Pharmacokinetics of a Transdermal Fentanyl Solution in Suffolk Sheep (Ovis aries)

• Published in: Journal of the American Association for Laboratory Animal Science Vol. 56; no. 5; pp. 550 - 557
• Main Authors: Jen, Kimberly Y, Dyson, Melissa C, Lester, Patrick A, Nemzek, Jean A
• Format: Journal Article
• Language: English
• Published: United States American Association for Laboratory Animal Science 01.09.2017
• Subjects: Anesthesia

Sheep used as surgical models require appropriate pain management, and the commonly used transdermal fentanyl patches require a long predosing period to achieve adequate plasma concentrations. The aim of this study was to assess the pharmacokinetic parameters of an FDA-approved transdermal fentanyl...