Analysis of the population genetic structure of Hb D-Los Angeles [β121 (GH4) Glu→Gln GAA→CAA] in Denizli, Turkey; genetic diversity, historical demography and estimation of the mutation rates based on haplotype variation

• Published in: American journal of human biology Vol. 28; no. 4; pp. 476 - 483
• Main Authors: Ozturk, Onur, Arikan, Sanem, Atalay, Ayfer, Atalay, Erol O.
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.07.2016
• Subjects: Demography; Genetic Variation; Haplotypes - genetics; Hemoglobins, Abnormal - genetics; Humans; Mutation Rate; Turkey; MED, Turkey; MED; ISW, India

Objective Understanding the genetic origin of the Hb D‐Los Angeles hemoglobin may elucidate population interactions such as movements, migrations, and environmental effects on mutation mechanisms in human biology throughout history. Our study aimed to understand the genetic origin of Hb D‐Los Angele...