OR-56: Cytochrome P450 products of arachidonate contribute to the differential control of renal cortical and medullary perfusion

• Published in: American journal of hypertension Vol. 16; no. S1; p. 26A
• Main Authors: Rajapakse, Niwanthi W., Falck, John R., Oliver, Jeremy J., Evans, Roger G.
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.05.2003
• Subjects: Cytochrome P450; Renal cortical blood flow; Renal medullary blood flow

Cytochrome P450 (CYP450) metabolises arachidonate to 19- and 20-hydroxyeicosatetraenoic acid (19/20-HETE) and epoxyeicosatrienoic acids (EETs) via the ω-hydroxylase and epoxygenase pathways, respectively. We hypothesised that regionally-selective release of these metabolites contributes to the hormo...