マクロファージ・リンパ球と動脈硬化の進展 特に接着蛋白ICAM-1/LFA-1とMMP-12の関わり

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Published in動脈硬化 Vol. 26; no. 4-5; pp. 173 - 177
Main Authors 渡辺, 照男, 松本, 俊一郎, 范, 江霖, 小林, 達伺
Format Journal Article
LanguageJapanese
Published 一般社団法人 日本動脈硬化学会 30.12.1998
Japan Atherosclerosis Society
Subjects
Online AccessGet full text
ISSN0386-2682
2185-8284
DOI10.5551/jat1973.26.4-5_173

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Author 渡辺, 照男
松本, 俊一郎
范, 江霖
小林, 達伺
Author_FL KOBAYASHI Tatsushi
FAN Janglin
MATSU-MOTO Shunichiro
WATANABE Teruo
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  fullname: 小林, 達伺
  organization: 筑波大学基礎医学系病理
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DocumentTitleAlternate Progression of atherosclerosis and macrophage/lympho-cytes. Implication of adhesion molecules ICAM-1/LFA-1 and MMP-12 in lesion development
DocumentTitle_FL Progression of atherosclerosis and macrophage/lympho-cytes. Implication of adhesion molecules ICAM-1/LFA-1 and MMP-12 in lesion development
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References 1) Watanabe T, Haraoka S, and Shimokama T: Inflammatory and immunological nature of atherosclerosis. Int J Cardiol, 54(Suppl): S25-S34, 1996
8) Li Z, Li L, Zielke R, Chang L, Xiao R, Crow MT, Stetler-Stevenson WG, Froehlich J, and Lakatta EG: Increased expression of 72-kd type IV collagenase (MMP-2) in human aortic atherosclerotic lesions. Am J Pathol, 148: 121-128, 1996
13) Galis ZS, Sukhova GK, Kranzhöfer R, Clark S, and Libby P: Macrophage foam cells from experimental atheroma constitutively produce matrix-degrading proteinases. Proc Natl Acad Sci USA, 92: 402-406, 1995
5) Haraoka S, Shimokama T, and Watanabe T: Participation of T lymphocytes in atherogenesis: sequential and quantitative observation of aortic lesions of rats with diet-induced hypercholesterolemia using en face double immunostaining. Virchows Arch, 426: 308-315, 1995
12) Chandler S, Cossin J, Lury J, and Wells G: Macrophage metalloelastase degrades matrix and myelin proteins and processes a tumor necrosis factor-a fusion protein. Biochem Biophys Res Commun, 228: 421-429, 1996
2) Carlos TM and Harlan JM: Leukocyte-endothelial adhesion molecule. Blood, 84: 2068-2101, 1994
11) Shapiro SD, Kobayashi DK, and Ley TJ: Cloning and characterization of a unique elastolytic metalloproteinase produced by human alveolar macrophages. J Biol Chem, 268: 23824-23829, 1993
10) Matsumoto S, Kobayashi T, Katoh M, Saito S, Ikeda Y, Kobori M, Masuho Y, and Watanabe T: Expression and localization of matrix metalloproteinase-12 in the aorta of cholesterol-fed rabbits: relationship to lesion development. Am J Pathol, 153: 109-119, 1998
9) Katsuda S, Okada Y, Okada Y, Imai K, and Nakanishi I: Matrix metalloproteinase-9 (92-kd gelatinase/type IV collagenase equals gelatinase B) can degrade arterial elastin. Am J Pathol, 145: 1208-1218, 1994
3) Cybulsky MI and Gimbrone MAJr: Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. Science, 251: 788-791, 1991
4) van der Wal AC, Das PK, Tiggers AJ, and Becker AE: Adhesion molecules on the endothelium and mononuclear cells in human atherosclerotic lesions. Am J Pathol, 141: 1427-1433, 1992
6) Nie Q, Fan J, Haraoka S, Shimokama T, and Watanabe T: Inhibition of mononuclear cell recruitment in aortic intima by treatment with anti-ICAM-1 and anti-LFA-1 monoclonal antibodies in hypercholesterolemic rats: Implication of the ICAM-1 and LFA-1 pathway in atherogenesis. Lab Invest, 77: 469-488, 1997
7) Kume N, Cybulsky MI, and Gimbrone MA: Lysophosphatidylcholine, a component of atherogenic lipoproteins, induces mononuclear leukocyte adhesion molecules in cultured human and rabbit arterial endothelial cells. J Clin Invest, 90: 1138-1144, 1992
References_xml – reference: 2) Carlos TM and Harlan JM: Leukocyte-endothelial adhesion molecule. Blood, 84: 2068-2101, 1994
– reference: 9) Katsuda S, Okada Y, Okada Y, Imai K, and Nakanishi I: Matrix metalloproteinase-9 (92-kd gelatinase/type IV collagenase equals gelatinase B) can degrade arterial elastin. Am J Pathol, 145: 1208-1218, 1994
– reference: 12) Chandler S, Cossin J, Lury J, and Wells G: Macrophage metalloelastase degrades matrix and myelin proteins and processes a tumor necrosis factor-a fusion protein. Biochem Biophys Res Commun, 228: 421-429, 1996
– reference: 1) Watanabe T, Haraoka S, and Shimokama T: Inflammatory and immunological nature of atherosclerosis. Int J Cardiol, 54(Suppl): S25-S34, 1996
– reference: 10) Matsumoto S, Kobayashi T, Katoh M, Saito S, Ikeda Y, Kobori M, Masuho Y, and Watanabe T: Expression and localization of matrix metalloproteinase-12 in the aorta of cholesterol-fed rabbits: relationship to lesion development. Am J Pathol, 153: 109-119, 1998
– reference: 11) Shapiro SD, Kobayashi DK, and Ley TJ: Cloning and characterization of a unique elastolytic metalloproteinase produced by human alveolar macrophages. J Biol Chem, 268: 23824-23829, 1993
– reference: 13) Galis ZS, Sukhova GK, Kranzhöfer R, Clark S, and Libby P: Macrophage foam cells from experimental atheroma constitutively produce matrix-degrading proteinases. Proc Natl Acad Sci USA, 92: 402-406, 1995
– reference: 7) Kume N, Cybulsky MI, and Gimbrone MA: Lysophosphatidylcholine, a component of atherogenic lipoproteins, induces mononuclear leukocyte adhesion molecules in cultured human and rabbit arterial endothelial cells. J Clin Invest, 90: 1138-1144, 1992
– reference: 4) van der Wal AC, Das PK, Tiggers AJ, and Becker AE: Adhesion molecules on the endothelium and mononuclear cells in human atherosclerotic lesions. Am J Pathol, 141: 1427-1433, 1992
– reference: 5) Haraoka S, Shimokama T, and Watanabe T: Participation of T lymphocytes in atherogenesis: sequential and quantitative observation of aortic lesions of rats with diet-induced hypercholesterolemia using en face double immunostaining. Virchows Arch, 426: 308-315, 1995
– reference: 3) Cybulsky MI and Gimbrone MAJr: Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. Science, 251: 788-791, 1991
– reference: 6) Nie Q, Fan J, Haraoka S, Shimokama T, and Watanabe T: Inhibition of mononuclear cell recruitment in aortic intima by treatment with anti-ICAM-1 and anti-LFA-1 monoclonal antibodies in hypercholesterolemic rats: Implication of the ICAM-1 and LFA-1 pathway in atherogenesis. Lab Invest, 77: 469-488, 1997
– reference: 8) Li Z, Li L, Zielke R, Chang L, Xiao R, Crow MT, Stetler-Stevenson WG, Froehlich J, and Lakatta EG: Increased expression of 72-kd type IV collagenase (MMP-2) in human aortic atherosclerotic lesions. Am J Pathol, 148: 121-128, 1996
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SubjectTerms Adhesion molecules
Atherosclerosis
Hyper lipidemia
Macro-phage
Matrix metalloprotease
Subtitle 特に接着蛋白ICAM-1/LFA-1とMMP-12の関わり
Title マクロファージ・リンパ球と動脈硬化の進展
URI https://www.jstage.jst.go.jp/article/jat1973/26/4-5/26_4-5_173/_article/-char/ja
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