胆汁酸と抱合

Saved in:
Bibliographic Details
Published in臨床化学 Vol. 36; no. 3; pp. 173 - 180
Main Authors 後藤, 貴章, 眞野, 成康
Format Journal Article
LanguageJapanese
Published 一般社団法人 日本臨床化学会 31.07.2007
Online AccessGet full text
ISSN0370-5633
2187-4077
DOI10.14921/jscc1971b.36.3_173

Cover

Author 眞野, 成康
後藤, 貴章
Author_xml – sequence: 1
  fullname: 後藤, 貴章
  organization: 東北大学大学院薬学研究科
– sequence: 1
  fullname: 眞野, 成康
  organization: 東北大学病院薬剤部
BookMark eNo9j71KA0EUhQeJ4BrT2PoMu967d35LWfwJBGy0HmYnM7pLjLKTxjKIIlY-hm0630cM-hauKOHAOcWBw_l22WB-Ow-MHSAUyE2Jh23yHo3CuiBZkEVFWywrUaucg1IDlgEpyIUk2mGjlJoagAOgkTpj-18PT-vV8vvx_WP5tn5Zfb4-77Ht6GYpjP5zyC5Pji-qs3xyfjqujiZ5iwJc7qPUhoPTEUuDtZuij1oKaWLgJpBAQQSlcEYpPwWOJmjeC6Uu0VN_Zsiqv902LdxVsHddc-O6e-u6ReNnwW6wLElLv9aTbVp_7TrbOvoBOv9OeA
ContentType Journal Article
Copyright 日本臨床化学会
Copyright_xml – notice: 日本臨床化学会
DOI 10.14921/jscc1971b.36.3_173
DeliveryMethod fulltext_linktorsrc
EISSN 2187-4077
EndPage 180
ExternalDocumentID article_jscc1971b_36_3_36_173_article_char_ja
GroupedDBID ---
ALMA_UNASSIGNED_HOLDINGS
JSF
KQ8
OK1
RJT
ID FETCH-LOGICAL-j150a-cf68940a8f1291bad1cf86569fe49e351533025a977cd0419e8484816821c3633
ISSN 0370-5633
IngestDate Wed Sep 03 06:29:46 EDT 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed false
IsScholarly true
Issue 3
Language Japanese
LinkModel OpenURL
MergedId FETCHMERGED-LOGICAL-j150a-cf68940a8f1291bad1cf86569fe49e351533025a977cd0419e8484816821c3633
OpenAccessLink https://www.jstage.jst.go.jp/article/jscc1971b/36/3/36_173/_article/-char/ja
PageCount 8
ParticipantIDs jstage_primary_article_jscc1971b_36_3_36_173_article_char_ja
PublicationCentury 2000
PublicationDate 2007/07/31
PublicationDateYYYYMMDD 2007-07-31
PublicationDate_xml – month: 07
  year: 2007
  text: 2007/07/31
  day: 31
PublicationDecade 2000
PublicationTitle 臨床化学
PublicationTitleAlternate 臨床化学
PublicationYear 2007
Publisher 一般社団法人 日本臨床化学会
Publisher_xml – name: 一般社団法人 日本臨床化学会
References 11) Trottier J, Verreault M, Grepper S, Monte D, Belanger J, Kaeding J, Caron P, Inaba TT, Barbier 0: Human UDP-glucuronosyltransferase (UGT) 1A3 enzyme conjugates chenodeoxycholic ac id in the liver, Hepatology, 44: 1158-1170, 2006.
17) Marschall HU, Egestad B, Matern H, Matern S, Sjovall J: N-acetylglucosaminides. A new type of bile acid conjugate in man, J Biol Chem, 264: 12989-12993, 1989.
14) Mano N, Nishimura K, Narui T, Ikegawa S, Goto J: Characterization of rat liver bile acid acyl glucuronosyltransferase, Steroids, 67: 257-2 62, 2002.
16) Marschall HU, Green G, Egestad B, SjOvall j: Isolation of bile acid glucosides and N-acetylglucosaminides from human urine by io nexchange chromatography and reversed-phase high-performance liquid chrom atography, J Chromatogr, 452: 459-4681988.
5) Alm6 B, SjOvall J: Bile acid profiles in urine of patients with liver diseases, Eur J Clin Invest, 9: 341-348, 1979.
24) Goto T, Shibata A, Sasaki D, Suzuki N, Hishinuma T, Kakivama G, Iida T, Mano N, Goto J: Identification of a novel conjugate in human urine: Bile acid acyl galactosides, Steroids, 70: 18 5-192, 2005.
25) Mallonee DH, Adams JL, Hylemon PB: he bile acidinducible baiB gene from Eubacterium sp. strain VPI 12708e ncodes a bile acid-coenzyme A lig ase, J Bacteriol, 174: 2065-2071, 1 992.
26) Kelley M, Vessey DA; Determination of the mechanism of reaction for bile acid: Co Aligase, BiochemJ, 304: 945-949, 1 994.
20) Matern H, Matern S, Gerok W: Formation of bile acid glucosides by a sugar nucleotide-independent glucosyltransferase isolate d from human liver microsomes, Proc Natl Acad Sci USA, 81: 7036-7040, 1984.
9) Goto J, Murao N, Nakada C, Motoyama T, Oohashi J, Yanagihara T, Niwa T, Ikegawa S: Sep aration and characterization of carboxy l-linked glucuronides of bile acids in incub ation mixture of rat liver microsomes, Steroids, 63: 186-192, 1998.
7) Goto T, Khin Than Myint, Sato K, Wada 0, Kakiyama G, Iida T, Hishinuma T, Mano N, Goto J: LC/ESI-Tandem mass spectrometric determination of bile acid 3-sulf ates in human urine. 3 /3- Sulfooxy-12 a -hydroxy-5 j3 - cho lanoic acid is an abundant nonamidated s ulfate, J Chromatogr B, 846: 69-77, 2007.
8) Back P, Spaczynski K, Gerok W: Bile-salt glucuronides in urine, Hoppe-Seyler's Z. Physiol Chem, 355: 749-752, 1974.
12) Ikegawa S, Murao N, Motoyama T, Yanagihara T, Niwa T, Goto J: Separation and detection of bile acid 3-glucuronides in human urine by liquid chromatography/electrospray ionization-m ass spectrometry, Biomed Chromatog r, 10: 313-317, 1996.
18) Niwa T, Fujita K, Goto J, Nambara T: Separation and characterization of urs deoxycholate 7-Nacetylglucosaminaides in human urine by h ighperformance liquid chromatography with fluorescence ditection, J Liquid Chromatogr, 16: 2531-2544, 1993.
28) Mitamura K, Sogabe M, Sakanashi H, Watanabe S, Sakai T, Yamaguchi Y, Wakamiya T, Ikegawa S: Analysis of bile acid glutathione thioesters by liquid chromatography/electrospray ionizatio ntandem mass spectrometry, J Chromatogr B, 2007, doi: 10.1016/j.jchromb.2007.02.010
6) Ikegawa S, Yanagihara T, Murao N, Watanabe H, Goto J, Niwa T: Separatory determination of bile acid 3-sulfates by liquid chromatography/electrospray ionization mass spectrometry, J Mass Spectrom, 32: 401-407, 1997.
23) Goto T, Shibata A, Iida T, Mano N, Goto J: Sensitive mass spectrometric detection of neutral bile acid metabolites. Formation of adductions with an organic anion in atmospheric pressure chemical ionization, Rapid Commun Mass Spectrom, 18: 2360-2364, 2004.
27) Ikegawa S, Ishikawa H, Oiwa H, Nagata M, Goto J, Kozaki T, Gotowda M, Asakawa N: Characterization of cholyl-adenylate in rat liver microsomes by liquid chromatography/electrospray ionization-mass spectrometry, Anal Biochem, 266: 125-132, 1 999.
2) LOOf L, Wengle B: Enzymatic sulphation of bile salts in man, Scand J Gastroenterol, 14: 513-519, 1979.
19) Matern H, Bolz R, Marschall HU, SjOvall J, Matern S: Bile acid N-acetylglucosaminides. Format ion by microsomal N-acetylglucosaminyltransferases in human liver and kidney, FEBS Lett, 270: 11-14, 1990.
22) Wietholtz H, Marschall HU, Reuschenbach R, Matern H, Matern S: Urinary excretion of bile acid glucosides and glucuronides in extrahepatic cholestasis, Hepatology, 13: 656-662, 1991.
3) Dew MJ, Hawker PC, Nutter S, Allan RN: Human intestinal sulphation of lithocholate: a new site for bile acid metabolism, Life Sci, 27: 317-323, 1980.
21) Marschall HU, Egestad B, Matern H, Matern S, SjOvall.1: Evidence for bile acid glucosides as normal constituents in human urine, FEBS Let t, 213: 411-414, 1987.
1) LOOf L, Wengle B: Enzymatic sulphation of bile salts in human liver, Biochim Biophys Acta, 530: 451-460, 1978.
13) Ikegawa S, Okuyama H, Oohashi J, Murao N, Goto J: Separation and detection of bile acid 24-glucuronides in human urine by liquid chromatography combined with electrosp ray ionization mass spectrometry, Anal Sci, 15: 625-631, 1999.
4) Ltiiif L: Enzymatic sulphation of bile salts in man. Bile salt sulphotransferase activity in hu man adrenal, Digestion, 21: 279-303, 1981.
15) Mano N, Goto T, Nikaido A, Narui T, Goto J: Inhibition of the rat hepatic microsomal flurbiprofen acyl glucuronidation by bile acids, J Pharm Sci, 92: 2098-2108, 2003.
10) Gall WE, Zawada G, Mojarrabi B, Tephly TR, Green MD, Coffman BL, Mackenzie PI, Radomin ska-Pandya A; Differential glucuronida tion of bile acids, androgens and estrogens by human UGT1A3 and 2B7, J Steroid Biochem Mol B iol, 70: 101-108, 1999.
References_xml – reference: 11) Trottier J, Verreault M, Grepper S, Monte D, Belanger J, Kaeding J, Caron P, Inaba TT, Barbier 0: Human UDP-glucuronosyltransferase (UGT) 1A3 enzyme conjugates chenodeoxycholic ac id in the liver, Hepatology, 44: 1158-1170, 2006.
– reference: 27) Ikegawa S, Ishikawa H, Oiwa H, Nagata M, Goto J, Kozaki T, Gotowda M, Asakawa N: Characterization of cholyl-adenylate in rat liver microsomes by liquid chromatography/electrospray ionization-mass spectrometry, Anal Biochem, 266: 125-132, 1 999.
– reference: 24) Goto T, Shibata A, Sasaki D, Suzuki N, Hishinuma T, Kakivama G, Iida T, Mano N, Goto J: Identification of a novel conjugate in human urine: Bile acid acyl galactosides, Steroids, 70: 18 5-192, 2005.
– reference: 12) Ikegawa S, Murao N, Motoyama T, Yanagihara T, Niwa T, Goto J: Separation and detection of bile acid 3-glucuronides in human urine by liquid chromatography/electrospray ionization-m ass spectrometry, Biomed Chromatog r, 10: 313-317, 1996.
– reference: 5) Alm6 B, SjOvall J: Bile acid profiles in urine of patients with liver diseases, Eur J Clin Invest, 9: 341-348, 1979.
– reference: 23) Goto T, Shibata A, Iida T, Mano N, Goto J: Sensitive mass spectrometric detection of neutral bile acid metabolites. Formation of adductions with an organic anion in atmospheric pressure chemical ionization, Rapid Commun Mass Spectrom, 18: 2360-2364, 2004.
– reference: 26) Kelley M, Vessey DA; Determination of the mechanism of reaction for bile acid: Co Aligase, BiochemJ, 304: 945-949, 1 994.
– reference: 9) Goto J, Murao N, Nakada C, Motoyama T, Oohashi J, Yanagihara T, Niwa T, Ikegawa S: Sep aration and characterization of carboxy l-linked glucuronides of bile acids in incub ation mixture of rat liver microsomes, Steroids, 63: 186-192, 1998.
– reference: 28) Mitamura K, Sogabe M, Sakanashi H, Watanabe S, Sakai T, Yamaguchi Y, Wakamiya T, Ikegawa S: Analysis of bile acid glutathione thioesters by liquid chromatography/electrospray ionizatio ntandem mass spectrometry, J Chromatogr B, 2007, doi: 10.1016/j.jchromb.2007.02.010
– reference: 14) Mano N, Nishimura K, Narui T, Ikegawa S, Goto J: Characterization of rat liver bile acid acyl glucuronosyltransferase, Steroids, 67: 257-2 62, 2002.
– reference: 19) Matern H, Bolz R, Marschall HU, SjOvall J, Matern S: Bile acid N-acetylglucosaminides. Format ion by microsomal N-acetylglucosaminyltransferases in human liver and kidney, FEBS Lett, 270: 11-14, 1990.
– reference: 8) Back P, Spaczynski K, Gerok W: Bile-salt glucuronides in urine, Hoppe-Seyler's Z. Physiol Chem, 355: 749-752, 1974.
– reference: 18) Niwa T, Fujita K, Goto J, Nambara T: Separation and characterization of urs deoxycholate 7-Nacetylglucosaminaides in human urine by h ighperformance liquid chromatography with fluorescence ditection, J Liquid Chromatogr, 16: 2531-2544, 1993.
– reference: 4) Ltiiif L: Enzymatic sulphation of bile salts in man. Bile salt sulphotransferase activity in hu man adrenal, Digestion, 21: 279-303, 1981.
– reference: 10) Gall WE, Zawada G, Mojarrabi B, Tephly TR, Green MD, Coffman BL, Mackenzie PI, Radomin ska-Pandya A; Differential glucuronida tion of bile acids, androgens and estrogens by human UGT1A3 and 2B7, J Steroid Biochem Mol B iol, 70: 101-108, 1999.
– reference: 25) Mallonee DH, Adams JL, Hylemon PB: he bile acidinducible baiB gene from Eubacterium sp. strain VPI 12708e ncodes a bile acid-coenzyme A lig ase, J Bacteriol, 174: 2065-2071, 1 992.
– reference: 6) Ikegawa S, Yanagihara T, Murao N, Watanabe H, Goto J, Niwa T: Separatory determination of bile acid 3-sulfates by liquid chromatography/electrospray ionization mass spectrometry, J Mass Spectrom, 32: 401-407, 1997.
– reference: 17) Marschall HU, Egestad B, Matern H, Matern S, Sjovall J: N-acetylglucosaminides. A new type of bile acid conjugate in man, J Biol Chem, 264: 12989-12993, 1989.
– reference: 22) Wietholtz H, Marschall HU, Reuschenbach R, Matern H, Matern S: Urinary excretion of bile acid glucosides and glucuronides in extrahepatic cholestasis, Hepatology, 13: 656-662, 1991.
– reference: 16) Marschall HU, Green G, Egestad B, SjOvall j: Isolation of bile acid glucosides and N-acetylglucosaminides from human urine by io nexchange chromatography and reversed-phase high-performance liquid chrom atography, J Chromatogr, 452: 459-4681988.
– reference: 13) Ikegawa S, Okuyama H, Oohashi J, Murao N, Goto J: Separation and detection of bile acid 24-glucuronides in human urine by liquid chromatography combined with electrosp ray ionization mass spectrometry, Anal Sci, 15: 625-631, 1999.
– reference: 21) Marschall HU, Egestad B, Matern H, Matern S, SjOvall.1: Evidence for bile acid glucosides as normal constituents in human urine, FEBS Let t, 213: 411-414, 1987.
– reference: 2) LOOf L, Wengle B: Enzymatic sulphation of bile salts in man, Scand J Gastroenterol, 14: 513-519, 1979.
– reference: 7) Goto T, Khin Than Myint, Sato K, Wada 0, Kakiyama G, Iida T, Hishinuma T, Mano N, Goto J: LC/ESI-Tandem mass spectrometric determination of bile acid 3-sulf ates in human urine. 3 /3- Sulfooxy-12 a -hydroxy-5 j3 - cho lanoic acid is an abundant nonamidated s ulfate, J Chromatogr B, 846: 69-77, 2007.
– reference: 1) LOOf L, Wengle B: Enzymatic sulphation of bile salts in human liver, Biochim Biophys Acta, 530: 451-460, 1978.
– reference: 3) Dew MJ, Hawker PC, Nutter S, Allan RN: Human intestinal sulphation of lithocholate: a new site for bile acid metabolism, Life Sci, 27: 317-323, 1980.
– reference: 20) Matern H, Matern S, Gerok W: Formation of bile acid glucosides by a sugar nucleotide-independent glucosyltransferase isolate d from human liver microsomes, Proc Natl Acad Sci USA, 81: 7036-7040, 1984.
– reference: 15) Mano N, Goto T, Nikaido A, Narui T, Goto J: Inhibition of the rat hepatic microsomal flurbiprofen acyl glucuronidation by bile acids, J Pharm Sci, 92: 2098-2108, 2003.
SSID ssib004001968
ssib058494216
ssj0003236072
Score 1.7161134
SourceID jstage
SourceType Publisher
StartPage 173
Title 胆汁酸と抱合
URI https://www.jstage.jst.go.jp/article/jscc1971b/36/3/36_173/_article/-char/ja
Volume 36
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
ispartofPNX 臨床化学, 2007/07/31, Vol.36(3), pp.173-180
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV0_b9UwELeeysKCqADxXx24MY84_neWWJKHUQUCCamVukWJkwxvKAheF7YKgRATH4O1G98HUcHMF-Ds5KWpigSFJXLsO_ucs86_c-wzY_c6KbSgmShpGysT2aksqdGLRKWVxU41lY6_C54-09u78vGe2pvNfk52LR2s6rl_89tzJf-iVcojvYZTsufQ7FgpZVCa9EtP0jA9_0rH4BBQAGpwGgpOqBCcBVRQIDgRXnMMRZiHUqfAptBfb7fGo7EGE8mIKw-UlMAFWB0S-UPIx6W7SOJCITFZYpJBP-GlyKCQ4CirgDw9oTdgqSYXhTKArqcneTBI0rdYmFMLD-OK5jBUwMnQG0yjpAj5IrYjgyShQ9SgiL0XYFUkpirz2EoQUcXEIrL9uaeRn3LyiXkUJk2U7sNozNuYR3jFkEc8XAwz2Pc-wMowjsXEWHMjJvM-72-UOjOlSJvFOeW199waXs-Fnoty5D0Vq3sYCeVIXApdivAg-nJdGs7TlUsC9RcyY-LegifPcWpU-SRgEQFEK9cBlgK8EJnQqen_jg1fYIimFSS9f1ZOwlZL8jTWuxQjcNq5zC4NHs9W3ou1yWbL6grb_P72_fHR4Y93X74efj7-ePTt04erbPeR21lsJ8P1HMmSvIgq8Z1GK9MKO8KMvK4a7jsk98B2rbStUMGTIERdkYfhm1Ry26IMlzdozLgnCyGusY39F_vtdbalVNNldc09-XpS2woN2YjKcNP4TsjM32AP-i6UL_sYLOW5vvTN_2O_xS6ejP_bbGP16qC9Q1B0Vd-NqvsF0JBjSQ
linkProvider Colorado Alliance of Research Libraries
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=%E8%83%86%E6%B1%81%E9%85%B8%E3%81%A8%E6%8A%B1%E5%90%88&rft.jtitle=%E8%87%A8%E5%BA%8A%E5%8C%96%E5%AD%A6&rft.au=%E5%BE%8C%E8%97%A4%2C+%E8%B2%B4%E7%AB%A0&rft.au=%E7%9C%9E%E9%87%8E%2C+%E6%88%90%E5%BA%B7&rft.date=2007-07-31&rft.pub=%E4%B8%80%E8%88%AC%E7%A4%BE%E5%9B%A3%E6%B3%95%E4%BA%BA+%E6%97%A5%E6%9C%AC%E8%87%A8%E5%BA%8A%E5%8C%96%E5%AD%A6%E4%BC%9A&rft.issn=0370-5633&rft.eissn=2187-4077&rft.volume=36&rft.issue=3&rft.spage=173&rft.epage=180&rft_id=info:doi/10.14921%2Fjscc1971b.36.3_173&rft.externalDocID=article_jscc1971b_36_3_36_173_article_char_ja
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0370-5633&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0370-5633&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0370-5633&client=summon