Changes of lymphocrte function in obstructive jaundiced states

• Published in: Tando Vol. 6; no. 1; pp. 45 - 53
• Main Authors: KATO, Fumihiko, AKAMO, Yoshimi, MURAMOTO, Masayuki, TAKAOKA, Tetsuro, FUKUI, Takuji, SHIBATA, Kiyohito
• Format: Journal Article
• Language: Japanese
• Published: Japan Biliary Association 1992
• Subjects: リンパ球幼若化反応; リンパ球幼若化反応抑制因子; 減黄処置; 閉塞性黄疸
• ISSN: 0914-0077; 1883-6879
• DOI: 10.11210/tando1987.6.1_45

A clinical and exprimental evaluation on lymphocyte transformation ability under jaundiced state, and the effect of serum obtained from jaundiced subjects were performed, giving the following results. 1) the lymphocyte's transformation ability was proven to be decreased at jaundiced states both clinically and experimentally. 2) The serum obtained from jaundiced subjects, proved to contain an inhibitory substance against lymphocyte transformation. These results indicate that the reduction of the level of hyperbilirubinemia, is of value in terms of improving the patients'immunological strength, especially the lymphocyte's power.