Tigecycline pharmacokinetics, tolerability, safety, and effect on intestinal microflora in healthy Japanese male subjects - Yamashita, Noriaki; Matschke, Kyle; Gandhi, Ashesh; Korth-Bradley, Joan (Journal of clinical pharmacology, 2014)
Keywords: Adult; Anti-Bacterial Agents - adverse effects; Anti-Bacterial Agents - pharmacokinetics; Anti-Bacterial Agents - pharmacology; Asian Continental Ancestry Group; Bacterial Load; Bacteroides - isolation & purification; Double-Blind Method; Enterobacteriaceae - isolation & purification; Enterococcus - isolation & purification; Feces - chemistry; Healthy Volunteers; Humans; Intestines - microbiology; Male; Microbiota - drug effects; Middle Aged; Minocycline - adverse effects; Minocycline - analogs & derivatives; Minocycline - pharmacokinetics; Minocycline - pharmacology; Nausea - chemically induced; Vomiting - chemically induced; Young Adult; pharmacokinetics; healthy subjects; Japanese; tigecycline