微粒子製剤設計とDDS 血中滞留性リポソームによる抗癌剤の処方設計における最適化
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| Published in | Drug Delivery System Vol. 15; no. 5; pp. 437 - 442 |
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| Main Authors | , , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
日本DDS学会
10.09.2000
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| Online Access | Get full text |
| ISSN | 0913-5006 1881-2732 |
| DOI | 10.2745/dds.15.437 |
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| Author | 原島, 秀吉 土井, 久子 土橋, 麻理 際田, 弘志 |
|---|---|
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| DOI | 10.2745/dds.15.437 |
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| Discipline | Pharmacy, Therapeutics, & Pharmacology |
| EISSN | 1881-2732 |
| EndPage | 442 |
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| References | 7) 土橋麻理, 原島秀吉, 際田弘志 : リポソーム封入ドキソルビシンの腹腔癌における抗腫瘍効果制御システムの構築. Drug Del Sys 14 : 109-113, 1999. 5) Tsuchihashi M, Harashima H, Kiwada H : Development of a PK/PD-simulation system of doxorubicin in long circulating liposomes in mice with peritoneal P 388. J Cont Rel 61 : 9-19, 1999. 6) Harashima H, Tsuchihashi M, Iida S, Doi H, Kiwada H : Pharmacokinetic/pharmacodynainic modeling of antitumor agents encapsulated into liposomes. Adv Drug Dei Rev 40 : 39-61, 1999. 3) Mayer LD, Tai LCL, Bally MB, Mitilenes GN, Ginsberg RS, Cullis PR : Characterization of liposomal. systems containing doxorubicin entrapped in response to pH gradients. Biochem Biophys Acta 1025 : 143-151, 1990. 2) Harashima H, Kiwada H : Liposomal targeting and drug delivery : Kinetic consideration. Adv Drug Del Rev 19 : 425-444, 1996. 1) Allen TM, Chonn A : Large unilamellar liposomes with low uptake into the reticuloendothelial system. FEDS Lett 223 : 42-46, 1987. 4) Harashima H, Iida S, Urakami Y, Tsuchihashi M, Kiwada H : Optimization of antitumor effect of liposomaly encapsulated doxorubicin based on simulations by pharmacokinetic/pharmacodynamic modeling. J Cent Rel 61 : 93-106, 1999. |
| References_xml | – reference: 1) Allen TM, Chonn A : Large unilamellar liposomes with low uptake into the reticuloendothelial system. FEDS Lett 223 : 42-46, 1987. – reference: 3) Mayer LD, Tai LCL, Bally MB, Mitilenes GN, Ginsberg RS, Cullis PR : Characterization of liposomal. systems containing doxorubicin entrapped in response to pH gradients. Biochem Biophys Acta 1025 : 143-151, 1990. – reference: 2) Harashima H, Kiwada H : Liposomal targeting and drug delivery : Kinetic consideration. Adv Drug Del Rev 19 : 425-444, 1996. – reference: 6) Harashima H, Tsuchihashi M, Iida S, Doi H, Kiwada H : Pharmacokinetic/pharmacodynainic modeling of antitumor agents encapsulated into liposomes. Adv Drug Dei Rev 40 : 39-61, 1999. – reference: 7) 土橋麻理, 原島秀吉, 際田弘志 : リポソーム封入ドキソルビシンの腹腔癌における抗腫瘍効果制御システムの構築. Drug Del Sys 14 : 109-113, 1999. – reference: 4) Harashima H, Iida S, Urakami Y, Tsuchihashi M, Kiwada H : Optimization of antitumor effect of liposomaly encapsulated doxorubicin based on simulations by pharmacokinetic/pharmacodynamic modeling. J Cent Rel 61 : 93-106, 1999. – reference: 5) Tsuchihashi M, Harashima H, Kiwada H : Development of a PK/PD-simulation system of doxorubicin in long circulating liposomes in mice with peritoneal P 388. J Cont Rel 61 : 9-19, 1999. |
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| Subtitle | 血中滞留性リポソームによる抗癌剤の処方設計における最適化 |
| Title | 微粒子製剤設計とDDS |
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