Comparison of Clinical Features in Surgical Treatment of Lung Cancer over Two 10-Year Periods in Shinshu University Hospital

Lung cancer is one of the most common fatal cancers. We retrospectively evaluated 949 resected cases of lung cancer from January 1985 to December 2004 by comparative analysis of the first (1985-1994) and second 10-year period (1995-2004) with reference to patient age, gender, chief complaint, histol...

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Published inTHE SHINSHU MEDICAL JOURNAL Vol. 56; no. 1; pp. 17 - 28
Main Authors KONDO, Ryoichi, SAKAIZAWA, Takao, KATO, Kyoko, TOMINAGA, Yoshiaki, EGUCHI, Takashi, KOBAYASHI, Nobutaka, HYOGOTANI, Akira, SAITO, Gaku, USHIYAMA, Toshiki, HAMANAKA, Kazutoshi, TOISHI, Masayuki, HASIZUME, Masahiro, SHIINA, Takayuki, MAKIUCHI, Akiko, KURAI, Makoto, TAKASUNA, Keiichiro, NUMANAMI, Hiroki, MIYAZAWA, Masahisa, YOSHIDA, Kazuo, YAMANDA, Takeshi, HANIUDA, Masayuki, AMANO, Jun
Format Journal Article
LanguageEnglish
Japanese
Published The Shinshu Medical Society 2008
Subjects
CT screening
lung cancer
operative procedure
prognosis
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Abstract Lung cancer is one of the most common fatal cancers. We retrospectively evaluated 949 resected cases of lung cancer from January 1985 to December 2004 by comparative analysis of the first (1985-1994) and second 10-year period (1995-2004) with reference to patient age, gender, chief complaint, histological type, tumor differentiation, tumor size, operative method, pathological stage, and survival rate. Surgical treatment for patients older than 75 years of age doubled in the second 10-year period. CT health screenings indicating lung cancer increased. The percentage of well-differentiated adenocarcinoma increased in both males and females. Cases of tumors less than 20mm, especially those less than 10mm, increased in the second 10-year period. The ratio of pneumonectomy decreased, and limited resection including partial resection and segmentectomy increased. The number of cases in pathological stage IA increased. The 5-year survival rates in stages IA, III A, IV, and overall in the second period were statistically higher than in the first period. An age of 70 years of more, being male, first medical contact other than CT health screening, CEA elevation, histological type other than well-differentiated adenocarcinoma, tumor size, lymph node metastasis, and pneumonectomy were all considered factors impacting survival in resected cases of lung cancer.
AbstractList Lung cancer is one of the most common fatal cancers. We retrospectively evaluated 949 resected cases of lung cancer from January 1985 to December 2004 by comparative analysis of the first (1985-1994) and second 10-year period (1995-2004) with reference to patient age, gender, chief complaint, histological type, tumor differentiation, tumor size, operative method, pathological stage, and survival rate. Surgical treatment for patients older than 75 years of age doubled in the second 10-year period. CT health screenings indicating lung cancer increased. The percentage of well-differentiated adenocarcinoma increased in both males and females. Cases of tumors less than 20mm, especially those less than 10mm, increased in the second 10-year period. The ratio of pneumonectomy decreased, and limited resection including partial resection and segmentectomy increased. The number of cases in pathological stage IA increased. The 5-year survival rates in stages IA, III A, IV, and overall in the second period were statistically higher than in the first period. An age of 70 years of more, being male, first medical contact other than CT health screening, CEA elevation, histological type other than well-differentiated adenocarcinoma, tumor size, lymph node metastasis, and pneumonectomy were all considered factors impacting survival in resected cases of lung cancer.
Author AMANO, Jun
TOMINAGA, Yoshiaki
MAKIUCHI, Akiko
KURAI, Makoto
USHIYAMA, Toshiki
HASIZUME, Masahiro
HAMANAKA, Kazutoshi
MIYAZAWA, Masahisa
HANIUDA, Masayuki
YOSHIDA, Kazuo
YAMANDA, Takeshi
SAITO, Gaku
TAKASUNA, Keiichiro
KOBAYASHI, Nobutaka
HYOGOTANI, Akira
KONDO, Ryoichi
EGUCHI, Takashi
SHIINA, Takayuki
TOISHI, Masayuki
NUMANAMI, Hiroki
KATO, Kyoko
SAKAIZAWA, Takao
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  organization: Department of Surgery, Shinshu University School of Medicine
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  fullname: MAKIUCHI, Akiko
  organization: Department of Surgery, Shinshu University School of Medicine
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  fullname: KURAI, Makoto
  organization: Department of Surgery, Shinshu University School of Medicine
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  fullname: TAKASUNA, Keiichiro
  organization: Department of Surgery, Shinshu University School of Medicine
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  fullname: NUMANAMI, Hiroki
  organization: Department of Surgery, Shinshu University School of Medicine
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  fullname: MIYAZAWA, Masahisa
  organization: Department of Surgery, Shinshu University School of Medicine
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  fullname: YOSHIDA, Kazuo
  organization: Department of Surgery, Shinshu University School of Medicine
– sequence: 20
  fullname: YAMANDA, Takeshi
  organization: Department of Surgery, Shinshu University School of Medicine
– sequence: 21
  fullname: HANIUDA, Masayuki
  organization: Department of Surgery, Shinshu University School of Medicine
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  fullname: AMANO, Jun
  organization: Department of Surgery, Shinshu University School of Medicine
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SubjectTerms CT screening
lung cancer
operative procedure
prognosis
Title Comparison of Clinical Features in Surgical Treatment of Lung Cancer over Two 10-Year Periods in Shinshu University Hospital
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