脳由来神経栄養因子（BDNF）を用いた新しい歯周炎治療の開発
Saved in:
| Published in | 日本歯周病学会会誌 Vol. 58; no. 3; pp. 91 - 97 |
|---|---|
| Main Authors | , , , , , , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
特定非営利活動法人 日本歯周病学会
2016
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 0385-0110 1880-408X |
| DOI | 10.2329/perio.58.91 |
Cover
Loading…
| Author | 佐々木, 慎也 水野, 智仁 藤田, 剛 栗原, 英見 武田, 克浩 加治屋, 幹人 柏井, 桂 松田, 真司 |
|---|---|
| Author_xml | – sequence: 1 fullname: 加治屋, 幹人 organization: 広島大学大学院医歯薬保健学研究院応用生命科学部門歯周病態学研究室 – sequence: 1 fullname: 柏井, 桂 organization: 広島大学大学院医歯薬保健学研究院応用生命科学部門歯周病態学研究室 – sequence: 1 fullname: 松田, 真司 organization: 広島大学大学院医歯薬保健学研究院応用生命科学部門歯周病態学研究室 – sequence: 1 fullname: 水野, 智仁 organization: 広島大学大学院医歯薬保健学研究院応用生命科学部門歯周病態学研究室 – sequence: 1 fullname: 藤田, 剛 organization: 広島大学大学院医歯薬保健学研究院応用生命科学部門歯周病態学研究室 – sequence: 1 fullname: 栗原, 英見 organization: 広島大学大学院医歯薬保健学研究院応用生命科学部門歯周病態学研究室 – sequence: 1 fullname: 武田, 克浩 organization: 広島大学大学院医歯薬保健学研究院応用生命科学部門歯周病態学研究室 – sequence: 1 fullname: 佐々木, 慎也 organization: 広島大学大学院医歯薬保健学研究院応用生命科学部門歯周病態学研究室 |
| BookMark | eNo9UE1LAkEAHcIgM0_9jrX52HVmLkFZViAF4aHbMjvO1oqp7HrpuOKhL6JCDInKQ4IX-6RL-W8Wd_PkX0gpurwP3uMd3jyIlStlBcAigilMMF-qKteppAyW4mgGxBFjUNMh24uBOCTM0CBCcA4kPc-xIISMYkh4HOx-N96j5mt4142699HHedhpjB5Ph7edYf9yPDheXdvOjgcnQf06avYCvxH4D2HrJfBvJjrsPw-velH9Inz7itr1wH8atc6i9ucCmLVFyVPJP06AfHY9n9nUcjsbW5mVnFZElAmNEqQowhJSiwtOlBSSp3Uq0wVdhwa3laWY5NSadDGhQgplGwbWsUQFhTEjCbD8O1v0amJfmVXXORTukSncmiNLEz-9wzSYSabA0X8gD4RrFgX5ATDueOc |
| ContentType | Journal Article |
| Copyright | 2016 特定非営利活動法人 日本歯周病学会 |
| Copyright_xml | – notice: 2016 特定非営利活動法人 日本歯周病学会 |
| DOI | 10.2329/perio.58.91 |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Dentistry |
| EISSN | 1880-408X |
| EndPage | 97 |
| ExternalDocumentID | article_perio_58_3_58_91_article_char_ja |
| GroupedDBID | 123 2WC ABJNI ALMA_UNASSIGNED_HOLDINGS CS3 F5P JSF KQ8 MOJWN OK1 RJT |
| ID | FETCH-LOGICAL-j178a-731e712c07b9a93ecac9647c6d44059febe8c97b78a237acaef55242c1de2283 |
| ISSN | 0385-0110 |
| IngestDate | Wed Sep 03 06:30:10 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 3 |
| Language | Japanese |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-j178a-731e712c07b9a93ecac9647c6d44059febe8c97b78a237acaef55242c1de2283 |
| OpenAccessLink | https://www.jstage.jst.go.jp/article/perio/58/3/58_91/_article/-char/ja |
| PageCount | 7 |
| ParticipantIDs | jstage_primary_article_perio_58_3_58_91_article_char_ja |
| PublicationCentury | 2000 |
| PublicationDate | 2016 |
| PublicationDateYYYYMMDD | 2016-01-01 |
| PublicationDate_xml | – year: 2016 text: 2016 |
| PublicationDecade | 2010 |
| PublicationTitle | 日本歯周病学会会誌 |
| PublicationTitleAlternate | 日歯周誌 |
| PublicationYear | 2016 |
| Publisher | 特定非営利活動法人 日本歯周病学会 |
| Publisher_xml | – name: 特定非営利活動法人 日本歯周病学会 |
| References | 27) Mitsui Y, Gotoh M, Nakama K, Yamada T, Higuchi F, Nagata K: Hyaluronic acid inhibits mRNA expression of proinflammatory cytokines and cyclooxygenase-2/prostaglandin E (2) production via CD44 in interleukin-1-stimulated subacromial synovial fibroblasts from patients with rotator cuff disease. J Orthop Res, 26: 1032, 2008. 2) Barrett GL: The p75 neurotrophin receptor and neuronal apoptosis. Prog Neurobiol, 61: 205, 2000. 20) Kurihara H, Shinohara H, Yoshino H, Takeda K, Shiba H: Neurotrophins in cultured cells from periodontal tissues. J Periodontol, 74: 76, 2003. 14) Erickson KI, Miller DL, Roecklein KA: The aging hippocampus: interactions between exercise, depression, and BDNF. Neuroscientist, 18: 82, 2012. 30) Jimbo R, Tovar N, Janal MN, Mousa R, Marin C, Yoo D, Teixeira HS, Anchieta RB, Bonfante EA, Konishi A, Takeda K, Kurihara H, Coelho PG: The effect of brain-derived neurotrophic factor on periodontal furcation defects. PLoS One, 9: e84845, 2014. 10) Asaumi K, Nakanishi T, Asahara H, Inoue H, Takigawa M: Expression of neurotrophins and their receptors (TRK) during fracture healing. Bone, 26: 625, 2000. 22) Kashiwai K, Kajiya M, Matsuda S, Ouhara K, Takeda K, Takata T, Kitagawa M, Fujita T, Shiba H, Kurihara H: Distinction Between Cell Proliferation and Apoptosis Signals Regulated by Brain-Derived Neurotrophic Factor in Human Periodontal Ligament Cells and Gingival Epithelial Cells. J Cell Biochem, 2015. 19) Nonomura T, Tsuchida A, Ono-Kishino M, Nakagawa T, Taiji M, Noguchi H: Brain-derived neurotrophic factor regulates energy expenditure through the central nervous system in obese diabetic mice. Int J Exp Diabetes Res, 2: 201, 2001. 23) Matsuda S, Fujita T, Kajiya M, Takeda K, Shiba H, Kawaguchi H, Kurihara H: Brain-derived neurotrophic factor induces migration of endothelial cells through a TrkB-ERK-integrin alphaVbeta3-FAK cascade. J Cell Physiol, 227: 2123, 2012. 26) Takeda K, Obinata Y, Konishi A, Kajiya M, Matsuda S, Mizuno N, Sasaki S, Fujita T, Kurihara H: Brain-Derived Neurotrophic Factor Inhibits Intercellular Adhesion Molecule-1 Expression in Interleukin-1beta-Treated Endothelial Cells. Cell Biochem Biophys, 2016. 7) Nakanishi T, Takahashi K, Aoki C, Nishikawa K, Hattori T, Taniguchi S: Expression of nerve growth factor family neurotrophins in a mouse osteoblastic cell line. Biochem Biophys Res Commun, 198: 891, 1994. 1) Barbacid M: The Trk family of neurotrophin receptors. J Neurobiol, 25: 1386, 1994. 13) Tanila H: The role of BDNF in Alzheimer's disease. Neurobiol Dis, 2016. 29) Konishi A, Takeda K, Fujita T, Kajiya M, Matsuda S, Kittaka M, Shiba H, Kurihara H: Sequential process in brain-derived neurotrophic factor-induced functional periodontal tissue regeneration. Eur J Oral Sci, 124: 141, 2016. 8) Nakahashi T, Fujimura H, Altar CA, Li J, Kambayashi J, Tandon NN, Sun B: Vascular endothelial cells synthesize and secrete brain-derived neurotrophic factor. FEBS Lett, 470: 113, 2000. 12) Tapia-Arancibia L, Aliaga E, Silhol M, Arancibia S: New insights into brain BDNF function in normal aging and Alzheimer disease. Brain Res Rev, 59: 201, 2008. 18) Yamanaka M, Tsuchida A, Nakagawa T, Nonomura T, Ono-Kishino M, Sugaru E, Noguchi H, Taiji M: Brain-derived neurotrophic factor enhances glucose utilization in peripheral tissues of diabetic mice. Diabetes Obes Metab, 9: 59, 2007. 28) Takeda K, Sakai N, Shiba H, Nagahara T, Fujita T, Kajiya M, Iwata T, Matsuda S, Kawahara K, Kawaguchi H, Kurihara H: Characteristics of high-molecular-weight hyaluronic acid as a brain-derived neurotrophic factor scaffold in periodontal tissue regeneration. Tissue Eng Part A, 17: 955, 2011. 5) MacGrogan D, Saint-Andre JP, Dicou E: Expression of nerve growth factor and nerve growth factor receptor genes in human tissues and in prostatic adenocarcinoma cell lines. J Neurochem, 59: 1381, 1992. 9) Kerschensteiner M, Gallmeier E, Behrens L, Leal VV, Misgeld T, Klinkert WE, Kolbeck R, Hoppe E, Oropeza-Wekerle RL, Bartke I, Stadelmann C, Lassmann H, Wekerle H, Hohlfeld R: Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: a neuroprotective role of inflammation? J Exp Med, 189: 865, 1999. 15) Krishnan V, Nestler EJ: The molecular neurobiology of depression. Nature, 455: 894, 2008. 3) Furukawa Y, Furukawa S, Satoyoshi E, Hayashi K: Nerve growth factor secreted by mouse heart cells in culture. J Biol Chem, 259: 1259, 1984. 4) Otten U, Ehrhard P, Peck R: Nerve growth factor induces growth and differentiation of human B lymphocytes. Proc Natl Acad Sci U S A, 86: 10059, 1989. 25) Takeda K, Kermani P, Anastasia A, Obinata Y, Hempstead BL, Kurihara H: BDNF protects human vascular endothelial cells from TNFalpha-induced apoptosis. Biochem Cell Biol, 91: 341, 2013. 24) Matsuda S, Fujita T, Kajiya M, Kashiwai K, Takeda K, Shiba H, Kurihara H: Brain-derived neurotrophic factor prevents the endothelial barrier dysfunction induced by interleukin-1beta and tumor necrosis factor-alpha. J Periodontal Res, 50: 444, 2015. 17) Maekawa F, Fujiwara K, Toriya M, Maejima Y, Nishio T, Toyoda Y, Nohara K, Yashiro T, Yada T: Brain-derived neurotrophic factor in VMH as the causal factor for and therapeutic tool to treat visceral adiposity and hyperleptinemia in type 2 diabetic Goto-Kakizaki rats. Front Synaptic Neurosci, 5: 7, 2013. 21) Takeda K, Shiba H, Mizuno N, Hasegawa N, Mouri Y, Hirachi A, Yoshino H, Kawaguchi H, Kurihara H: Brain-derived neurotrophic factor enhances periodontal tissue regeneration. Tissue Eng, 11: 1618, 2005. 11) Nosrat CA, Fried K, Lindskog S, Olson L: Cellular expression of neurotrophin mRNAs during tooth development. Cell Tissue Res, 290: 569, 1997. 6) Yamashiro T, Fukunaga T, Yamashita K, Kobashi N, Takano-Yamamoto T: Gene and protein expression of brain-derived neurotrophic factor and TrkB in bone and cartilage. Bone, 28: 404, 2001. 16) Buchman AS, Yu L, Boyle PA, Schneider JA, De Jager PL, Bennett DA: Higher brain BDNF gene expression is associated with slower cognitive decline in older adults. Neurology, 86: 735, 2016. |
| References_xml | – reference: 3) Furukawa Y, Furukawa S, Satoyoshi E, Hayashi K: Nerve growth factor secreted by mouse heart cells in culture. J Biol Chem, 259: 1259, 1984. – reference: 4) Otten U, Ehrhard P, Peck R: Nerve growth factor induces growth and differentiation of human B lymphocytes. Proc Natl Acad Sci U S A, 86: 10059, 1989. – reference: 30) Jimbo R, Tovar N, Janal MN, Mousa R, Marin C, Yoo D, Teixeira HS, Anchieta RB, Bonfante EA, Konishi A, Takeda K, Kurihara H, Coelho PG: The effect of brain-derived neurotrophic factor on periodontal furcation defects. PLoS One, 9: e84845, 2014. – reference: 19) Nonomura T, Tsuchida A, Ono-Kishino M, Nakagawa T, Taiji M, Noguchi H: Brain-derived neurotrophic factor regulates energy expenditure through the central nervous system in obese diabetic mice. Int J Exp Diabetes Res, 2: 201, 2001. – reference: 7) Nakanishi T, Takahashi K, Aoki C, Nishikawa K, Hattori T, Taniguchi S: Expression of nerve growth factor family neurotrophins in a mouse osteoblastic cell line. Biochem Biophys Res Commun, 198: 891, 1994. – reference: 9) Kerschensteiner M, Gallmeier E, Behrens L, Leal VV, Misgeld T, Klinkert WE, Kolbeck R, Hoppe E, Oropeza-Wekerle RL, Bartke I, Stadelmann C, Lassmann H, Wekerle H, Hohlfeld R: Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: a neuroprotective role of inflammation? J Exp Med, 189: 865, 1999. – reference: 28) Takeda K, Sakai N, Shiba H, Nagahara T, Fujita T, Kajiya M, Iwata T, Matsuda S, Kawahara K, Kawaguchi H, Kurihara H: Characteristics of high-molecular-weight hyaluronic acid as a brain-derived neurotrophic factor scaffold in periodontal tissue regeneration. Tissue Eng Part A, 17: 955, 2011. – reference: 5) MacGrogan D, Saint-Andre JP, Dicou E: Expression of nerve growth factor and nerve growth factor receptor genes in human tissues and in prostatic adenocarcinoma cell lines. J Neurochem, 59: 1381, 1992. – reference: 13) Tanila H: The role of BDNF in Alzheimer's disease. Neurobiol Dis, 2016. – reference: 17) Maekawa F, Fujiwara K, Toriya M, Maejima Y, Nishio T, Toyoda Y, Nohara K, Yashiro T, Yada T: Brain-derived neurotrophic factor in VMH as the causal factor for and therapeutic tool to treat visceral adiposity and hyperleptinemia in type 2 diabetic Goto-Kakizaki rats. Front Synaptic Neurosci, 5: 7, 2013. – reference: 26) Takeda K, Obinata Y, Konishi A, Kajiya M, Matsuda S, Mizuno N, Sasaki S, Fujita T, Kurihara H: Brain-Derived Neurotrophic Factor Inhibits Intercellular Adhesion Molecule-1 Expression in Interleukin-1beta-Treated Endothelial Cells. Cell Biochem Biophys, 2016. – reference: 23) Matsuda S, Fujita T, Kajiya M, Takeda K, Shiba H, Kawaguchi H, Kurihara H: Brain-derived neurotrophic factor induces migration of endothelial cells through a TrkB-ERK-integrin alphaVbeta3-FAK cascade. J Cell Physiol, 227: 2123, 2012. – reference: 8) Nakahashi T, Fujimura H, Altar CA, Li J, Kambayashi J, Tandon NN, Sun B: Vascular endothelial cells synthesize and secrete brain-derived neurotrophic factor. FEBS Lett, 470: 113, 2000. – reference: 18) Yamanaka M, Tsuchida A, Nakagawa T, Nonomura T, Ono-Kishino M, Sugaru E, Noguchi H, Taiji M: Brain-derived neurotrophic factor enhances glucose utilization in peripheral tissues of diabetic mice. Diabetes Obes Metab, 9: 59, 2007. – reference: 24) Matsuda S, Fujita T, Kajiya M, Kashiwai K, Takeda K, Shiba H, Kurihara H: Brain-derived neurotrophic factor prevents the endothelial barrier dysfunction induced by interleukin-1beta and tumor necrosis factor-alpha. J Periodontal Res, 50: 444, 2015. – reference: 14) Erickson KI, Miller DL, Roecklein KA: The aging hippocampus: interactions between exercise, depression, and BDNF. Neuroscientist, 18: 82, 2012. – reference: 15) Krishnan V, Nestler EJ: The molecular neurobiology of depression. Nature, 455: 894, 2008. – reference: 16) Buchman AS, Yu L, Boyle PA, Schneider JA, De Jager PL, Bennett DA: Higher brain BDNF gene expression is associated with slower cognitive decline in older adults. Neurology, 86: 735, 2016. – reference: 20) Kurihara H, Shinohara H, Yoshino H, Takeda K, Shiba H: Neurotrophins in cultured cells from periodontal tissues. J Periodontol, 74: 76, 2003. – reference: 22) Kashiwai K, Kajiya M, Matsuda S, Ouhara K, Takeda K, Takata T, Kitagawa M, Fujita T, Shiba H, Kurihara H: Distinction Between Cell Proliferation and Apoptosis Signals Regulated by Brain-Derived Neurotrophic Factor in Human Periodontal Ligament Cells and Gingival Epithelial Cells. J Cell Biochem, 2015. – reference: 21) Takeda K, Shiba H, Mizuno N, Hasegawa N, Mouri Y, Hirachi A, Yoshino H, Kawaguchi H, Kurihara H: Brain-derived neurotrophic factor enhances periodontal tissue regeneration. Tissue Eng, 11: 1618, 2005. – reference: 12) Tapia-Arancibia L, Aliaga E, Silhol M, Arancibia S: New insights into brain BDNF function in normal aging and Alzheimer disease. Brain Res Rev, 59: 201, 2008. – reference: 27) Mitsui Y, Gotoh M, Nakama K, Yamada T, Higuchi F, Nagata K: Hyaluronic acid inhibits mRNA expression of proinflammatory cytokines and cyclooxygenase-2/prostaglandin E (2) production via CD44 in interleukin-1-stimulated subacromial synovial fibroblasts from patients with rotator cuff disease. J Orthop Res, 26: 1032, 2008. – reference: 11) Nosrat CA, Fried K, Lindskog S, Olson L: Cellular expression of neurotrophin mRNAs during tooth development. Cell Tissue Res, 290: 569, 1997. – reference: 29) Konishi A, Takeda K, Fujita T, Kajiya M, Matsuda S, Kittaka M, Shiba H, Kurihara H: Sequential process in brain-derived neurotrophic factor-induced functional periodontal tissue regeneration. Eur J Oral Sci, 124: 141, 2016. – reference: 6) Yamashiro T, Fukunaga T, Yamashita K, Kobashi N, Takano-Yamamoto T: Gene and protein expression of brain-derived neurotrophic factor and TrkB in bone and cartilage. Bone, 28: 404, 2001. – reference: 10) Asaumi K, Nakanishi T, Asahara H, Inoue H, Takigawa M: Expression of neurotrophins and their receptors (TRK) during fracture healing. Bone, 26: 625, 2000. – reference: 1) Barbacid M: The Trk family of neurotrophin receptors. J Neurobiol, 25: 1386, 1994. – reference: 25) Takeda K, Kermani P, Anastasia A, Obinata Y, Hempstead BL, Kurihara H: BDNF protects human vascular endothelial cells from TNFalpha-induced apoptosis. Biochem Cell Biol, 91: 341, 2013. – reference: 2) Barrett GL: The p75 neurotrophin receptor and neuronal apoptosis. Prog Neurobiol, 61: 205, 2000. |
| SSID | ssib000872039 ssib023160750 ssib002822002 ssib005901892 ssj0041828 ssib002484695 ssib005880044 ssib004298385 |
| Score | 2.0207257 |
| SourceID | jstage |
| SourceType | Publisher |
| StartPage | 91 |
| SubjectTerms | サイトカイン療法 歯周組織再生 脳由来神経栄養因子 |
| Title | 脳由来神経栄養因子（BDNF）を用いた新しい歯周炎治療の開発 |
| URI | https://www.jstage.jst.go.jp/article/perio/58/3/58_91/_article/-char/ja |
| Volume | 58 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| ispartofPNX | 日本歯周病学会会誌, 2016/09/30, Vol.58(3), pp.91-97 |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpR1NaxUxcCn1oBfxE7_pwZxk635lk1yE7Hu7FMWCUqG3ZXff9vAOrUh78fZKD34hKqVSRO3BQi_1Ey_af_PoW3vqX3Am2W1T6aG28FjmJZNJZia7mQmTiWVdpwXmQROuXXKntIPQC2xR0tzmnamOV-YizAvc77g7Ho49CG5P0smh4VtG1NLcbD5aPN73XMlhtAploFc8Jfsfmt0hCgUAg37hCRqG54F0TGJOeEAin8SMCABcEodEtImkWAJPESMQUcJbWCUdxI8FkWBCShIDQoSFAMg2EQAkJGoRzqP2eNL8EST2CfeI8OpuJFclrqKlAJGojkMSOU0JM3BCpC4T1Z-rmjMkyGOsijwSRYqywELdSsY4SiDIm6p6Q6HbcB5iF8gnAC0iW_v3Ajic1uzJkMQBciSkAXAiJUinmXiIC5JBmewMjaJgYSAwG9UfgT-kIMnuNocaSEJ4UtcIqvFhVNDY24PWJlHcqMzRaAy5EGrwQCLiJj7gREprnKHMarJKJqqziOj7aJrdG32sVL1pStJ6vBSFihwLHABODKo0Fqo-QQxC9RXULAO_QkkXZhcCNbs3jih5Y-HxOQZ01uHGpV4Y4TtvB466Bnpn5aTc-EL4xjKoL2CrDSodf_3vUg2WPGa6xXTeM6OUjzZN9uQ-r9-sVGGllKc-PoSbNhV4NDHtgn90zGPMxZDeO_dM9wKDDEzzH6xtM50fWMeOmf7OE9w3cjlRYNoxzF88p813oxDANQrR4m4svwB8dWX5NfLT54GR05sGn2DrdsHza6JGlSE7cco6WXugI1Lzdtoa6mZnrONtjBrEix_PWvf_LPyoFr8N3q9Wqx-qny8GKwtbn55tvlvZXH-1vfEEPw3bG0_782-qxbV-b6Hf-zhY-trvvQV4sP5l8_VaNf9y8P13tTzf733eWnpeLf86Z00k8URrzK6vXrG7LuOZzXy3ZK5XOCwXmfDLIivwyHoRdgLw8MQUfPp5IVgOuJ7PsiIrpygFa79wOyUm1DpvDU_PTJcXrBFWdpySZ9T1izBwOzwT4PLw3BFgF3sg8YsW09JIH-r0OulBlX7p0C0vWyfwXdQ7qVes4dlHc-VV8C1m82tqAv0F_Pnncw |
| linkProvider | Colorado Alliance of Research Libraries |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=%E8%84%B3%E7%94%B1%E6%9D%A5%E7%A5%9E%E7%B5%8C%E6%A0%84%E9%A4%8A%E5%9B%A0%E5%AD%90%EF%BC%88BDNF%EF%BC%89%E3%82%92%E7%94%A8%E3%81%84%E3%81%9F%E6%96%B0%E3%81%97%E3%81%84%E6%AD%AF%E5%91%A8%E7%82%8E%E6%B2%BB%E7%99%82%E3%81%AE%E9%96%8B%E7%99%BA&rft.jtitle=%E6%97%A5%E6%9C%AC%E6%AD%AF%E5%91%A8%E7%97%85%E5%AD%A6%E4%BC%9A%E4%BC%9A%E8%AA%8C&rft.au=%E5%8A%A0%E6%B2%BB%E5%B1%8B%2C+%E5%B9%B9%E4%BA%BA&rft.au=%E6%9F%8F%E4%BA%95%2C+%E6%A1%82&rft.au=%E6%9D%BE%E7%94%B0%2C+%E7%9C%9F%E5%8F%B8&rft.au=%E6%B0%B4%E9%87%8E%2C+%E6%99%BA%E4%BB%81&rft.date=2016&rft.pub=%E7%89%B9%E5%AE%9A%E9%9D%9E%E5%96%B6%E5%88%A9%E6%B4%BB%E5%8B%95%E6%B3%95%E4%BA%BA+%E6%97%A5%E6%9C%AC%E6%AD%AF%E5%91%A8%E7%97%85%E5%AD%A6%E4%BC%9A&rft.issn=0385-0110&rft.eissn=1880-408X&rft.volume=58&rft.issue=3&rft.spage=91&rft.epage=97&rft_id=info:doi/10.2329%2Fperio.58.91&rft.externalDocID=article_perio_58_3_58_91_article_char_ja |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0385-0110&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0385-0110&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0385-0110&client=summon |