Sarcoidosis with Recurrent Renal Dysfunction and Hypercalcemia
A case of sarcoidosis with calcium nephropathy is reported. A 62 year-old-female was admitted in September, 1996, when she had fever, renal dysfunction, hypercalcemia, abnormal X-ray findings and body weight loss. At admission, sarcoidosis was diagnosed because of TBLB finding of non-caseous epithel...
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| Published in | NIHON SARUKOIDOSHISU / NIKUGESHUSHIKKAN (The Japanese journal of sarcoidosis and other granulomatous disorders ) Vol. 19; no. 1; pp. 81 - 85 |
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| Main Author | |
| Format | Journal Article |
| Language | Japanese |
| Published |
Japan Society of Sarcoidosis and other Granulomatous Disorders
1999
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| Subjects | |
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| Abstract | A case of sarcoidosis with calcium nephropathy is reported. A 62 year-old-female was admitted in September, 1996, when she had fever, renal dysfunction, hypercalcemia, abnormal X-ray findings and body weight loss. At admission, sarcoidosis was diagnosed because of TBLB finding of non-caseous epithelioid cell granuloma, negative tuberculin test, iritis with secondary glaucoma and elevated level of serum γ-globulin. Hypercalcemia and renal dysfunction improved after six days of admission with no particular treatment. Renal biopsy showed intact glomeruli, interstitial fibrosis. After discharge she had two episodes of hypercalcemia and renal dysfunction. Each renal biopsy revealed interstitial fibrosis, small granuloma near-by tubules and calcium deposit. Improvement of both hypercalcemia and renal dysfunction was obtained by only bed rest. |
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| AbstractList | A case of sarcoidosis with calcium nephropathy is reported. A 62 year-old-female was admitted in September, 1996, when she had fever, renal dysfunction, hypercalcemia, abnormal X-ray findings and body weight loss. At admission, sarcoidosis was diagnosed because of TBLB finding of non-caseous epithelioid cell granuloma, negative tuberculin test, iritis with secondary glaucoma and elevated level of serum γ-globulin. Hypercalcemia and renal dysfunction improved after six days of admission with no particular treatment. Renal biopsy showed intact glomeruli, interstitial fibrosis. After discharge she had two episodes of hypercalcemia and renal dysfunction. Each renal biopsy revealed interstitial fibrosis, small granuloma near-by tubules and calcium deposit. Improvement of both hypercalcemia and renal dysfunction was obtained by only bed rest. |
| Author | Sezaki, Ryozo |
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| DOI | 10.14830/jssog1999.19.81 |
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| References | 10) 千葉弘文, 黒川慶三, 森 裕二 他: 高カルシウム血症を呈したサルコイドーシスの一例. 道南医学会誌 1991; 30: 284-286. 13) 椎木智子, 北川隆夫, 中村寿宏 他: 著明な高カルシウム血症を合伴したサルコイドーシスの一例. 高知市医誌 1997; 2: 81-84. 14) 梶川麻里子, 倉八博之: 著明な高カルシウム血症と尿路結石症を随伴した非典型サルコイドーシスの一例. Clinical Calcium 1997; 7: 1251-1254. 2) 池田健次, 二瓶 宏, 青山温子 他: 季節的変動を伴う高カルシウム血症を示したサルコイドーシスの一例. 日内会誌 1983; 72: 925-931. 5) 戸沢雅彦, 当麻茂樹, 照喜名重一 他: Elcatonin治療により腎機能が回復した高カルシウム血症を伴うサルコイドーシスの一例. 内科 1991; 68: 957-959. 12) 谷野功典, 横内 浩, 小笠原英紀 他: 腎病変を伴ったサルコイドーシスの一例. 旭市病誌 1996; 28: 60-64. 17) 長谷川みどり, 浅野慎介, 好村栄子 他: 急速な腎機能障害を契機に診断されたサルコイドーシスの一例. 日腎誌 1997; 39: 563. 15) 奥田日実子, 田村博之, 寺田典生 他: 肉芽腫の浸潤による腎不全と著明な高Ca血症をきしたサルコイドーシスの一例. 日腎誌 1997; 39: 75. 8) Rikitake Y, Kinosita Y, Kotani Y et al: Sarcoidosis with hypercalcemia-successful treatment of renal insufficiency and renal calcification with prednisolon. Int Med 1994; 33: 222-225. 4) 小久保透, 堀井 昭, 洞田映子 他: サルコイドーシスにより高Ca血症を来した慢性腎不全の一例. 臨体液 1991; 18: 161-65. 6) 布広龍也, 青井 渉, 門田淳一 他: 高Ca血症, 尿路結石, Nephrocalcinosis, 腎機能障害を呈したサルコイドーシスの一例 日腎誌 1992; 19: 959-964. 11) 藤田 明, 鈴木 光, 樫山鉄矢 他: 高カルシウム血症を合伴したサルコイドーシスの一例-肺組織中の1α, 25-dihydroxyvitamin D含量増加について. 日胸疾会誌 1995; 33: 900-905. 9) 岡本傳男, 香川幸司, 漆谷義徳 他: サ症の経過観察中に肉芽腫形成性間質性腎炎と高カルシウム血症を併発した一例 松江赤十字病院医誌 1994; 6: 28-32. 7) 篠崎一哉, 古家大祐, 阪本勝彦 他: 著明な高Ca血症を呈した肺サルコイドーシスの一例. 日内分泌会誌 1994; 70: 503-510. 16) 戸田孝之, 木本成昭, 西尾康英 他: 腎機能障害を呈し, 腎生検で肉芽腫を伴う間質性腎炎を認めたサルコイドーシスの一例. 日腎誌 1997; 39: 75. 1) Muther RS, McCarron DA, Rennet WM: Renal manifestation of sarcoidosis. Arch Intern Med 1981; 141: 643-645. 3) 清水伸一, 深瀬正晃, 藤田卓夫 他: 腎不全を伴う高カルシウム血症を示した筋サルコイドーシスの一例. 日内会誌 1985; 74: 473-479. |
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| SubjectTerms | Calcium nephropathy Hypercalcemia Renal dysfunction Sarcoidosis |
| Title | Sarcoidosis with Recurrent Renal Dysfunction and Hypercalcemia |
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