11.7 A multimodality CMOS sensor array for cell-based assay and drug screening

• Published in: 2015 IEEE International Solid State Circuits Conference (ISSCC) pp. 1 - 3
• Main Authors: Jong Seok Park, Taiyun Chi, Butts, Jessica, Hookway, Tracy, McDevitt, Todd, Hua Wang
• Format: Conference Proceeding Journal Article
• Language: English
• Published: IEEE 01.02.2015
• Subjects: Assaying; Biochemistry; Cascades; Cellular; CMOS integrated circuits; Drugs; Impedance; Optical sensors; Screening; Sensor arrays; Sensors; Stimuli; Temperature sensors

Cell-based assays are powerful tools to characterize cell- or tissue-specific physiological behaviors under external biochemical stimuli. External biochemical stimuli trigger endogenous cellular mechanisms that produce a cascade of physiological changes, resulting in easily measurable signals. Cell-...