抗酸菌感染症はなぜ難治性なのか 動物実験モデルでの成績からの考察
Saved in:
| Published in | 日本ハンセン病学会雑誌 Vol. 65; no. 3; pp. 155 - 165 |
|---|---|
| Main Author | |
| Format | Journal Article |
| Language | Japanese |
| Published |
日本ハンセン病学会
30.11.1996
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 1342-3681 1884-314X |
| DOI | 10.5025/hansen.65.155 |
Cover
| Author | 冨岡, 治明 |
|---|---|
| Author_xml | – sequence: 1 fullname: 冨岡, 治明 organization: 島根医科大学 |
| BookMark | eNo9jz1Lw0AAhg-pYK0d_RlX7_tjlGJVKLgouB2X3J1NqFGSLm4GFEEFB4cOCh0cBAcFJ8GfE4j2X1iMuLwf8PLCswpa2UnmAVjHqMcR4RsjmxU-6wnew5wvgTZWikGK2WFrkSkjkAqFV0C3KJIIISkFEZS1Aayvp_PLj--72_piVs_uv6ZXVflWlS9V-Th_eKrfP-vz59_6WpU3a2A52HHhu3_eAQeDrf3-Dhzube_2N4cwxURbqKT2WkYiDj6KMfVIO8dR0EGEIK0kTDvMnZPIKqoQjpCklKDASLAkcoTSDhg0v2kxsUfenObJsc3PjM0nSTz2poHFWgsjuKGNLLj_B_HI5ia19AeVx2LW |
| ContentType | Journal Article |
| Copyright | 日本ハンセン病学会 |
| Copyright_xml | – notice: 日本ハンセン病学会 |
| DOI | 10.5025/hansen.65.155 |
| DeliveryMethod | fulltext_linktorsrc |
| EISSN | 1884-314X |
| EndPage | 165 |
| ExternalDocumentID | article_hansen1996_65_3_65_3_155_article_char_ja |
| GroupedDBID | --- 2WC 5GY ALMA_UNASSIGNED_HOLDINGS F5P JSF KQ8 RJT |
| ID | FETCH-LOGICAL-j129a-879e97b6cfebc13e09dd50f9f6ff7a7249d15dd70a83801b073320f42fa2bd233 |
| ISSN | 1342-3681 |
| IngestDate | Wed Sep 03 06:22:21 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | false |
| IsScholarly | true |
| Issue | 3 |
| Language | Japanese |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-j129a-879e97b6cfebc13e09dd50f9f6ff7a7249d15dd70a83801b073320f42fa2bd233 |
| OpenAccessLink | https://www.jstage.jst.go.jp/article/hansen1996/65/3/65_3_155/_article/-char/ja |
| PageCount | 11 |
| ParticipantIDs | jstage_primary_article_hansen1996_65_3_65_3_155_article_char_ja |
| PublicationCentury | 1900 |
| PublicationDate | 1996/11/30 |
| PublicationDateYYYYMMDD | 1996-11-30 |
| PublicationDate_xml | – month: 11 year: 1996 text: 1996/11/30 day: 30 |
| PublicationDecade | 1990 |
| PublicationTitle | 日本ハンセン病学会雑誌 |
| PublicationTitleAlternate | 日ハンセン病会誌 |
| PublicationYear | 1996 |
| Publisher | 日本ハンセン病学会 |
| Publisher_xml | – name: 日本ハンセン病学会 |
| References | 12) Kanai, K. and Kondo, K.: Antibacterial and cytoxic aspects of long chain fatty acids as cell surface events: selected topics. Jpn. J. Med. Sci. Biol. 32:135-174 (1979). 17) 冨岡治明:Mycobacterium intracellulare感染マウスに誘導される免疫抑制性マクロファーDジの性状.結核68:767-775(1993). 11) Tomioka, H. and Saito, H.: Macrophage chemiluminescence induced by interaction with transparent and opaquecolonial variants of Mycobacterium intracellulare. J. Gen. Microbiol. 139: 3011-3015 (1993). 18) Tomioka, H., Sato K., Maw, W. W., et al.: The role of tumor necrosis factor, interferon-γ, transforming growth factor-β, and nitric oxide in the expression of immunosuppressive functions of splenic macrophages induced by Mycobacterium avium complex infection. J. Leuk. Biol. 58:704-712 (1995). 2) Trinchieri, G.: Interleukin-12 and its role in the generation of TH-1 cells. Immunol. Today 14:335-337 (1993). 8) Chan, J. , Xing, Y., Magliozzo, R. S., et al.: Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages. J. Exp. Med. 175: 1111-1122 (1992) . 9) Yamada, Y. , Saito, H. , Tomioka, Jpn. J. Leprosy 65, 155-165(1996) H., et al.: Susceptibility of microorgan-isms to active oxygen species: Sensitivity to the xanthine-oxidase-mediated antimicrobial system. J. Gen. Mi-crobiol. 133:2007-2014 (1987). 20) Tomioka, H., Kishimoto, T., and Maw, W. W.: Phospholipids and reactive nitrogen intermediates collaborate in expression of the T cell mitogenesis-inhibitory activity of immunosuppressive macrophages induced in mycobacterial infection. Clin. Exp. Immunol. 103:219-225(1996). 16) Tomioka, H , and Saito, H.: Characterization of immunosuppressive functions of murine peritoneal macrophages induced with various agents. J. Leuk. Biol. 51: 24-31 (1992). 13) Saito, H. and Tomioka, H.: Susceptibiltiy of transparent, opaque, and rough colonial variants of Mycobacteriumavium complex to various fatty acids. Antimicrob. Agents Chemother. 32:400-402 (1988) . 10) Yamada, Y., Saito, H., Tomioka, H., et al.: Relationship between the susceptibility of various bacteria to active oxygen species and to intracellulare killing by macrophages. J. Gen. Microbiol. 133:2015-2021(1987). 1) 冨岡治明:抗酸菌感染症が難治性である理由を探る.日本細菌学雑誌,50:687-701(1995). 19) Tomioka, H., Maw, W. W., Sato, K., et al.: The role of tumor necrosis factor-α in combination with interferon-γ or iriterleukin-1 in the induction of immunosuppressive macrophages due to Mycobacterium avium complex infection. Immunology 88:61-67 (1996). 4) Mosmann, T. R. and Moore, K. W.: The role of IL-10 in crossregulation of TH1 and TH2 responses. Immunol. Today 12:A49-53 (1991). 14) Tomioka, H., Saito, H., and Yamada, Y.: Characteristics of immunosuppressive macrophages induced in spleen cells by Mycobacterium avium complex infections in mice. J. Gen. Microbiol. 136:965-973 (1990). 15) Tomioka, H., Saito, H., and Sato, K.: Characterization of immunosuppressive macrophages induced in host spleen cells by Mycobacterium avium complex and Mycobacterium tuberculosis infections in mice. Microbiol. Immunol. 34:283-297, (1990). 6) Bermudez, L. E. and Champsi, J. A.: Infection with Mycobacterium avium induced production of interleukin-10 (IL-10), and administration of anti-IL-10 antibody is associated with enhanced resistance to infection in mice. Infect. Immun. 61:3093-3097 (1993). 3) Castro, A. G . , Silva , R. A. , and Appelberg, R.: Endogenously produced IL-12 is required for the induction of protective T cells during Mycobacterium avium infections in mice. J. Immunol. 155: 2013-2019 (1995). 5) Bermudez, L. E.: Production of transforming growth factor -β by Mycobacterium avium-infected human macrophagesis associated with unresponsiveness to IFN-γ . J. Immunol. 150:1838-1845 (1993). 7) Chan, J. and Kauf mann , H. E.: Immune mechanisms of protection. In: Tuberculosis. Pathogenesis, Protection,and Control. (ed by B. R. Bloom) p. 389-415, ASM Press, Washington, DC. (1994). |
| References_xml | – reference: 16) Tomioka, H , and Saito, H.: Characterization of immunosuppressive functions of murine peritoneal macrophages induced with various agents. J. Leuk. Biol. 51: 24-31 (1992). – reference: 2) Trinchieri, G.: Interleukin-12 and its role in the generation of TH-1 cells. Immunol. Today 14:335-337 (1993). – reference: 7) Chan, J. and Kauf mann , H. E.: Immune mechanisms of protection. In: Tuberculosis. Pathogenesis, Protection,and Control. (ed by B. R. Bloom) p. 389-415, ASM Press, Washington, DC. (1994). – reference: 20) Tomioka, H., Kishimoto, T., and Maw, W. W.: Phospholipids and reactive nitrogen intermediates collaborate in expression of the T cell mitogenesis-inhibitory activity of immunosuppressive macrophages induced in mycobacterial infection. Clin. Exp. Immunol. 103:219-225(1996). – reference: 10) Yamada, Y., Saito, H., Tomioka, H., et al.: Relationship between the susceptibility of various bacteria to active oxygen species and to intracellulare killing by macrophages. J. Gen. Microbiol. 133:2015-2021(1987). – reference: 15) Tomioka, H., Saito, H., and Sato, K.: Characterization of immunosuppressive macrophages induced in host spleen cells by Mycobacterium avium complex and Mycobacterium tuberculosis infections in mice. Microbiol. Immunol. 34:283-297, (1990). – reference: 5) Bermudez, L. E.: Production of transforming growth factor -β by Mycobacterium avium-infected human macrophagesis associated with unresponsiveness to IFN-γ . J. Immunol. 150:1838-1845 (1993). – reference: 8) Chan, J. , Xing, Y., Magliozzo, R. S., et al.: Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages. J. Exp. Med. 175: 1111-1122 (1992) . – reference: 3) Castro, A. G . , Silva , R. A. , and Appelberg, R.: Endogenously produced IL-12 is required for the induction of protective T cells during Mycobacterium avium infections in mice. J. Immunol. 155: 2013-2019 (1995). – reference: 13) Saito, H. and Tomioka, H.: Susceptibiltiy of transparent, opaque, and rough colonial variants of Mycobacteriumavium complex to various fatty acids. Antimicrob. Agents Chemother. 32:400-402 (1988) . – reference: 18) Tomioka, H., Sato K., Maw, W. W., et al.: The role of tumor necrosis factor, interferon-γ, transforming growth factor-β, and nitric oxide in the expression of immunosuppressive functions of splenic macrophages induced by Mycobacterium avium complex infection. J. Leuk. Biol. 58:704-712 (1995). – reference: 4) Mosmann, T. R. and Moore, K. W.: The role of IL-10 in crossregulation of TH1 and TH2 responses. Immunol. Today 12:A49-53 (1991). – reference: 6) Bermudez, L. E. and Champsi, J. A.: Infection with Mycobacterium avium induced production of interleukin-10 (IL-10), and administration of anti-IL-10 antibody is associated with enhanced resistance to infection in mice. Infect. Immun. 61:3093-3097 (1993). – reference: 19) Tomioka, H., Maw, W. W., Sato, K., et al.: The role of tumor necrosis factor-α in combination with interferon-γ or iriterleukin-1 in the induction of immunosuppressive macrophages due to Mycobacterium avium complex infection. Immunology 88:61-67 (1996). – reference: 9) Yamada, Y. , Saito, H. , Tomioka, Jpn. J. Leprosy 65, 155-165(1996) H., et al.: Susceptibility of microorgan-isms to active oxygen species: Sensitivity to the xanthine-oxidase-mediated antimicrobial system. J. Gen. Mi-crobiol. 133:2007-2014 (1987). – reference: 1) 冨岡治明:抗酸菌感染症が難治性である理由を探る.日本細菌学雑誌,50:687-701(1995). – reference: 12) Kanai, K. and Kondo, K.: Antibacterial and cytoxic aspects of long chain fatty acids as cell surface events: selected topics. Jpn. J. Med. Sci. Biol. 32:135-174 (1979). – reference: 11) Tomioka, H. and Saito, H.: Macrophage chemiluminescence induced by interaction with transparent and opaquecolonial variants of Mycobacterium intracellulare. J. Gen. Microbiol. 139: 3011-3015 (1993). – reference: 17) 冨岡治明:Mycobacterium intracellulare感染マウスに誘導される免疫抑制性マクロファーDジの性状.結核68:767-775(1993). – reference: 14) Tomioka, H., Saito, H., and Yamada, Y.: Characteristics of immunosuppressive macrophages induced in spleen cells by Mycobacterium avium complex infections in mice. J. Gen. Microbiol. 136:965-973 (1990). |
| SSID | ssib007762634 ssib000872007 ssib009993785 ssib003171060 ssj0000602612 ssib058493798 ssib005902204 |
| Score | 1.4480203 |
| SourceID | jstage |
| SourceType | Publisher |
| StartPage | 155 |
| SubjectTerms | マクロファージ 免疫抑制性マクロファージはじめに 抗酸菌 殺菌メカニズム |
| Subtitle | 動物実験モデルでの成績からの考察 |
| Title | 抗酸菌感染症はなぜ難治性なのか |
| URI | https://www.jstage.jst.go.jp/article/hansen1996/65/3/65_3_155/_article/-char/ja |
| Volume | 65 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| ispartofPNX | 日本ハンセン病学会雑誌, 1996/11/30, Vol.65(3), pp.155-165 |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV29ixQxFB_Os7GRExU_TrnCV8muM5PJVyWZcZZDURDu4LphPjLIFqfIXmPlgiKoYGFxhcIVFoKFgpXgn7Owev-FLx-7O3tYeGoTXjIvmZe8TPJ7meQlCK6Fcc1x4jeuECs0UCiPe1VEGuzLNZpEiP9b67fg7j22uZ3c3qE7Kyeud3Yt7Y2qfv3kt-dK_karmIZ6Nadkj6HZeaGYgDTqF0PUMIZ_pGPIGQgFkkMuQVBIBeQCxABEZh8lIAeGwFASyLnhROM_J4gfQQ1mhPKEzEw5MgVFTK40hjS15YSg-FFmlXtCpF2Aa1_HQVFLZKAyy0aMVI5IiSVc4fMUJxvmoqBugWKQJ5BmIJUXSUamavh2MV_WNbyCgRKGQGFVZPrLkuQSWyNfLGzYvdDeoaLviv9d3s4oT5K4R5i7K6avXZoQCU5IbrvobGpw11j4T4B0xvnI-Rb2kCFyfEdnIxraq6UelOYvQZ_R_jzXkoNv330Kx2daomC0IC7ALMWMwZzDK4ZoDJyMObd7Eu7c72JpHocdWx6BIZr7ncFYmkPVi8GXc-OIaBGXBqkuHBkhMMW4t8UdrLHu5uwChm8-57PWVPPGUiURzQ3Rtpnti7RQbWstOO1trA3lKnQmWBmWZ4Pe9OX-4fNvP9-8nj47mB68_bH_YjL-Mhl_mozfH777MP36ffr0o41-noxfnQu2B_lWttnzd4X0hohYS5zUpZa8YnWrqzoiOpRNQ8NWtqxtecnjRDYRbRoeloIgKKvMXaVx2CZxW8ZVExNyPljdfbirLwQbUmqGbVlpynhCtaiSmhBt_r9rIhlNLgY3Xe2KR84hTHFcDV765xIuB6cWn8x6sDp6vKevIDoeVVdtr_gFf6-PZw |
| linkProvider | Colorado Alliance of Research Libraries |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=%E6%8A%97%E9%85%B8%E8%8F%8C%E6%84%9F%E6%9F%93%E7%97%87%E3%81%AF%E3%81%AA%E3%81%9C%E9%9B%A3%E6%B2%BB%E6%80%A7%E3%81%AA%E3%81%AE%E3%81%8B&rft.jtitle=%E6%97%A5%E6%9C%AC%E3%83%8F%E3%83%B3%E3%82%BB%E3%83%B3%E7%97%85%E5%AD%A6%E4%BC%9A%E9%9B%91%E8%AA%8C&rft.au=%E5%86%A8%E5%B2%A1%2C+%E6%B2%BB%E6%98%8E&rft.date=1996-11-30&rft.pub=%E6%97%A5%E6%9C%AC%E3%83%8F%E3%83%B3%E3%82%BB%E3%83%B3%E7%97%85%E5%AD%A6%E4%BC%9A&rft.issn=1342-3681&rft.eissn=1884-314X&rft.volume=65&rft.issue=3&rft.spage=155&rft.epage=165&rft_id=info:doi/10.5025%2Fhansen.65.155&rft.externalDocID=article_hansen1996_65_3_65_3_155_article_char_ja |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1342-3681&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1342-3681&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1342-3681&client=summon |