MoMI-G: Modular Multi-scale Integrated Genome Graph Browser

Genome graph is an emerging approach for representing structural variants on genomes with branches. For example, representing structural variants of cancer genomes as a genome graph is more natural than representing such genomes as differences from the reference genome. However, there is currently n...

Full description

Saved in:
Bibliographic Details
Published inbioRxiv
Main Authors Yokoyama, Toshiyuki T, Sakamoto, Yoshitaka, Seki, Masahide, Suzuki, Yutaka, Kasahara, Masahiro
Format Paper
LanguageEnglish
Published Cold Spring Harbor Cold Spring Harbor Laboratory Press 11.03.2019
Subjects
Alleles
Cell lines
Genomes
Online AccessGet full text

Cover

Abstract Genome graph is an emerging approach for representing structural variants on genomes with branches. For example, representing structural variants of cancer genomes as a genome graph is more natural than representing such genomes as differences from the reference genome. However, there is currently no visualization method for large genome graphs, such as human cancer genomes. To this end, we developed MOdular Multi-scale Integrated Genome graph browser, MoMI-G, a web-based genome graph browser that can visualize genome graphs with structural variants and supporting evidences such as read alignments, read depth, and annotations.
AbstractList Genome graph is an emerging approach for representing structural variants on genomes with branches. For example, representing structural variants of cancer genomes as a genome graph is more natural than representing such genomes as differences from the reference genome. However, there is currently no visualization method for large genome graphs, such as human cancer genomes. To this end, we developed MOdular Multi-scale Integrated Genome graph browser, MoMI-G, a web-based genome graph browser that can visualize genome graphs with structural variants and supporting evidences such as read alignments, read depth, and annotations.
Author Suzuki, Yutaka
Kasahara, Masahiro
Seki, Masahide
Yokoyama, Toshiyuki T
Sakamoto, Yoshitaka
Author_xml – sequence: 1
  givenname: Toshiyuki
  surname: Yokoyama
  middlename: T
  fullname: Yokoyama, Toshiyuki T
– sequence: 2
  givenname: Yoshitaka
  surname: Sakamoto
  fullname: Sakamoto, Yoshitaka
– sequence: 3
  givenname: Masahide
  surname: Seki
  fullname: Seki, Masahide
– sequence: 4
  givenname: Yutaka
  surname: Suzuki
  fullname: Suzuki, Yutaka
– sequence: 5
  givenname: Masahiro
  surname: Kasahara
  fullname: Kasahara, Masahiro
BookMark eNotzbFOwzAUQFEPMECBb7DEbHi2YyeGCSoIkRqxtHP1HD8DVbCLk4jfBwmmu517zk5STsTYlYQbKUHemgqkgjN23-e-E-0d73NYRiy8X8b5Q0wDjsS7NNNbwZkCbynlT-JtweM7fyz5e6JywU4jjhNd_nfFds9P2_WL2Ly23fphIw5SWRDWVmTBa6XQx8HoxvjBONIRlQu-cRFNA-iRAuhQ1U420tlABmysK2ONXrHrP_dY8tdC07w_5KWk3-VeydqCs652-geZJkEH
ContentType Paper
Copyright 2019. This article is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (“the License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Copyright_xml – notice: 2019. This article is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (“the License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
DBID 8FE
8FH
AAFGM
AAMXL
ABOIG
ABUWG
ADZZV
AFKRA
AFLLJ
AFOLM
AGAJT
AQTIP
AZQEC
BBNVY
BENPR
BHPHI
CCPQU
DWQXO
GNUQQ
HCIFZ
LK8
M7P
PIMPY
PQCXX
PQEST
PQQKQ
PQUKI
PRINS
DOI 10.1101/540120
DatabaseName ProQuest SciTech Collection
ProQuest Natural Science Collection
ProQuest Central Korea - hybrid linking
Natural Science Collection - hybrid linking
Biological Science Collection - hybrid linking
ProQuest Central (Alumni)
ProQuest Central (Alumni) - hybrid linking
ProQuest Central UK/Ireland
SciTech Premium Collection - hybrid linking
ProQuest Central Student - hybrid linking
ProQuest Central Essentials - hybrid linking
ProQuest Women's & Gender Studies - hybrid linking
ProQuest Central Essentials
Biological Science Collection
ProQuest Central
ProQuest Natural Science Collection
ProQuest One Community College
ProQuest Central Korea
ProQuest Central Student
SciTech Premium Collection
ProQuest Biological Science Collection
Biological Science Database
Publicly Available Content Database
ProQuest Central - hybrid linking
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest Central China
DatabaseTitle Publicly Available Content Database
ProQuest Central Student
ProQuest Biological Science Collection
ProQuest Central Essentials
ProQuest One Academic Eastern Edition
ProQuest Central (Alumni Edition)
SciTech Premium Collection
ProQuest One Community College
ProQuest Natural Science Collection
Biological Science Database
ProQuest SciTech Collection
ProQuest Central China
ProQuest Central
ProQuest One Academic UKI Edition
Natural Science Collection
ProQuest Central Korea
Biological Science Collection
ProQuest One Academic
DatabaseTitleList Publicly Available Content Database
Database_xml – sequence: 1
  dbid: BENPR
  name: ProQuest Central
  url: https://www.proquest.com/central
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Genre Working Paper/Pre-Print
GroupedDBID 8FE
8FH
ABUWG
AFKRA
AZQEC
BBNVY
BENPR
BHPHI
CCPQU
DWQXO
GNUQQ
HCIFZ
LK8
M7P
PIMPY
PQEST
PQQKQ
PQUKI
PRINS
ID FETCH-LOGICAL-j1260-664e60b322abfc5385bc59e3fa29db89fa580abaed03d47918196de506f745653
IEDL.DBID BENPR
IngestDate Thu Oct 10 16:24:30 EDT 2024
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed false
IsScholarly false
Language English
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-j1260-664e60b322abfc5385bc59e3fa29db89fa580abaed03d47918196de506f745653
OpenAccessLink https://www.proquest.com/docview/2176096979?pq-origsite=%requestingapplication%
PQID 2176096979
PQPubID 2050091
ParticipantIDs proquest_journals_2176096979
PublicationCentury 2000
PublicationDate 20190311
PublicationDateYYYYMMDD 2019-03-11
PublicationDate_xml – month: 03
  year: 2019
  text: 20190311
  day: 11
PublicationDecade 2010
PublicationPlace Cold Spring Harbor
PublicationPlace_xml – name: Cold Spring Harbor
PublicationTitle bioRxiv
PublicationYear 2019
Publisher Cold Spring Harbor Laboratory Press
Publisher_xml – name: Cold Spring Harbor Laboratory Press
Score 1.7305825
Snippet Genome graph is an emerging approach for representing structural variants on genomes with branches. For example, representing structural variants of cancer...
SourceID proquest
SourceType Aggregation Database
SubjectTerms Alleles
Cell lines
Genomes
Title MoMI-G: Modular Multi-scale Integrated Genome Graph Browser
URI https://www.proquest.com/docview/2176096979
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LSwMxEA7aXrwpKj6q5OA1NMnuZjd6EJS-hC1FLPRWkkz2ILhbu-3_d7KkeBC85JJTPubxzSMzhDxIyHUBAph1Mmepqyqm8WQmCcPaubRJN8C0nKvpMn1bZauYcGtjW-XBJnaGGhoXcuRDpM4K6bbO9fPmm4WtUaG6GldoHJO-FGko0_ZfRvPFe1wihOI2REYiJP9jaTv3MT4l_YXZ-O0ZOfL1OXkqm3LGJo-0bCA0gdLuEyxrES1PZ4fxDUAnvm6-PJ2EkdI0hMsoLRdkOR59vE5Z3GHAPgWGCkyp1CtuUW2MrRxal8y6TPukMlKDLXRlsoIbazzwBNJco8PVCnzGVZUHspVckl7d1P6KUFdIKJSGBANaxBEs6p7WwJWTKhM2vSaDwxvXURDb9S9sN_9f35IT5AI6tFcJMSC93Xbv79Df7ux9BPUHDueBYw
link.rule.ids 786,790,21416,27956,33777,43838
linkProvider ProQuest
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV07T8MwELagHWADAeJRwAOrVcdJnBgGJFBf0FQVaqVule1zBiSSvvj_nCNXDEgsXjz50_nuu_P5O0IeBGQqhwiYsSJjiS1LpnBlOvZi7VyYuBEwLSZyOE_eFukiFNy2oa1y7xMbRw219TXyLlJniXRbZep5tWZ-apR_XQ0jNA5J20tu5i3SfulNph9hiBCaWxcZSST4H0_bhI_-CWlP9cptTsmBq87IU1EXIzZ4pEUNvgmUNp9g2RbRcnS0l28AOnBV_eXowEtKU58uo7Wck3m_N3sdsjDDgH1GmCowKRMnucFro01p0bukxqbKxaUWCkyuSp3mXBvtgMeQZAoDrpLgUi7LzJOt-IK0qrpyl4TaXEAuFcSY0CKOYPDuKQVcWiHTyCRXpLM_4zIY4nb5C9v1_9v35Gg4K8bL8WjyfkOOkRco32oVRR3S2m2-3S3G3p25CwD_AFAzhFk
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=MoMI-G%3A+Modular+Multi-scale+Integrated+Genome+Graph+Browser&rft.jtitle=bioRxiv&rft.au=Yokoyama%2C+Toshiyuki+T&rft.au=Sakamoto%2C+Yoshitaka&rft.au=Seki%2C+Masahide&rft.au=Suzuki%2C+Yutaka&rft.date=2019-03-11&rft.pub=Cold+Spring+Harbor+Laboratory+Press&rft_id=info:doi/10.1101%2F540120