Importance of gene mutation analysis as prognostic factor of acute myeloid leukemia

• Published in: Rinshō ketsueki Vol. 61; no. 9; p. 1160
• Main Author: Yamaguchi, Hiroki
• Format: Journal Article
• Language: Japanese
• Published: Japan 2020
• Subjects: Europe; fms-Like Tyrosine Kinase 3 - genetics; Humans; Japan; Leukemia, Myeloid, Acute - diagnosis; Leukemia, Myeloid, Acute - genetics; Leukemia, Myeloid, Acute - therapy; Mutation; Prognosis; Europe; Japan; Molecular diagnosis; Molecular targeted drug; Gene mutation; Acute myeloid leukemia

In acute myeloid leukemia (AML), a number of chromosomal abnormalities and gene mutations associated with onset and recurrence were discovered by the recent progress of genome analysis technology. The founding did not only have clinical application as prognostic factors and minimal residual disease...