Effect of Raspberry Ketone Bathing on the Skin Blood Flow and Endocrine System

To investigate the scientific grounds for the effect of raspberry ketone bathing that is claimed to increase energy consumption by stimulating metabolism, a bathing experiment was conducted in 10 normal healthy adults. As a result, no appreciable difference was detected among tap water, CO2-enriched...

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Published inThe Journal of The Japanese Society of Balneology, Climatology and Physical Medicine Vol. 67; no. 4; pp. 215 - 224
Main Authors SAITO, Masato, MAEDA, Masaharu, IKEMOTO, Takeshi
Format Journal Article
LanguageJapanese
Published The Japanese Society of Balneology, Climatology and Physical Medicine 01.08.2004
Subjects
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ISSN0029-0343
1884-3697
DOI10.11390/onki1962.67.215

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Abstract To investigate the scientific grounds for the effect of raspberry ketone bathing that is claimed to increase energy consumption by stimulating metabolism, a bathing experiment was conducted in 10 normal healthy adults. As a result, no appreciable difference was detected among tap water, CO2-enriched water and raspberry water in respect to blood pressure, pulse rate and depth thermometer readings, which suggested that bathing in warm raspberry water was safe, producing no marked load on the cardiovascular system. Changes in the skin surface temperature indicated slow elevation of body temperature, from which bathing in warm raspberry water was considered to produce no marked load on the body even if bathing lasted relatively long as compared with bathing in warm tap water or CO2-enriched warm water. From the skin tissue blood flow data, it seemed likely that the increase in blood flow caused by bathing in warm raspberry water was produced, not by vasodilatation as in CO2-enriched warm water bathing, but by such mechanisms as acceleration of metabolism. Data on insulin suggested that bathing in warm raspberry water affected the carbohydrate metabolism as compared with that in warm tap water or CO2-enriched warm water. Since there was no difference among warm water groups in changes in the adrenocortical hormone “cortisol”, raspberry ketone bathing was considered not to have specific activity. Data on NK cell activity showed that bathing in warm raspberry water produced no appreciable effect on the immune system. It was suggested that measurement of β-endorphin should be performed after adjustment of psychological environments. The results of expiration air analysis also indicated that, while bathing in CO2-enriched warm water was related to changes in the cardiovascular system, bathing in warm raspberry ketone water produced no appreciable load on the cardiovascular system but consumed energy through acceleration of metabolic activities.
AbstractList 「I INTRODUCTION」 Raspberry ketone used as a bath product is said to activate the metabolism of the body and increase energy consumption. However, there is only a limited literature on the scientific grounds for this claim. To prove the efficacy of raspberry ketone bathing salt scientifically, we attempted analysis of its effect on the metabolic activities of the body, using skin blood flow, body temperature and oxygen consumption as indicators. Its safety as a bathing in warm raspberry ketone water was also studied by evaluating its effects on the endocrine and immune systems. 「II SUBJECTS」 With 10 healthy college students (5 men, 5 women, age 20.5±1.4) without skin disease, endocrine/ metabolic disease or immune disorder as subjects, the experiment was conducted from 5 to 21 March 2003. (Table 1) 「III ABOUT RASPBERRY KETONE BATH SALT」 4-(4-Hydroxyphenyl)-2-butanone contained in raspberry fruits in the genus Rubus of the rose family that have a characteristic fragrance is called raspberry ketone.
To investigate the scientific grounds for the effect of raspberry ketone bathing that is claimed to increase energy consumption by stimulating metabolism, a bathing experiment was conducted in 10 normal healthy adults. As a result, no appreciable difference was detected among tap water, CO2-enriched water and raspberry water in respect to blood pressure, pulse rate and depth thermometer readings, which suggested that bathing in warm raspberry water was safe, producing no marked load on the cardiovascular system. Changes in the skin surface temperature indicated slow elevation of body temperature, from which bathing in warm raspberry water was considered to produce no marked load on the body even if bathing lasted relatively long as compared with bathing in warm tap water or CO2-enriched warm water. From the skin tissue blood flow data, it seemed likely that the increase in blood flow caused by bathing in warm raspberry water was produced, not by vasodilatation as in CO2-enriched warm water bathing, but by such mechanisms as acceleration of metabolism. Data on insulin suggested that bathing in warm raspberry water affected the carbohydrate metabolism as compared with that in warm tap water or CO2-enriched warm water. Since there was no difference among warm water groups in changes in the adrenocortical hormone “cortisol”, raspberry ketone bathing was considered not to have specific activity. Data on NK cell activity showed that bathing in warm raspberry water produced no appreciable effect on the immune system. It was suggested that measurement of β-endorphin should be performed after adjustment of psychological environments. The results of expiration air analysis also indicated that, while bathing in CO2-enriched warm water was related to changes in the cardiovascular system, bathing in warm raspberry ketone water produced no appreciable load on the cardiovascular system but consumed energy through acceleration of metabolic activities.
Author IKEMOTO, Takeshi
SAITO, Masato
MAEDA, Masaharu
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References 6) Masaharu Maeda, Urara Sasaki, Hiroshi Nagasawa., Shinobu Shimizu, Katsura Tanaka, Shuichi Obuchi, Yoshitaka Shiba, Sumio Hoka: Changes in the Current Perception Threshold (CPT) Due to Artificial High Concentration CO2 Water Warm Bathing. J Jpn Assoc Phys Med Balned Climatol. 2001; 64: 191-199.
1) Masaharu Maeda, Shuichi Obuchi, Yoshitaka Shiba, Urara Sasaki, Koji Yorizumi, Katsura Tanaka, Hiroshi Nagasawa: Effects of the High Concentration CO2 Bathing on the Body Temperature (1st Report)—Changes of the deep body thermometer and the surface skin temperature by artificial high concentration CO2 warm water bathing—. J Jpn Assoc Phys Med Balned Climatol. 2001; 64: 113-117.
3) Takeshi Ikemoto: The effects of Raspberry ketone, typical aroma chemical of delicious Red Raspberry, on obesity. The Koryo 2003; 217: 129-133.
4) Nobuhiro Tokutome: Lifestyles and Chronic Non-communicable Diseases. Lifestyles and Cancer Prevention. Physical activity and cancer prevention. Supp. Symposium of Japanese Medical Association 1998; 110: 59-63.
2) Masaharu Maeda, Takako Tsuji, Urara Sasaki, Koji Yorizumi, Shuichi Obuchi, Hiroshi Nagasawa, Yoshitaka Shiba, Sumio Hoka: Changes of Current Perception Threshold on Sensory Nerve Fiber in Thermotherapy. J Jpn Assoc Phys Med Balned Climatol. 2000; 63: 143-150.
5) Keiko Hoshi: Stress and Immune Cells. Clinical Aspects. Prog Med 2003; 23: 561-566.
References_xml – reference: 2) Masaharu Maeda, Takako Tsuji, Urara Sasaki, Koji Yorizumi, Shuichi Obuchi, Hiroshi Nagasawa, Yoshitaka Shiba, Sumio Hoka: Changes of Current Perception Threshold on Sensory Nerve Fiber in Thermotherapy. J Jpn Assoc Phys Med Balned Climatol. 2000; 63: 143-150.
– reference: 6) Masaharu Maeda, Urara Sasaki, Hiroshi Nagasawa., Shinobu Shimizu, Katsura Tanaka, Shuichi Obuchi, Yoshitaka Shiba, Sumio Hoka: Changes in the Current Perception Threshold (CPT) Due to Artificial High Concentration CO2 Water Warm Bathing. J Jpn Assoc Phys Med Balned Climatol. 2001; 64: 191-199.
– reference: 4) Nobuhiro Tokutome: Lifestyles and Chronic Non-communicable Diseases. Lifestyles and Cancer Prevention. Physical activity and cancer prevention. Supp. Symposium of Japanese Medical Association 1998; 110: 59-63.
– reference: 5) Keiko Hoshi: Stress and Immune Cells. Clinical Aspects. Prog Med 2003; 23: 561-566.
– reference: 1) Masaharu Maeda, Shuichi Obuchi, Yoshitaka Shiba, Urara Sasaki, Koji Yorizumi, Katsura Tanaka, Hiroshi Nagasawa: Effects of the High Concentration CO2 Bathing on the Body Temperature (1st Report)—Changes of the deep body thermometer and the surface skin temperature by artificial high concentration CO2 warm water bathing—. J Jpn Assoc Phys Med Balned Climatol. 2001; 64: 113-117.
– reference: 3) Takeshi Ikemoto: The effects of Raspberry ketone, typical aroma chemical of delicious Red Raspberry, on obesity. The Koryo 2003; 217: 129-133.
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Snippet To investigate the scientific grounds for the effect of raspberry ketone bathing that is claimed to increase energy consumption by stimulating metabolism, a...
「I INTRODUCTION」 Raspberry ketone used as a bath product is said to activate the metabolism of the body and increase energy consumption. However, there is only...
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SubjectTerms bath product
bathing
Raspberry ketone
Title Effect of Raspberry Ketone Bathing on the Skin Blood Flow and Endocrine System
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