Aberrant astrocytes impair vascular reactivity in Huntington disease - Hsiao, Han-Yun; Chen, Yu-Chen; Huang, Chien-Hsiang; Chen, Chiao-Chi; Hsu, Yi-Hua; Chen, Hui-Mei; Chiu, Feng-Lan; Kuo, Hung-Chih; Chang, Chen; Chern, Yijuang (Annals of neurology, 2015)
Keywords: Adult; Aged; Animals; Astrocytes - metabolism; Astrocytes - pathology; Blood Vessels - metabolism; Blood Vessels - pathology; Blood Vessels - physiopathology; Brain; Brain - blood supply; Brain - metabolism; Brain - pathology; Cells, Cultured; Female; Humans; Huntingtin Protein; Huntington Disease - metabolism; Huntington Disease - pathology; Huntington Disease - physiopathology; Induced Pluripotent Stem Cells - metabolism; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Male; Mice; Mice, Transgenic; Middle Aged; Nerve Tissue Proteins - metabolism; Neurons - metabolism; NMR; Nuclear magnetic resonance; Nuclear Proteins - metabolism; Pericytes - pathology; Rodents; Vascular endothelial growth factor; Vascular Endothelial Growth Factor A - metabolism