A CHILD CASE OF ACUTE MYELOID LEUKEMIA WITH GRANULOCYTIC SARCOMA

An 8-year-old boy was admitted to our hospital because of pain and muscle weakness of the right lower extremity, back pain, dysuria. A magnetic resonance imaging examination demonstrated a mass in his pelvic cavity. A diagnosis of acute myeloid leukemia (the French-American-British M 2 subtype) with...

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Published inJapanese Journal of National Medical Services Vol. 51; no. 10; pp. 486 - 489
Main Authors KOYAMA, Teruhisa, KANADANI, Tomohisa, SUENAGA, Atsushi, NAKAHARA, Shinnosuke, MURAKAMI, Motomasa
Format Journal Article
LanguageJapanese
Published Japanese Society of National Medical Services 1997
Subjects
acute myeloid leukemia
granulocytic sarcoma
unrelated bone marrow transplantation
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Summary:An 8-year-old boy was admitted to our hospital because of pain and muscle weakness of the right lower extremity, back pain, dysuria. A magnetic resonance imaging examination demonstrated a mass in his pelvic cavity. A diagnosis of acute myeloid leukemia (the French-American-British M 2 subtype) with granulocytic sarcoma was made by a peripheral blood and bone marrow examination. A cytogenetic study of bone marrow cells revealed an abnormal clone with a karyotype 45, X, -Y, t (8;21). Induction chemotherapy was initiated and he was successfully induced to complete remission, however, he had a relapse in the bone marrow and in the pelvic cavity 11 months later. Because there were no HLA-matched siblings, he was referred to another hospital for unrelated donor bonc marrow transplantation.
ISSN:0021-1699
1884-8729
DOI:10.11261/iryo1946.51.486