1）神経変性疾患のトランスレーショナルリサーチ
Saved in:
| Published in | 日本内科学会雑誌 Vol. 101; no. 9; pp. 2533 - 2538 |
|---|---|
| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
一般社団法人 日本内科学会
2012
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 0021-5384 1883-2083 |
| DOI | 10.2169/naika.101.2533 |
Cover
| Author | 田中, 章景 勝野, 雅央 橋詰, 淳 足立, 弘明 坂野, 晴彦 祖父江, 元 鈴木, 啓介 |
|---|---|
| Author_xml | – sequence: 1 fullname: 祖父江, 元 organization: 名古屋大学大学院医学系研究科神経内科 – sequence: 1 fullname: 田中, 章景 organization: 名古屋大学大学院医学系研究科神経内科 – sequence: 1 fullname: 坂野, 晴彦 organization: 名古屋大学高等研究院 – sequence: 1 fullname: 鈴木, 啓介 organization: 名古屋大学大学院医学系研究科神経内科 – sequence: 1 fullname: 勝野, 雅央 organization: 名古屋大学大学院医学系研究科神経内科 – sequence: 1 fullname: 足立, 弘明 organization: 名古屋大学大学院医学系研究科神経内科 – sequence: 1 fullname: 橋詰, 淳 organization: 名古屋大学大学院医学系研究科神経内科 |
| BookMark | eNo9kDtLA0EUhQeJYIxp_Rcb587sTHZKDb4gYKP1cvelG2OU3TR2ZqcxwdrSRiX4wEaCCME_czEp_QuaKDbnwPngFN8yK3VOOzFjq8BrArRZ62B6jDXgUBNKygVWBs-TjuCeLLEy5wIcJT13iVXzPA24K7XyQLpl1oCvcX96fzMdXX3e9ScXw-n1x6S4pd4L2UuyD2RfqXgn-0x2TMUb2SHZAdknso9UjGaj7a2wxQTbeVz96wo72Nrcb-w4zb3t3cZ602mB5tzRYFQShgmoABFFXSfGKEQvAEwkxFEAoDggD8MgCcDVQrlaRUaDkGjqJpIVtvH728q7eBj7Z1l6gtm5j1k3DduxP3fg_zjwzTxnJv5heISZ30L5DXQ1cA4 |
| ContentType | Journal Article |
| Copyright | 2012 一般社団法人 日本内科学会 |
| Copyright_xml | – notice: 2012 一般社団法人 日本内科学会 |
| DOI | 10.2169/naika.101.2533 |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1883-2083 |
| EndPage | 2538 |
| ExternalDocumentID | article_naika_101_9_101_2533_article_char_ja |
| GroupedDBID | 2WC ALMA_UNASSIGNED_HOLDINGS DIK F5P JSF OK1 RJT ZXP |
| ID | FETCH-LOGICAL-j1600-6195fccf15baaa276f995aa8b1af31edb11501a0ccbfb14625465d96123a979d3 |
| ISSN | 0021-5384 |
| IngestDate | Wed Sep 03 06:30:35 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | false |
| IsScholarly | true |
| Issue | 9 |
| Language | Japanese |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-j1600-6195fccf15baaa276f995aa8b1af31edb11501a0ccbfb14625465d96123a979d3 |
| OpenAccessLink | https://www.jstage.jst.go.jp/article/naika/101/9/101_2533/_article/-char/ja |
| PageCount | 6 |
| ParticipantIDs | jstage_primary_article_naika_101_9_101_2533_article_char_ja |
| PublicationCentury | 2000 |
| PublicationDate | 2012 |
| PublicationDateYYYYMMDD | 2012-01-01 |
| PublicationDate_xml | – year: 2012 text: 2012 |
| PublicationDecade | 2010 |
| PublicationTitle | 日本内科学会雑誌 |
| PublicationTitleAlternate | 日内会誌 |
| PublicationYear | 2012 |
| Publisher | 一般社団法人 日本内科学会 |
| Publisher_xml | – name: 一般社団法人 日本内科学会 |
| References | 2) Rosen DR, et al: Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362: 59-62, 1993. 12) Cudkowicz ME, et al: Toward more efficient clinical trials for amyotrophic lateral sclerosis. Amyotroph Lateral Scler 11: 259-265, 2010. 11) Goedert M, et al: The propagation of prion-like protein inclusions in neurodegenerative diseases. Trends Neurosci 33: 317-325, 2010. 1) Goate A, et al: Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 349: 704-706, 1991. 6) Shulman JM, et al: Pakinson's disease: genetics and pathogenesis. Annu Rev Pathol 6: 193-222, 2011. 9) Cohen TJ, et al: TDP-43 functions and pathogenic mechanisms implicated in TDP-43 proteinopathies. Trends Mol Med 17: 659-667, 2011. 7) Katsuno M, et al; Japan SBMA Interventional Trial for TAP-144-SR (JASMITT) study group: Efficacy and safety of leuprorelin in patients with spinal and bulbar muscular atrophy (JASMITT study): a multicentre, randomised, double-blind, placebo-controlled trial. Lancet Neurol 9: 875-884, 2010. 4) Zinman L, Cudkowicz M: Emerging targets and treatments in amyotrophic lateral sclerosis. Lancet Neurol 10: 481-490, 2011. 3) Holmes C, et al: Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial. Lancet 372: 216-223, 2008. 8) Hashizume A, et al: Difference in chronological changes of outcome measures between untreated and placebo-treated patients of spinal and bulbar muscular atrophy. J Neurol 259: 712-719, 2011. 10) Boillée S, et al: Onset and progression in inherited ALS determined by motor neurons and microglia. Science 312: 1389-1392, 2006. 5) Katsuno M, et al: Perspectives on molecular targeted therapies and clinical trials for neurodegenerative diseases. J Neurol Neurosurg Psychiatry 83: 329-335, 2012. |
| References_xml | – reference: 2) Rosen DR, et al: Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362: 59-62, 1993. – reference: 7) Katsuno M, et al; Japan SBMA Interventional Trial for TAP-144-SR (JASMITT) study group: Efficacy and safety of leuprorelin in patients with spinal and bulbar muscular atrophy (JASMITT study): a multicentre, randomised, double-blind, placebo-controlled trial. Lancet Neurol 9: 875-884, 2010. – reference: 1) Goate A, et al: Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 349: 704-706, 1991. – reference: 10) Boillée S, et al: Onset and progression in inherited ALS determined by motor neurons and microglia. Science 312: 1389-1392, 2006. – reference: 9) Cohen TJ, et al: TDP-43 functions and pathogenic mechanisms implicated in TDP-43 proteinopathies. Trends Mol Med 17: 659-667, 2011. – reference: 4) Zinman L, Cudkowicz M: Emerging targets and treatments in amyotrophic lateral sclerosis. Lancet Neurol 10: 481-490, 2011. – reference: 5) Katsuno M, et al: Perspectives on molecular targeted therapies and clinical trials for neurodegenerative diseases. J Neurol Neurosurg Psychiatry 83: 329-335, 2012. – reference: 3) Holmes C, et al: Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial. Lancet 372: 216-223, 2008. – reference: 11) Goedert M, et al: The propagation of prion-like protein inclusions in neurodegenerative diseases. Trends Neurosci 33: 317-325, 2010. – reference: 6) Shulman JM, et al: Pakinson's disease: genetics and pathogenesis. Annu Rev Pathol 6: 193-222, 2011. – reference: 12) Cudkowicz ME, et al: Toward more efficient clinical trials for amyotrophic lateral sclerosis. Amyotroph Lateral Scler 11: 259-265, 2010. – reference: 8) Hashizume A, et al: Difference in chronological changes of outcome measures between untreated and placebo-treated patients of spinal and bulbar muscular atrophy. J Neurol 259: 712-719, 2011. |
| SSID | ssib043658134 ssj0066765 ssib002821954 ssib005879745 ssib007485360 ssib058493862 ssib000940260 ssib002484664 |
| Score | 1.8811975 |
| SourceID | jstage |
| SourceType | Publisher |
| StartPage | 2533 |
| SubjectTerms | エンドポイント トランスレーショナルリサーチ バイオマーカー 神経変性疾患 臨床試験 |
| Title | 1）神経変性疾患のトランスレーショナルリサーチ |
| URI | https://www.jstage.jst.go.jp/article/naika/101/9/101_2533/_article/-char/ja |
| Volume | 101 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| ispartofPNX | 日本内科学会雑誌, 2012, Vol.101(9), pp.2533-2538 |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpR1NaxQxdKgVxIv4id_0YE4ydZOZTBI8ZaazFKWC0EJvy3we9lBFthdPdudixbNHLyrFD7xIEaH4Zwa7R2-efS8z2Z2FHmyFYXibvLy8j83mvWzy4jh30pLlLClKF7w33_VZKl1ZwHBXXLKUwa-yZ_4uWHsUrG74Dzb55sKpP51dS9ujdDl7fuS5kpNYFcrArnhK9hiWnRKFAoDBvvAGC8P7n2xMSdwnYUSkIrEgmhMVIxByIiMSc6J9UxXgdgYtsEoFJIxNCSPaI7EHniTRsQHgkS2gVQuEDQ4joS3Rka2KbJWwVRaQ2paEFtAWmc83Rwa6DjLypowsCESmOxAHGOZGRhCBGtFWiA5I7CMdBcQVUaGpktiXnK79WsUECIB8YYCEQ0pUH79dhjg8XhdfAdWeoS2xH4MmUBbdM1wpovszfCC-gpIBCxK6iBt8gxb6WB0iqzN8ZdjwrXzSsqHg8UyvIZFhdzWGzqL2liuwJwgKdFA9Au2MVuWoA7RqgHYDeois4bl7Mq12ZzRGXZi0mkWZopnEpPRgnLSqs7Ncu2bUDGfVnbN4k4qk9X_gozxqbmU0wNS0W3iyDdd8lmft5vKVt6NhYBBxB-FAmTeiD2wlHikcDCGuOc2EoLgV9-HjTligfEx113Ej5dwtCEwy2k1jyKVQ3VsbhA9O6Ky974GbTWdpEMHnVp4MpmnmcJt3c9NJq8smuSsKfG9eXHBThxC02Q2fxgddP--ca4PHJd2Id8FZGCYXnTNr7faYS05Efx_sTj68ney__vV-9_DF3uTNz8Pxu3rna129rKuPdfWtHv-oqy91dVCPv9fVXl29qqvPdfWpHu9jYbVz2dnox-vRqtvekuIOKUQrbgCqKLOspDxNkoSJoFSKJ4lMaVJ6tMhTjPlo0suytEzBL8ILMHiuMO1SooTKvSvO4taTreKqs1SWKs9EwQsvE36RpIrnrIdH1XPQrs-Ka879RvzB0yYVzuA4xr7-X61vOGdxvDWrnzedxdGz7eIWxAOj9Lb58vwFZzLP8w |
| linkProvider | Colorado Alliance of Research Libraries |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=1%EF%BC%89%E7%A5%9E%E7%B5%8C%E5%A4%89%E6%80%A7%E7%96%BE%E6%82%A3%E3%81%AE%E3%83%88%E3%83%A9%E3%83%B3%E3%82%B9%E3%83%AC%E3%83%BC%E3%82%B7%E3%83%A7%E3%83%8A%E3%83%AB%E3%83%AA%E3%82%B5%E3%83%BC%E3%83%81&rft.jtitle=%E6%97%A5%E6%9C%AC%E5%86%85%E7%A7%91%E5%AD%A6%E4%BC%9A%E9%9B%91%E8%AA%8C&rft.au=%E7%A5%96%E7%88%B6%E6%B1%9F%2C+%E5%85%83&rft.au=%E7%94%B0%E4%B8%AD%2C+%E7%AB%A0%E6%99%AF&rft.au=%E5%9D%82%E9%87%8E%2C+%E6%99%B4%E5%BD%A6&rft.au=%E9%88%B4%E6%9C%A8%2C+%E5%95%93%E4%BB%8B&rft.date=2012&rft.pub=%E4%B8%80%E8%88%AC%E7%A4%BE%E5%9B%A3%E6%B3%95%E4%BA%BA+%E6%97%A5%E6%9C%AC%E5%86%85%E7%A7%91%E5%AD%A6%E4%BC%9A&rft.issn=0021-5384&rft.eissn=1883-2083&rft.volume=101&rft.issue=9&rft.spage=2533&rft.epage=2538&rft_id=info:doi/10.2169%2Fnaika.101.2533&rft.externalDocID=article_naika_101_9_101_2533_article_char_ja |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0021-5384&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0021-5384&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0021-5384&client=summon |