ジゴキシンの正常心に対する陽性変力効果:安静時ならびに運動時左心機能の心エコー図ならびに心機図による検討

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Published inJAPANESE CIRCULATION JOURNAL Vol. 43; no. SUPPLEMENT-I; pp. 25 - 34
Main Authors 岡元, 政和, 田中, 弘光, 斉藤, 和人, 鹿島, 友義, 金久, 卓也
Format Journal Article
LanguageEnglish
Published 社団法人 日本循環器学会 20.12.1979
Online AccessGet full text
ISSN0047-1828
1347-4839
DOI10.1253/jcj.43.SUPPLEMENT-I_25

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Author 鹿島, 友義
岡元, 政和
斉藤, 和人
田中, 弘光
金久, 卓也
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References 14) Fortuin, N.J. & Pawsey, C.G.K.: The evaluation of left ventricular function by echocardiography. Am. J. Med. 63: 1, 1977.
17) Stein, R.A., Michielli, D., Fox, E.L. & Krasnow, N.: Continuous ventricular dimensions in man during supine exercise and recovery-An echocardiographic study. Am. J. Cardiol. 41: 655, 1978.
24) Mahler, F.Y.C. & Ross, J.J.: Inotropic effect of tachycardia and poststimulation potentiation in the conscious dog. Am. J. Physiol. 227: 569, 1974.
13) Hirshleifer, J., Crawford, M., O'Rourke, R.A. & Kerliner, J.S.: Influence of acute alterations of heart rate and systemic arterial pressure on echocardiographic measures of left ventricular performance in normal subjects. Circulation. 52: 835, 1975.
8) Saito, K., Tanaka, H., Okamoto, M., Kashima, T. & Kanehisa, T.: Positive inotropic action of oral administration of digoxin on the normal heart. Igaku. no. Ayumi. 105: 662, 1978.
23) Shudo, I.: Relationship between arrhythmias and a liberation of endogeneous catecholamine caused by toxic dose of ouabain in dogs. J. Toxicol. Sci. 2: 239, 1977.
6) Crawford, M.H., Karliner, J.S. & O'Rourke, R.A.: Favorable effects of oral maintenance digoxin therapy on left ventricular performance in normal subjects: Echocardiographic Study. Am. J. Caydiol. 38: 843, 1976.
2) Mason, D.T. & Braunwald, E.: Studies on digitalis. IX. Effects of Ouabain on the non-failing human heart. J. Clin. Invest. 42: 1105, 1963.
15) Lewis, R.P., Rittgers, S.E., Forester, W.F. & Bouduulas, H.: A critical review of the systolic time intervals. Circulation. 56: 146, 1977.
19) Saito, K., Kashima, T., Okamoto, M., Tanaka, H., & Kanehisa, T.: The effect of digoxin on the normal heart. Presented at the 43th Kyushu regional meeting of the Japanese Circulation Society. December, 1977.
21) Ross, J., Braunwald, E. & Waldhausen, J.A.: Studies on digitalis. II. Extracardiac effects on venous return and on the capacity of the peripheral vescular bed. J. Clin. Invest. 39: 937, 1960.
3) Williams, H., Zohman, L.R. & Ratner, A.C.: Hemodynamic effects of cardiac glycosides on normal human subjects during rest and exercise. J. Appl. Physiol. 13: 417, 1958.
12) Quinones, M.A., Gaasch, W.H. & Alexander, J.K.: Echocardiographic assessment of left ventricualr function. Circulation. 50: 42, 1974.
16) Vatner, S.F. & Pagani, M.: Cardiovascular ajustments to exerciie: Hemodynamics and mechanisms. Prog. Cardiovas. Dis. 19: 91, 1976.
7) Schinz, A., Schnelle, K., Klein, G. & Blomer, H.: Time sequence of direct vascular and inotropic effects following intravenous administration of digoxin in normal man. Int. J. Clin. Pharmacol. 15: 189, 1977.
9) Weissler, A.M., Harris, W.S. & Schoenfeld, C.D.: Bedside technics for the evaluation of ventricular function in man. Am. J. Cardiol. 23: 576, 1969.
20) Ross, J., Waldhausen J.A. & Braunwald, E.: Studies on digitalis. I. Direct effects on peripheral vascular resistance. J. Clin. Invest. 39: 930, 1960.
1) Braunwald, E., Bloodwell, R.D., Goldberg, L.I. & Morrow, A.G.: Studies on digitalis. IV. Observations in man on the effects of digitalis preparations on the contractilility of the non-failing heart and on total vascular resistance. J. Clin. Invest. 40: 52, 1961.
4) Rodman, T., Gorczyca, C.A. & Pastor, B.H.: The effect of digitalis on the cardiac output of the normal at rest and during exercise Ann. Int. Med. 55: 620, 1961.
22) Mason, D.T., Spann, J.F. & Zelis, R.: New developments in the understanding of the actions of the digitalis glycosides. Prog. Cardiovas. Dis. 11: 443, 1969.
5) Weissler, A.M., & Schoenfeld, C.D.: Effect of digitalis on systolic time intervals in heart failure. Am. J. Med. Sci. 259: 4, 1970.
10) Lewis, R.P. & Sandler, H.: Relationship between changes in left ventricular dimensions and the ejection fraction in man. Circulation. 44: 548, 1971.
11) Cooper, R.H., O'Rourke, R.A., Karliner, J.S., Peterson, K.L. & Leopold, G.R.: Comparison of ultrasound and cineangiographic measurements of the mean rate of circumferential fiber shortening in man. Circulation. 46: 914, 1972.
18) Williams, J.F., Klocke, J.F. J. & Braunwald, E.: Studies on digitalis XIII. A comparison of the effects of potassium on the inotropic and arrhyth mia-producing actions of ouabain. J. Clin. Invest. 45: 346, 1966.
References_xml – reference: 3) Williams, H., Zohman, L.R. & Ratner, A.C.: Hemodynamic effects of cardiac glycosides on normal human subjects during rest and exercise. J. Appl. Physiol. 13: 417, 1958.
– reference: 20) Ross, J., Waldhausen J.A. & Braunwald, E.: Studies on digitalis. I. Direct effects on peripheral vascular resistance. J. Clin. Invest. 39: 930, 1960.
– reference: 24) Mahler, F.Y.C. & Ross, J.J.: Inotropic effect of tachycardia and poststimulation potentiation in the conscious dog. Am. J. Physiol. 227: 569, 1974.
– reference: 5) Weissler, A.M., & Schoenfeld, C.D.: Effect of digitalis on systolic time intervals in heart failure. Am. J. Med. Sci. 259: 4, 1970.
– reference: 23) Shudo, I.: Relationship between arrhythmias and a liberation of endogeneous catecholamine caused by toxic dose of ouabain in dogs. J. Toxicol. Sci. 2: 239, 1977.
– reference: 6) Crawford, M.H., Karliner, J.S. & O'Rourke, R.A.: Favorable effects of oral maintenance digoxin therapy on left ventricular performance in normal subjects: Echocardiographic Study. Am. J. Caydiol. 38: 843, 1976.
– reference: 10) Lewis, R.P. & Sandler, H.: Relationship between changes in left ventricular dimensions and the ejection fraction in man. Circulation. 44: 548, 1971.
– reference: 4) Rodman, T., Gorczyca, C.A. & Pastor, B.H.: The effect of digitalis on the cardiac output of the normal at rest and during exercise Ann. Int. Med. 55: 620, 1961.
– reference: 17) Stein, R.A., Michielli, D., Fox, E.L. & Krasnow, N.: Continuous ventricular dimensions in man during supine exercise and recovery-An echocardiographic study. Am. J. Cardiol. 41: 655, 1978.
– reference: 18) Williams, J.F., Klocke, J.F. J. & Braunwald, E.: Studies on digitalis XIII. A comparison of the effects of potassium on the inotropic and arrhyth mia-producing actions of ouabain. J. Clin. Invest. 45: 346, 1966.
– reference: 21) Ross, J., Braunwald, E. & Waldhausen, J.A.: Studies on digitalis. II. Extracardiac effects on venous return and on the capacity of the peripheral vescular bed. J. Clin. Invest. 39: 937, 1960.
– reference: 7) Schinz, A., Schnelle, K., Klein, G. & Blomer, H.: Time sequence of direct vascular and inotropic effects following intravenous administration of digoxin in normal man. Int. J. Clin. Pharmacol. 15: 189, 1977.
– reference: 1) Braunwald, E., Bloodwell, R.D., Goldberg, L.I. & Morrow, A.G.: Studies on digitalis. IV. Observations in man on the effects of digitalis preparations on the contractilility of the non-failing heart and on total vascular resistance. J. Clin. Invest. 40: 52, 1961.
– reference: 9) Weissler, A.M., Harris, W.S. & Schoenfeld, C.D.: Bedside technics for the evaluation of ventricular function in man. Am. J. Cardiol. 23: 576, 1969.
– reference: 14) Fortuin, N.J. & Pawsey, C.G.K.: The evaluation of left ventricular function by echocardiography. Am. J. Med. 63: 1, 1977.
– reference: 13) Hirshleifer, J., Crawford, M., O'Rourke, R.A. & Kerliner, J.S.: Influence of acute alterations of heart rate and systemic arterial pressure on echocardiographic measures of left ventricular performance in normal subjects. Circulation. 52: 835, 1975.
– reference: 8) Saito, K., Tanaka, H., Okamoto, M., Kashima, T. & Kanehisa, T.: Positive inotropic action of oral administration of digoxin on the normal heart. Igaku. no. Ayumi. 105: 662, 1978.
– reference: 19) Saito, K., Kashima, T., Okamoto, M., Tanaka, H., & Kanehisa, T.: The effect of digoxin on the normal heart. Presented at the 43th Kyushu regional meeting of the Japanese Circulation Society. December, 1977.
– reference: 11) Cooper, R.H., O'Rourke, R.A., Karliner, J.S., Peterson, K.L. & Leopold, G.R.: Comparison of ultrasound and cineangiographic measurements of the mean rate of circumferential fiber shortening in man. Circulation. 46: 914, 1972.
– reference: 2) Mason, D.T. & Braunwald, E.: Studies on digitalis. IX. Effects of Ouabain on the non-failing human heart. J. Clin. Invest. 42: 1105, 1963.
– reference: 12) Quinones, M.A., Gaasch, W.H. & Alexander, J.K.: Echocardiographic assessment of left ventricualr function. Circulation. 50: 42, 1974.
– reference: 15) Lewis, R.P., Rittgers, S.E., Forester, W.F. & Bouduulas, H.: A critical review of the systolic time intervals. Circulation. 56: 146, 1977.
– reference: 22) Mason, D.T., Spann, J.F. & Zelis, R.: New developments in the understanding of the actions of the digitalis glycosides. Prog. Cardiovas. Dis. 11: 443, 1969.
– reference: 16) Vatner, S.F. & Pagani, M.: Cardiovascular ajustments to exerciie: Hemodynamics and mechanisms. Prog. Cardiovas. Dis. 19: 91, 1976.
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Title ジゴキシンの正常心に対する陽性変力効果:安静時ならびに運動時左心機能の心エコー図ならびに心機図による検討
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