Clinical Investigation of Pharmaceutical Instructions for the Use of a Metered Dose Inhaler by Inpatients with Bronchial Asthma
In order to investigate the efficacy of pharmaceutical instruction including the instructions for use of a metered dose inhaler by inpatients with chronic bronchial asthma, intervals of hospital visits, therapeutic scores in the prescription and in the consulting room were assessed in twelve patient...
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| Published in | Japanese Journal of Hospital Pharmacy Vol. 24; no. 1; pp. 63 - 70 |
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| Main Authors | , , , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
Japanese Society of Pharmaceutical Health Care and Sciences
1998
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| Subjects | |
| Online Access | Get full text |
| ISSN | 0389-9098 2185-9477 |
| DOI | 10.5649/jjphcs1975.24.63 |
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| Abstract | In order to investigate the efficacy of pharmaceutical instruction including the instructions for use of a metered dose inhaler by inpatients with chronic bronchial asthma, intervals of hospital visits, therapeutic scores in the prescription and in the consulting room were assessed in twelve patients who were treated at Yamagata University Hospital. No patients who re-entered the hospital were recognized after their discharge from the hospital (12.8-30.4 months). The mean times of exacerbation needed for the intra-venous injection of steroids and/or aminophylline during the one year period before and after the last hospitalization in which pharmaceutical instructions were given, were 2.8 and 1.6, respectively. One of the 12 patients received the injections for treatment of asthma only one time during the one year period. In seven patients who received oral corticosteroids at discharge, three patients were able to discontinue and two patients were able to decrease their dosage. Although it was difficult to obtain any specific contribution ratio on their clinical efficacy, the pharmaceutical service including usage instruction of the metered dose inhaler by pharmacists to the patients with bronchial asthma was found to be useful especially for patients who had been repeatedly hospitalized. |
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| AbstractList | In order to investigate the efficacy of pharmaceutical instruction including the instructions for use of a metered dose inhaler by inpatients with chronic bronchial asthma, intervals of hospital visits, therapeutic scores in the prescription and in the consulting room were assessed in twelve patients who were treated at Yamagata University Hospital. No patients who re-entered the hospital were recognized after their discharge from the hospital (12.8-30.4 months). The mean times of exacerbation needed for the intra-venous injection of steroids and/or aminophylline during the one year period before and after the last hospitalization in which pharmaceutical instructions were given, were 2.8 and 1.6, respectively. One of the 12 patients received the injections for treatment of asthma only one time during the one year period. In seven patients who received oral corticosteroids at discharge, three patients were able to discontinue and two patients were able to decrease their dosage. Although it was difficult to obtain any specific contribution ratio on their clinical efficacy, the pharmaceutical service including usage instruction of the metered dose inhaler by pharmacists to the patients with bronchial asthma was found to be useful especially for patients who had been repeatedly hospitalized. |
| Author | TOMOIKE, HITONOBU NAKAGAWA, YOSHITO OJIMA, FUMIYOSHI NAKAMURA, HIDENORI SHOJI, TOHRU |
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| References | 10) 中島明雄,“気管支喘息診療ガイド-ICRガイドラインをふまえて-”, 5気管支喘息の治療, III慢性喘息患者の管理, B日常生活上の管理, 宮城征四郎編, 中外医学社, 東京, 1995, pp.146-149. 17) 木野稔也, 佐竹範夫, 安場広高, 川口英人, 楠目馨, 大島駿作, 浅本仁, 故倉恵, 大山口渥, 中山昌彦, 中村昇, 辻重行, 中橋弥生, 原洋, 中村泰三, 杉本幾久雄, 成人気管支喘息患者における定量噴霧式吸入器 (MDDの吸入様式の調査とprocaterol吸入に対する吸入方法指導前後の気管支拡張効果の検討. 呼吸, 8, 1213-1221 (1989). 本昭正編集, 高久史麿監修, 南江堂, 東京, 1991, pp.191-198. 18) 山本雅人, 山本健市, 高木健三, 小倉庸蔵, 長谷川高明, 鍋島俊隆, 気管支喘息患者における定量噴霧吸入器 (MDI) の使用上の問題点に関する患者指導の有用性. 呼吸, 14,189-194 (1995). 13) 渡邊好明, 田中斉, 谷澤誠, 大型スペーサーを用いたプロピオン酸ベクロメタゾン吸入療法導入前後の気管支喘息患者救急受診状況の検討, アレルギー, 44,529-533 (1995). 14) 牧野荘平監修:“成人喘息の診断と治療, 日本アレルギー学会, アレルギー疾患治療ガイドライン, 95年改訂版” 第4章喘息の長期管理における薬物療法プラン. ライフサイエンス・メディカ社, 1995, 東京, pp.28-37. 15) 中島明雄,“気管支喘息診療ガイド-ICRガイドラインをふまえて-”, 5気管支喘息の治療, 1喘息の薬物療法, F喘息治療における吸入量法の位置付け.宮城征四郎編, 中外医学社, 東京, 1995, pp.102-110. 3) 鈴木亨, 伸川義人, POS導入による服薬指導の一考察, 薬局, 46, 1909-1917 (1995). 6) F. E. Hargreave, J. Dolovich and M. T. Newhouse,-Editors, The assessment and treatment of asthma, A conference report, J. Allergy Clin. Immunol., 85, 1098-1111 (1990). 4) 鈴木亨, 仲川義人, 適切な服薬指導のためのPOS利用, 日本病院薬剤師会雑誌, 31,997-1000 (1995). 7) K. Tsukioka, S. Makino, T. Miyamoto, H. Mikawa, K. Ito, H. Tomioka, T. Takahashi, M. Adachi, M. Baba and K. Nishikawa, Questionnaire survey on asthma management of Japanese allergists I. Diagnosis, patient education and management, Allergology Int., 45,113-116 (1996). 5) 吉田慎一, 在宅癌性疼痛緩和療法への支援と服薬指導, Pharmacy Today, 8, 17-21 (1995). 8) 谷元晋一,“COMMON DISEASESERIES 8気管支喘息”, 5治療と患者指導, F生活指導, 宮 1) 早川達, 田村広志, 小笹義人, 大浦勝司, 林三樹夫, POSによる薬剤管理指導業務-薬剤師による初回面談時情報の重要性-, 日本病院薬剤師会雑誌, 32,301-305 (1996). 12) 福岡淳一, 慢性喘息発作に対するステロイド剤の効果, ピークフロー値の日内変動パターンに着目して, 日胸疾会誌, 32,731-738 (1994). 9) 牧野荘平監修:“成人喘息の診断と治療, 日本アレルギー学会, アレルギー疾患治療ガイドライン, 95年改訂版” 第1章喘息の定義, 診断, 病型, 重症度分類. ライフサイエンス・メディカ社, 1995, 東京. pp16-22. 16) M. T. Newhouse, M. B. Dolovich and P. Eng, Control of asthma by aerosols, N. Engl. J. Med., 315,870-874 (1986). 11) 小嶋文良, 中村秀範, 友池仁暢, 東海林徹, 仲川義人, 定量噴霧吸入剤 (MDI) 吸入指導に関する問題点と臨床効果に関する検討, 喘息, 10, 95-102 (1997). 2) 尾形浩, 高橋智子, 江戸清人, 薬剤管理指導業務の客観的評価 [I]-薬剤師による処方への参画に関する調査-, 日本病院薬剤師会雑誌, 32, 1085-1088 (1996). |
| References_xml | – reference: 17) 木野稔也, 佐竹範夫, 安場広高, 川口英人, 楠目馨, 大島駿作, 浅本仁, 故倉恵, 大山口渥, 中山昌彦, 中村昇, 辻重行, 中橋弥生, 原洋, 中村泰三, 杉本幾久雄, 成人気管支喘息患者における定量噴霧式吸入器 (MDDの吸入様式の調査とprocaterol吸入に対する吸入方法指導前後の気管支拡張効果の検討. 呼吸, 8, 1213-1221 (1989). – reference: 15) 中島明雄,“気管支喘息診療ガイド-ICRガイドラインをふまえて-”, 5気管支喘息の治療, 1喘息の薬物療法, F喘息治療における吸入量法の位置付け.宮城征四郎編, 中外医学社, 東京, 1995, pp.102-110. – reference: 6) F. E. Hargreave, J. Dolovich and M. T. Newhouse,-Editors, The assessment and treatment of asthma, A conference report, J. Allergy Clin. Immunol., 85, 1098-1111 (1990). – reference: 4) 鈴木亨, 仲川義人, 適切な服薬指導のためのPOS利用, 日本病院薬剤師会雑誌, 31,997-1000 (1995). – reference: 1) 早川達, 田村広志, 小笹義人, 大浦勝司, 林三樹夫, POSによる薬剤管理指導業務-薬剤師による初回面談時情報の重要性-, 日本病院薬剤師会雑誌, 32,301-305 (1996). – reference: 5) 吉田慎一, 在宅癌性疼痛緩和療法への支援と服薬指導, Pharmacy Today, 8, 17-21 (1995). – reference: 2) 尾形浩, 高橋智子, 江戸清人, 薬剤管理指導業務の客観的評価 [I]-薬剤師による処方への参画に関する調査-, 日本病院薬剤師会雑誌, 32, 1085-1088 (1996). – reference: 本昭正編集, 高久史麿監修, 南江堂, 東京, 1991, pp.191-198. – reference: 12) 福岡淳一, 慢性喘息発作に対するステロイド剤の効果, ピークフロー値の日内変動パターンに着目して, 日胸疾会誌, 32,731-738 (1994). – reference: 7) K. Tsukioka, S. Makino, T. Miyamoto, H. Mikawa, K. Ito, H. Tomioka, T. Takahashi, M. Adachi, M. Baba and K. Nishikawa, Questionnaire survey on asthma management of Japanese allergists I. Diagnosis, patient education and management, Allergology Int., 45,113-116 (1996). – reference: 16) M. T. Newhouse, M. B. Dolovich and P. Eng, Control of asthma by aerosols, N. Engl. J. Med., 315,870-874 (1986). – reference: 18) 山本雅人, 山本健市, 高木健三, 小倉庸蔵, 長谷川高明, 鍋島俊隆, 気管支喘息患者における定量噴霧吸入器 (MDI) の使用上の問題点に関する患者指導の有用性. 呼吸, 14,189-194 (1995). – reference: 13) 渡邊好明, 田中斉, 谷澤誠, 大型スペーサーを用いたプロピオン酸ベクロメタゾン吸入療法導入前後の気管支喘息患者救急受診状況の検討, アレルギー, 44,529-533 (1995). – reference: 14) 牧野荘平監修:“成人喘息の診断と治療, 日本アレルギー学会, アレルギー疾患治療ガイドライン, 95年改訂版” 第4章喘息の長期管理における薬物療法プラン. ライフサイエンス・メディカ社, 1995, 東京, pp.28-37. – reference: 3) 鈴木亨, 伸川義人, POS導入による服薬指導の一考察, 薬局, 46, 1909-1917 (1995). – reference: 8) 谷元晋一,“COMMON DISEASESERIES 8気管支喘息”, 5治療と患者指導, F生活指導, 宮 – reference: 10) 中島明雄,“気管支喘息診療ガイド-ICRガイドラインをふまえて-”, 5気管支喘息の治療, III慢性喘息患者の管理, B日常生活上の管理, 宮城征四郎編, 中外医学社, 東京, 1995, pp.146-149. – reference: 11) 小嶋文良, 中村秀範, 友池仁暢, 東海林徹, 仲川義人, 定量噴霧吸入剤 (MDI) 吸入指導に関する問題点と臨床効果に関する検討, 喘息, 10, 95-102 (1997). – reference: 9) 牧野荘平監修:“成人喘息の診断と治療, 日本アレルギー学会, アレルギー疾患治療ガイドライン, 95年改訂版” 第1章喘息の定義, 診断, 病型, 重症度分類. ライフサイエンス・メディカ社, 1995, 東京. pp16-22. |
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| Title | Clinical Investigation of Pharmaceutical Instructions for the Use of a Metered Dose Inhaler by Inpatients with Bronchial Asthma |
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