Four cases of granulomatous mastitis

We report 4 cases of granulomatous mastitis, one of which showed Corynebacterium Kroppenstedtii infection. Case 1 : A 38-year-old woman presented with a mass measuring 3.8×3.0 cm in the upper outer quadrant of her left breast. The histological diagnosis was granulomatous mastitis. Treatment with ant...

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Published inNihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) Vol. 73; no. 6; pp. 1331 - 1336
Main Authors MIURA, Murato, KINOSHITA, Takahumi, MATSUYAMA, Kazuo, GOTO, Masakazu, TOYOTA, Tsuyoshi, MORIMOTO, Tadaoki
Format Journal Article
LanguageJapanese
Published Japan Surgical Association 2012
Subjects
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ISSN1345-2843
1882-5133
DOI10.3919/jjsa.73.1331

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Abstract We report 4 cases of granulomatous mastitis, one of which showed Corynebacterium Kroppenstedtii infection. Case 1 : A 38-year-old woman presented with a mass measuring 3.8×3.0 cm in the upper outer quadrant of her left breast. The histological diagnosis was granulomatous mastitis. Treatment with antibiotics and steroids was not effective. Finally, surgical abscess drainage was performed. Case 2 : A 36-year-old woman presented with mass measuring 3.0×2.5 cm in the upper half of her left breast. A diagnosis of granulomatous mastitis was made, and she had no complaints during the follow-up period. Case 3 : A 39-year-old woman presented with a mass measuring 4.2×4.0 cm in the inner half of her right breast. The histological diagnosis was granulomatous mastitis. Treatment with antibiotics was not effective. Finally, surgical abscess drainage was performed. Case 4 : A 34-year-old woman presented with a mass measuring 2.0×2.0 cm in the upper inner quadrant of her right breast. Cytologic examination showed no malignant cells, and the histological diagnosis was granulomatous mastitis. Polymerase chain reaction (PCR) analysis revealed kroppenstedtii infection, and the patient was successfully treated with minomycin.
AbstractList We report 4 cases of granulomatous mastitis, one of which showed Corynebacterium Kroppenstedtii infection. Case 1 : A 38-year-old woman presented with a mass measuring 3.8×3.0 cm in the upper outer quadrant of her left breast. The histological diagnosis was granulomatous mastitis. Treatment with antibiotics and steroids was not effective. Finally, surgical abscess drainage was performed. Case 2 : A 36-year-old woman presented with mass measuring 3.0×2.5 cm in the upper half of her left breast. A diagnosis of granulomatous mastitis was made, and she had no complaints during the follow-up period. Case 3 : A 39-year-old woman presented with a mass measuring 4.2×4.0 cm in the inner half of her right breast. The histological diagnosis was granulomatous mastitis. Treatment with antibiotics was not effective. Finally, surgical abscess drainage was performed. Case 4 : A 34-year-old woman presented with a mass measuring 2.0×2.0 cm in the upper inner quadrant of her right breast. Cytologic examination showed no malignant cells, and the histological diagnosis was granulomatous mastitis. Polymerase chain reaction (PCR) analysis revealed kroppenstedtii infection, and the patient was successfully treated with minomycin.
Author KINOSHITA, Takahumi
GOTO, Masakazu
MORIMOTO, Tadaoki
MIURA, Murato
TOYOTA, Tsuyoshi
MATSUYAMA, Kazuo
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  fullname: MATSUYAMA, Kazuo
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  fullname: MORIMOTO, Tadaoki
  organization: Department of Surgery, Shikoku Central Hospital of the Mutual Aid Association of Public School Teachers
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References 1) Kessler E, Wolloch Y : Granulomatous mastitis : A lesion clinically simulating carcinoma. Am J Clin Pathol 1972 ; 58 : 642-646
11) 大楠清文:Corynebacterium kroppenstedtii. Med Technol 2011;39:1072-1078
4) 重松英朗,中村吉昭,古閑知奈美他:Corynebacterium kroppenstedtii感染にて発症した肉芽腫性乳腺炎の1例.日臨外会誌 2008;69:3069-3073
12) 一本杉聡,崔 哲洵,松木康真他:肉芽腫性乳腺炎の8例.日臨外会誌 2011;72:2776-2781
6) Carmalt HL, Ramsey-Stewart G : Granulomatous mastitis. Med J Aust 1981 ; 1 : 356-359
8) 加藤久美子,神尾麻紀子,野木裕子他:肉芽腫性乳腺炎の3例―ステロイド治療の検討―.乳癌の臨 2010;25:593-598
10) Bartels CC, van Geel AN, van de Merwe JP : Granulomatous mastitis : a rare cause of breast swelling. Ned Tijdschr Geneeskd 2008 ; 152 : 294-295
9) Mathelin C, Riegel P, Chenard MP, et al : Granulomatous mastitis and corynebacteria : clinical and pathologic correlations. Breast J 2005 ; 11 : 357
5) Donn W, Rebbeck P, Wilson CK, et al : Idiopathic granulomatous mastitis : A report of three cases and review of the literature. Arch Pathol Lab Med 1994 ; 118 : 822-825
3) Bercot B, Kannengiesser C, Oudin C, et al : First description of NOD2 variant associated with defective neutrophil responses in a woman with granulomatous mastitis related to corynebacteria. J Clin Microbiol 2009 ; 47 : 3034-3037
7) DeHertogh DA, Rossof AH, Harris AA, et al : Prednisone management of granulomatous mastitis. N Engl J Med 1980 ; 303 : 799-800
2) Paviour S, Musaad S, Roberts S, et al : Corynebacterium species isolated from patients with mastitis. Clin Infect Dis 2002 ; 35 : 1434-1440
References_xml – reference: 3) Bercot B, Kannengiesser C, Oudin C, et al : First description of NOD2 variant associated with defective neutrophil responses in a woman with granulomatous mastitis related to corynebacteria. J Clin Microbiol 2009 ; 47 : 3034-3037
– reference: 12) 一本杉聡,崔 哲洵,松木康真他:肉芽腫性乳腺炎の8例.日臨外会誌 2011;72:2776-2781
– reference: 1) Kessler E, Wolloch Y : Granulomatous mastitis : A lesion clinically simulating carcinoma. Am J Clin Pathol 1972 ; 58 : 642-646
– reference: 4) 重松英朗,中村吉昭,古閑知奈美他:Corynebacterium kroppenstedtii感染にて発症した肉芽腫性乳腺炎の1例.日臨外会誌 2008;69:3069-3073
– reference: 10) Bartels CC, van Geel AN, van de Merwe JP : Granulomatous mastitis : a rare cause of breast swelling. Ned Tijdschr Geneeskd 2008 ; 152 : 294-295
– reference: 5) Donn W, Rebbeck P, Wilson CK, et al : Idiopathic granulomatous mastitis : A report of three cases and review of the literature. Arch Pathol Lab Med 1994 ; 118 : 822-825
– reference: 6) Carmalt HL, Ramsey-Stewart G : Granulomatous mastitis. Med J Aust 1981 ; 1 : 356-359
– reference: 7) DeHertogh DA, Rossof AH, Harris AA, et al : Prednisone management of granulomatous mastitis. N Engl J Med 1980 ; 303 : 799-800
– reference: 9) Mathelin C, Riegel P, Chenard MP, et al : Granulomatous mastitis and corynebacteria : clinical and pathologic correlations. Breast J 2005 ; 11 : 357
– reference: 2) Paviour S, Musaad S, Roberts S, et al : Corynebacterium species isolated from patients with mastitis. Clin Infect Dis 2002 ; 35 : 1434-1440
– reference: 8) 加藤久美子,神尾麻紀子,野木裕子他:肉芽腫性乳腺炎の3例―ステロイド治療の検討―.乳癌の臨 2010;25:593-598
– reference: 11) 大楠清文:Corynebacterium kroppenstedtii. Med Technol 2011;39:1072-1078
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Snippet We report 4 cases of granulomatous mastitis, one of which showed Corynebacterium Kroppenstedtii infection. Case 1 : A 38-year-old woman presented with a mass...
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SubjectTerms Corynebacterium Kroppenstedtii
granulomatous mastitis
steroid
Title Four cases of granulomatous mastitis
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