The role of monocyte chemotactic and activating factor (MCAF)/monocyte chemoattractant protein (MCP) -1 in subgroups of rapidly progressive glomerulonephritis

• Published in: Nihon Jinzo Gakkai shi Vol. 41; no. 7; pp. 704 - 711
• Main Authors: SAKAI, Norihiko, WADA, Takashi, FURUICHI, Kengo, TAKAEDA, Chikako, SHIMIZU, Miho, IWATA, Yasunori, YOSHIMOTO, Kei-ichi, SHIMIZU, Kazuaki, KOBAYASHI, Ken-ichi, TAKEDA, Shin-ichi, KIDA, Hiroshi, MUKAIDA, Naofumi, MATSUSHIMA, Kouji, YOKOYAMA, Hitoshi
• Format: Journal Article
• Language: Japanese
• Published: Japan Japanese Society of Nephrology 01.10.1999
• Subjects: Anti-Inflammatory Agents - administration & dosage; Biomarkers - analysis; Chemokine CCL2 - analysis; Chemokine CCL2 - physiology; Chemokine CCL2 - urine; Disease Progression; Female; Glomerulonephritis - classification; Glomerulonephritis - drug therapy; Glomerulonephritis - etiology; Humans; Kidney - metabolism; Male; MCAF/MCP-1, chemokine, rapidly progressive glomerulonephritis, crescentic glomerulone phritis; Methylprednisolone - administration & dosage; Middle Aged

To elucidate the role of monocyte chemotactic and activating factor (MCAF)/monocytechemoattractant protein (MCP) -1 in the pathogenesis of rapidly progressive glomerulonephritis (RPGN), we determined the urinary levels of MCAF/MCP-1 in 20 healthy subjects, 30 patients showing RPGN with crescents, an...