Eicosapentaenoic acid inhibits tube formation of vascular endothelial cellsin vitro

• Published in: Lipids Vol. 26; no. 4; pp. 271 - 276
• Main Authors: Kanayasu, Toshie, Morita, Ikuo, Nakao‐Hayashi, Junko, Asuwa, Noriko, Fujisawa, Chiho, Ishii, Toshiharu, Ito, Hideki, Murota, Sei‐itsu
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer‐Verlag 01.04.1991

We previously have described a quantitative angiogenesisin vitro model, in which endothelial cells are cultured between two layers of type I collagen gel and become organized into tube‐like structures. Using this model, the effect of eicosapentaenoic acid (20∶5n−3) on tube formation was investigated...