NAT10 regulates p53 activation through acetylating p53 at K120 and ubiquitinating Mdm2 - Liu, Xiaofeng; Tan, Yuqin; Zhang, Chunfeng; Zhang, Ying; Zhang, Liangliang; Ren, Pengwei; Deng, Hongkui; Luo, Jianyuan; Ke, Yang; Du, Xiaojuan (EMBO reports, 2016)
Keywords: Acetylation; Active Transport, Cell Nucleus; Apoptosis; Cell cycle; Cell Nucleus - metabolism; Colorectal cancer; Colorectal Neoplasms - metabolism; Deoxyribonucleic acid; DNA; DNA Damage; E3 ligase; EMBO31; EMBO37; Genomes; HCT116 Cells; HEK293 Cells; Humans; Mdm2; N-Terminal Acetyltransferase E - genetics; N-Terminal Acetyltransferase E - metabolism; N-Terminal Acetyltransferases; NAT10; p53; Protein Binding; Protein Stability; Proteolysis; Proto-Oncogene Proteins c-mdm2 - metabolism; Tumor Suppressor Protein p53 - metabolism; Ubiquitination; acetylation; Mdm2; NAT10; E3 ligase; p53