NTR1 is required for transcription elongation checkpoints at alternative exons in Arabidopsis

• Published in: The EMBO journal Vol. 34; no. 4; pp. 544 - 558
• Main Authors: Dolata, Jakub, Guo, Yanwu, Kołowerzo, Agnieszka, Smoliński, Dariusz, Brzyżek, Grzegorz, Jarmołowski, Artur, Świeżewski, Szymon
• Format: Journal Article
• Language: English
• Published: London Blackwell Publishing Ltd 12.02.2015; Nature Publishing Group UK; Springer Nature B.V; BlackWell Publishing Ltd
• Subjects: alternative splicing; Arabidopsis - genetics; Arabidopsis - metabolism; Botany; elongation checkpoint; EMBO09; EMBO30; EMBO44; Exons - genetics; Genetics; Mutants; Mutation; Periplasmic Binding Proteins - genetics; Periplasmic Binding Proteins - metabolism; RNA polymerase; RNA Splice Sites - genetics; Site selection; transcription; Transcription factors; Transcription, Genetic - genetics; alternative splicing; transcription; elongation checkpoint

The interconnection between transcription and splicing is a subject of intense study. We report that Arabidopsis homologue of spliceosome disassembly factor NTR1 is required for correct expression and splicing of DOG1 , a regulator of seed dormancy. Global splicing analysis in atntr1 mutants reveale...