Pharmacokinetics and pharmacodynamics of intravenous dexmedetomidine in healthy Korean subjects - Lee, S.; Kim, B.-H.; Lim, K.; Stalker, D.; Wisemandle, W.; Shin, S.-G.; Jang, I.-J.; Yu, K.-S. (Journal of clinical pharmacy and therapeutics, 2012)
Keywords: Adrenergic alpha-2 Receptor Agonists - administration & dosage; Adrenergic alpha-2 Receptor Agonists - pharmacokinetics; Adrenergic alpha-2 Receptor Agonists - pharmacology; Adult; Area Under Curve; Biological and medical sciences; dexmedetomidine; Dexmedetomidine - administration & dosage; Dexmedetomidine - pharmacokinetics; Dexmedetomidine - pharmacology; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Hypnotics and Sedatives - administration & dosage; Hypnotics and Sedatives - pharmacokinetics; Hypnotics and Sedatives - pharmacology; Infusions, Intravenous; Korean; Male; Medical sciences; Models, Biological; Nonlinear Dynamics; pharmacodynamics; pharmacokinetics; Pharmacology. Drug treatments; population pharmacokinetics; Republic of Korea; Tissue Distribution; Asia; Korea; Republic of Korea; α2-Adrenergic receptor; Human; Population pharmacokinetics; Pharmacokinetic pharmacodynamic relationship; Agonist; Pharmacodynamics; Intravenous administration; Healthy subject; Korean; Biological activity; Dexmedetomidine; pharmacokinetics; α-Adrenergic receptor agonist