Four cases of granulomatous mastitis
We report 4 cases of granulomatous mastitis, one of which showed Corynebacterium Kroppenstedtii infection. Case 1 : A 38-year-old woman presented with a mass measuring 3.8×3.0 cm in the upper outer quadrant of her left breast. The histological diagnosis was granulomatous mastitis. Treatment with ant...
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Published in | Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) Vol. 73; no. 6; pp. 1331 - 1336 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | Japanese |
Published |
Japan Surgical Association
2012
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Subjects | |
Online Access | Get full text |
ISSN | 1345-2843 1882-5133 |
DOI | 10.3919/jjsa.73.1331 |
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Abstract | We report 4 cases of granulomatous mastitis, one of which showed Corynebacterium Kroppenstedtii infection. Case 1 : A 38-year-old woman presented with a mass measuring 3.8×3.0 cm in the upper outer quadrant of her left breast. The histological diagnosis was granulomatous mastitis. Treatment with antibiotics and steroids was not effective. Finally, surgical abscess drainage was performed. Case 2 : A 36-year-old woman presented with mass measuring 3.0×2.5 cm in the upper half of her left breast. A diagnosis of granulomatous mastitis was made, and she had no complaints during the follow-up period. Case 3 : A 39-year-old woman presented with a mass measuring 4.2×4.0 cm in the inner half of her right breast. The histological diagnosis was granulomatous mastitis. Treatment with antibiotics was not effective. Finally, surgical abscess drainage was performed. Case 4 : A 34-year-old woman presented with a mass measuring 2.0×2.0 cm in the upper inner quadrant of her right breast. Cytologic examination showed no malignant cells, and the histological diagnosis was granulomatous mastitis. Polymerase chain reaction (PCR) analysis revealed kroppenstedtii infection, and the patient was successfully treated with minomycin. |
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AbstractList | We report 4 cases of granulomatous mastitis, one of which showed Corynebacterium Kroppenstedtii infection. Case 1 : A 38-year-old woman presented with a mass measuring 3.8×3.0 cm in the upper outer quadrant of her left breast. The histological diagnosis was granulomatous mastitis. Treatment with antibiotics and steroids was not effective. Finally, surgical abscess drainage was performed. Case 2 : A 36-year-old woman presented with mass measuring 3.0×2.5 cm in the upper half of her left breast. A diagnosis of granulomatous mastitis was made, and she had no complaints during the follow-up period. Case 3 : A 39-year-old woman presented with a mass measuring 4.2×4.0 cm in the inner half of her right breast. The histological diagnosis was granulomatous mastitis. Treatment with antibiotics was not effective. Finally, surgical abscess drainage was performed. Case 4 : A 34-year-old woman presented with a mass measuring 2.0×2.0 cm in the upper inner quadrant of her right breast. Cytologic examination showed no malignant cells, and the histological diagnosis was granulomatous mastitis. Polymerase chain reaction (PCR) analysis revealed kroppenstedtii infection, and the patient was successfully treated with minomycin. |
Author | KINOSHITA, Takahumi GOTO, Masakazu MORIMOTO, Tadaoki MIURA, Murato TOYOTA, Tsuyoshi MATSUYAMA, Kazuo |
Author_xml | – sequence: 1 fullname: MIURA, Murato organization: Department of Surgery, Shikoku Central Hospital of the Mutual Aid Association of Public School Teachers – sequence: 1 fullname: KINOSHITA, Takahumi organization: Department of Surgery, Shikoku Central Hospital of the Mutual Aid Association of Public School Teachers – sequence: 1 fullname: MATSUYAMA, Kazuo organization: Department of Surgery, Shikoku Central Hospital of the Mutual Aid Association of Public School Teachers – sequence: 1 fullname: GOTO, Masakazu organization: Department of Surgery, Shikoku Central Hospital of the Mutual Aid Association of Public School Teachers – sequence: 1 fullname: TOYOTA, Tsuyoshi organization: Department of Surgery, Shikoku Central Hospital of the Mutual Aid Association of Public School Teachers – sequence: 1 fullname: MORIMOTO, Tadaoki organization: Department of Surgery, Shikoku Central Hospital of the Mutual Aid Association of Public School Teachers |
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References | 1) Kessler E, Wolloch Y : Granulomatous mastitis : A lesion clinically simulating carcinoma. Am J Clin Pathol 1972 ; 58 : 642-646 11) 大楠清文:Corynebacterium kroppenstedtii. Med Technol 2011;39:1072-1078 4) 重松英朗,中村吉昭,古閑知奈美他:Corynebacterium kroppenstedtii感染にて発症した肉芽腫性乳腺炎の1例.日臨外会誌 2008;69:3069-3073 12) 一本杉聡,崔 哲洵,松木康真他:肉芽腫性乳腺炎の8例.日臨外会誌 2011;72:2776-2781 6) Carmalt HL, Ramsey-Stewart G : Granulomatous mastitis. Med J Aust 1981 ; 1 : 356-359 8) 加藤久美子,神尾麻紀子,野木裕子他:肉芽腫性乳腺炎の3例―ステロイド治療の検討―.乳癌の臨 2010;25:593-598 10) Bartels CC, van Geel AN, van de Merwe JP : Granulomatous mastitis : a rare cause of breast swelling. Ned Tijdschr Geneeskd 2008 ; 152 : 294-295 9) Mathelin C, Riegel P, Chenard MP, et al : Granulomatous mastitis and corynebacteria : clinical and pathologic correlations. Breast J 2005 ; 11 : 357 5) Donn W, Rebbeck P, Wilson CK, et al : Idiopathic granulomatous mastitis : A report of three cases and review of the literature. Arch Pathol Lab Med 1994 ; 118 : 822-825 3) Bercot B, Kannengiesser C, Oudin C, et al : First description of NOD2 variant associated with defective neutrophil responses in a woman with granulomatous mastitis related to corynebacteria. J Clin Microbiol 2009 ; 47 : 3034-3037 7) DeHertogh DA, Rossof AH, Harris AA, et al : Prednisone management of granulomatous mastitis. N Engl J Med 1980 ; 303 : 799-800 2) Paviour S, Musaad S, Roberts S, et al : Corynebacterium species isolated from patients with mastitis. Clin Infect Dis 2002 ; 35 : 1434-1440 |
References_xml | – reference: 3) Bercot B, Kannengiesser C, Oudin C, et al : First description of NOD2 variant associated with defective neutrophil responses in a woman with granulomatous mastitis related to corynebacteria. J Clin Microbiol 2009 ; 47 : 3034-3037 – reference: 12) 一本杉聡,崔 哲洵,松木康真他:肉芽腫性乳腺炎の8例.日臨外会誌 2011;72:2776-2781 – reference: 1) Kessler E, Wolloch Y : Granulomatous mastitis : A lesion clinically simulating carcinoma. Am J Clin Pathol 1972 ; 58 : 642-646 – reference: 4) 重松英朗,中村吉昭,古閑知奈美他:Corynebacterium kroppenstedtii感染にて発症した肉芽腫性乳腺炎の1例.日臨外会誌 2008;69:3069-3073 – reference: 10) Bartels CC, van Geel AN, van de Merwe JP : Granulomatous mastitis : a rare cause of breast swelling. Ned Tijdschr Geneeskd 2008 ; 152 : 294-295 – reference: 5) Donn W, Rebbeck P, Wilson CK, et al : Idiopathic granulomatous mastitis : A report of three cases and review of the literature. Arch Pathol Lab Med 1994 ; 118 : 822-825 – reference: 6) Carmalt HL, Ramsey-Stewart G : Granulomatous mastitis. Med J Aust 1981 ; 1 : 356-359 – reference: 7) DeHertogh DA, Rossof AH, Harris AA, et al : Prednisone management of granulomatous mastitis. N Engl J Med 1980 ; 303 : 799-800 – reference: 9) Mathelin C, Riegel P, Chenard MP, et al : Granulomatous mastitis and corynebacteria : clinical and pathologic correlations. Breast J 2005 ; 11 : 357 – reference: 2) Paviour S, Musaad S, Roberts S, et al : Corynebacterium species isolated from patients with mastitis. Clin Infect Dis 2002 ; 35 : 1434-1440 – reference: 8) 加藤久美子,神尾麻紀子,野木裕子他:肉芽腫性乳腺炎の3例―ステロイド治療の検討―.乳癌の臨 2010;25:593-598 – reference: 11) 大楠清文:Corynebacterium kroppenstedtii. Med Technol 2011;39:1072-1078 |
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