-LOC in the operational environment and during centrifuge training of Turkish jet pilots. Aviat Space Environ Med. 1999; 70(7):709–712.
– reference: 37) 上田修功. ビッグデータを活かす機械学習技術. NTT技術ジャーナル. 2013; 4:31–35. http://www.ntt.co.jp/journal/1304/files/jn201304031.pdf （参照 2016-11-11）.
– reference: 25) Katz ML, Comerota AJ, Kerr R. Air plethysmography (APG): a new technique to evaluate patients with chronic venous insufficiency. J Vasc Tech. 1991; 15(1):23–27.
– reference: 12) Kobayashi A, Kikukawa A, Kimura M, Inui T, Miyamoto Y. Cerebral near-infrared spectroscopy to evaluate anti-G straining maneuvers in centrifuge training. Aviat Space Environ Med. 2012; 83(8):790–794.
– reference: 13) 黒田泰弘. 神経集中治療のピットフォール: 近赤外線分光法による脳酸素飽和度モニタリング. 日集中医誌. 2015; 22(1):3–8.
– reference: 14) 高梨吉則. Near-infrared spectroscopyと体外循環中の脳酸素代謝モニタリング. 日小循環器会誌. 2004; 20(6):618–619.
– reference: 8) Cao XS, Wang YC, Xu L, Yang CB, Wang B, Geng J, Gao Y, Wu YH, Wang XY, Zhang S, Sun XQ. Visual symptoms and G-induced loss of consciousness in 594 Chinese Air Force aircrew—a questionnaire survey. Mil Med. 2012; 177(2):163–168.
– reference: 16) Borchardt CJ. Cerebral oxygen saturation as a predictor of impending gravity induced loss of consciousness (GLOC) [Master's thesis]. Houston (TX): Texas univ health science center at Houston; 2003.
– reference: 30) Suzuki S, Takasaki S, Ozaki T, Kobayashi Y. Tissue oxygenation monitor using NIR spatially resolved spectroscopy. In: Chance B, Alfano RR, Tromberg BJ. BiOS'99 International Biomedical Optics Symposium, International Society for Optics and Photonics; January 23; San Jose(CA), USA. Bellingham(WA): SPIE; 1999. 3597:582–592.
– reference: 10) Kobayashi A, Kikukawa A, Onozawa A. Effect of muscle tensing on cerebral oxygen status during sustained high +Gz. Aviat Space Environ Med. 2002; 73(6):597–600.
– reference: 6) Rickards CA, Newman DG. G-induced visual and cognitive disturbances in a survey of 65 operational fighter pilots. Aviat Space Environ Med. 2005; 76(5):496–500.
– reference: 24) Fortin J, Habenbacher W, Heller A, Hacker A, Grüllenberger R, Innerhofer J, et al. Non-invasive beat-to-beat cardiac output monitoring by an improved method of transthoracic bioimpedance measurement. Comput Biol Med. 2006; 36(11):1185–1203.
– reference: 35) Albery WB, Khomenko MN. Differences in pilot automation philosophies in the US and Russian Air Forces ground collision avoidance systems. Wright-Patterson AFB (OH): Air Force Research Lab, RF DM State Scientific Research Testing Institute of Military Medicine; 2003 Oct. No.:RTO-MP-088. http://www.dtic.mil/dtic/tr/fulltext/u2/a422250.pdf （accessed 2016-11-11）.
– reference: 15) Shender BS, Forster EM, Hrebien L, Ryoo HC, Cammarota JP. Acceleration-induced near-loss of consciousness: the “A-LOC” syndrome. Aviat Space Environ Med. 2003; 74(10):1021–1028.
– reference: 23) 中澤秀夫. ロジスティック回帰. 日医大医会誌 2014; 10(4):186–191.
– reference: 34) Albery WB, Van Patten RE. Non-invasive sensing systems for acceleration-induced physiologic changes. IEEE Eng Med Biol Mag. 1991; 10(1):46–51.
– reference: 36) 石黒勝彦, 竹内　孝. 特徴的な構造を抽出するデータマイニング技術. NTT技術ジャーナル. 2012; 9:14–18. http://www.ntt.co.jp/journal/1209/files/jn201209014.pdf（参照 2016-11-11）.
– reference: 1) Woodrow AD, Shaffstall RM, Albery WB. Physiologic Effects of Acceleration. In: Woodrow AD (SpecPro Inc. and Eagle Applied Sciences, LLC, San Antonio, TX), Webb JT (SpecPro Inc. and Eagle Applied Sciences, LLC, San Antonio, TX). Handbook of Aerospace and Operational Physiology. Final report. Wright-Patterson AFB (OH): USAF School of Aerospace Medicine Aerospace Medicine Education, Training Division (FEEP); 2011 July. Report No.: AFRL-SA-WP-SR-2011-0003. Contract No.: FA 8901-04-D-0004 Task 0057 and FA 8900-07-D-0001 Task 0001 and Task 0061 and FA 8900-09-D-0001 Task 0008. Woodrow AD, Webb JT. Handbook of Aerospace and Operational Physiology. Specpro Inc San Antonio TX, 2011; p.7-1 – 7-20. http://www.dtic.mil/dtic/tr/fulltext/u2/a548404.pdf （accessed 2016-11-11）.
– reference: 2) Lyons TJ, Kraft NO, Copley GB, Davenport C, Grayson K, Binder H. Analysis of mission and aircraft factors in G-induced loss of consciousness in the USAF: 1982–2002. Aviat Space Environ Med. 2004; 75(6):479–482.
– reference: 7) Green ND, Ford SA. G-induced loss of consciousness: retrospective survey results from 2259 military aircrew. Aviat Space Environ Med. 2006; 77(6):619–623.
– reference: 9) 宮本吉教, 小林朝夫, 菊川あずさ. 航空医学実験隊における近赤外分光法による脳内酸素状態の研究について. 航空医実験隊報. 2006; 46(3):33–42.
– reference: 26) 大類伸浩, 藤田真敬, 菊川あずさ, 蔵本浩一郎, 小林朝夫, 溝端裕亮, 立花正一, et al. 加速度誘発性意識消失（Gravity - induced Loss of Consciousness: G-LOC）の評価と対策. 航空医実験隊報. 2016; 56(3):43–66.
– reference: 29) Jöbsis FF. Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters. Science. 1977; 198(4323):1264–1267.
– reference: 32) 河野寛幸. 失神・失神性めまい１ 病態と言葉の説明. アメリカ心臓協会 BLS, ACLS講習会. http://emergency-room.jp/syncope-and-fainting001/ （参照 2016-11-11）.
– reference: 4) Alvim KM. Greyout, blackout, and G-loss of consciousness in the Brazilian Air Force: a 1991–92 survey. Aviat Space Environ Med. 1995; 66(7):675–677.
– reference: 18) Wilson GF, Reis GA, Tripp LD. EEG correlates of G-induced loss of consciousness. Aviat Space Environ Med. 2005; 76(1):19–27.
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Title 加速度誘発性意識消失（Gravity-induced loss of consciousness：G-LOC）予測式作成の試み
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ispartofPNX 航空医学実験隊報告, 2017, Vol.57(2), pp.15-26
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