HISTOPATHOLOGICAL STUDIES ON THE JEJUNAL WALL AND ITS REGIONAL MESENTERIC LYMPHNODES OF HOOK WORM INFESTATION

• Published in: Journal of The Showa Medical Association Vol. 20; no. 9; pp. 1214 - 1229
• Main Author: Sasaki, Shinji
• Format: Journal Article
• Language: English; Japanese
• Published: The Showa University Society 1960
• ISSN: 0037-4342; 2185-0976
• DOI: 10.14930/jsma1939.20.1214

Clinical and histopathological investigations ware made on the wall of the jejunum and related mesenteric lymph nodes of operation cases in whom the infestation of hook worms had been confirmed by the presence of eggs in their feces or by the detection of the hook worm on the intestinal wall. Stated in the following are the results obtained thereof: 1. Infestation of hook worms causes the development of subacute or chronic inflammatory changes on the upper jejunum. Histopathologically, those changes are characterized by the appearance of relatively marked infiltration of eosionophiles in each layer of the intestinal wall. 2. Following the changes produced on the intestinal wall, regional lymph nodes are found to be enlarged showing the state of sinus catarrh and chronic lymphadenitis histopathologically characterized by the marked infiltration of eosinophiles. 3. intensity of these changes appears in proportion to that of the infestation of the hook worms and they can be the cause for the development of various digestive symptoms such as epigastric pain, nausea, vomiting etc.