Balance between von Willebrand factor and ADAMTS13 following major partial hepatectomy

• Published in: British journal of surgery Vol. 103; no. 6; pp. 735 - 743
• Main Authors: Groeneveld, D. J., Alkozai, E. M., Adelmeijer, J., Porte, R. J., Lisman, T.
• Format: Journal Article
• Language: English
• Published: Chichester, UK John Wiley & Sons, Ltd 01.05.2016; Oxford University Press
• Subjects: ADAMTS13 Protein - blood; Adult; Blood Coagulation; Female; Hepatectomy - adverse effects; Humans; Male; Middle Aged; Pancreaticoduodenectomy - adverse effects; Platelet Adhesiveness; Postoperative Period; von Willebrand Factor - metabolism

Background Conventional coagulation tests are frequently prolonged after liver surgery, suggesting a postoperative bleeding tendency. At the same time, thrombotic complications following partial hepatectomy (PH) are not uncommon. Little is known about changes in the platelet adhesive protein von Wil...