Successful treatment with venetoclax and azacitidine for extramedullary relapse of acute myeloid leukemia after cord blood transplantation

• Published in: Rinshō ketsueki Vol. 65; no. 10; p. 1259
• Main Authors: Takeda, Takaaki, Suzuki, Taisei, Enaka, Makiko, Izumi, Akihiko, Tachibana, Takayoshi, Tanaka, Masatsugu, Fujimaki, Katsumichi, Nakajima, Hideaki
• Format: Journal Article
• Language: Japanese
• Published: Japan 2024
• Subjects: Adult; Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Azacitidine - administration & dosage; Azacitidine - therapeutic use; Bridged Bicyclo Compounds, Heterocyclic - administration & dosage; Bridged Bicyclo Compounds, Heterocyclic - therapeutic use; Cord Blood Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute - drug therapy; Leukemia, Myeloid, Acute - pathology; Leukemia, Myeloid, Acute - therapy; Male; Recurrence; Sulfonamides - administration & dosage; Sulfonamides - therapeutic use; Treatment Outcome; Azacitidine; Venetoclax; Extramedullary relapse

A 33-year-old man was diagnosed with acute myeloid leukemia (AML). He was treated with daunorubicin and cytarabine and achieved complete remission. He underwent consolidation therapy with three cycles of venetoclax and azacitidine (VEN+AZA). He received cord blood transplantation following a reduced...