Rapid bactericidal activity of sitafloxacin against Streptococcus pneumoniae

• Published in: Japanese journal of antibiotics Vol. 66; no. 1; p. 9
• Main Authors: Kanda, Hiroko, Inoue, Kazue, Okumura, Ryo, Hoshino, Kazuki
• Format: Journal Article
• Language: English
• Published: Japan 01.02.2013
• Subjects: Anti-Bacterial Agents - pharmacology; Fluoroquinolones - pharmacology; Humans; Microbial Sensitivity Tests; Streptococcus pneumoniae - drug effects

The initial bactericidal activity of quinolones against Streptococcus pneumoniae at the concentration equivalent to their respective peak serum concentration (C(max)) and free drug fraction of C(max) (fC(max)) were investigated. The bactericidal activity of sitafloxacin (STFX), levofloxacin (LVFX),...