CLINICAL STUDY OF IMIPENEM/CILASTATIN SODIUM PART II THE EFFECT OF IMIPENEM/CILASTATIN SODIUM ON PLATELET FUNCTION AND BLOOD COAGULATION

• Published in: CHEMOTHERAPY Vol. 37; no. 7; pp. 896 - 902
• Main Authors: AKIZAWA, TAKANORI, NAKAGAMI, KAZUKIYO, SUZUKI, HAJIME, NOGUCHI, EISEI, TERADA, HIDEO
• Format: Journal Article
• Language: English; Japanese
• Published: Japanese Society of Chemotherapy 1989

Recently, a tendency to bleed as a side effect of antibiotics has been given attention. We studied the effect of imipenem/cilastatin sodium (IPM/CS), a carbapenem antibiotic which belongs to a new class of beta-lactam agents, on platelet function and blood coagulation. The subjects were 11 patients...