Traumatic scratch injury in astrocytes triggers calcium influx to activate the JNK/c-Jun/AP-1 pathway and switch on GFAP expression - Gao, Kai; Wang, Chen Ran; Jiang, Feng; Wong, Ann Yuen Kwan; Su, Na; Jiang, Jiao Hua; Chai, Rui Chao; Vatcher, Greg; Teng, Junlin; Chen, Jianguo; Jiang, Yu-Wu; Yu, Albert Cheung Hoi (Glia, 2013)
Keywords: Activator protein 1; Animals; Astrocytes - cytology; Astrocytes - metabolism; astrogliosis; Brain damage; Calcium; Calcium - metabolism; Calcium Signaling - genetics; calcium wave; Cells, Cultured; Cerebral Cortex - cytology; Cerebral Cortex - metabolism; Genes, jun - physiology; glial fibrillary acidic protein; Glial Fibrillary Acidic Protein - metabolism; glial scar; Gliosis - genetics; Gliosis - metabolism; JNK; MAP Kinase Signaling System - physiology; Mice; Mice, Inbred ICR; Transcription Factor AP-1 - genetics; Transcription Factor AP-1 - metabolism; Transcriptional Activation; calcium wave; astrogliosis; glial scar; glial fibrillary acidic protein; JNK