Signal Transducers and Activators of Transcription 3 Signaling Pathway

• Published in: Inflammatory bowel diseases Vol. 11; no. 2; pp. 91 - 98
• Main Authors: Musso, Alessandro, Dentelli, Patrizia, Carlino, Alessandra, Chiusa, Luigi, Repici, Alessandro, Sturm, Andreas, Fiocchi, Claudio, Rizzetto, Mario, Pegoraro, Luigi, Sategna-Guidetti, Carla, Brizzi, Maria Felice
• Format: Journal Article
• Language: English; Japanese
• Published: Oxford, UK Oxford University Press 01.02.2005
• Subjects: celiac disease; intestinal inflammation; signal transduction; inflammatory bowel disease; STAT3

Crohn's disease (CD) and ulcerative colitis (UC), the two major forms of chronic inflammatory bowel disease (IBD), are characterized by mucosal immune cell activation that is driven by a cytokine imbalance. Several cytokines involved in IBD act through the activation of the signal transducers a...