Miniaturization: The Clue to Clinical Application of the Artificial Placenta

• Published in: Artificial organs Vol. 38; no. 3; pp. 208 - 214
• Main Authors: Schoberer, Mark, Arens, Jutta, Erben, Aileen, Ophelders, Daan, Jellema, Reint K., Kramer, Boris W., Bruse, Jan L., Brouwer, Petra, Schmitz-Rode, Thomas, Steinseifer, Ulrich, Orlikowsky, Thorsten
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.03.2014; Wiley Subscription Services, Inc
• Subjects: Animals; Artificial Organs; Artificial placenta; Drug therapy; Equipment Design; Extracorporeal life support; Extracorporeal Membrane Oxygenation - instrumentation; Female; Humans; Infant, Premature; Interventional lung assist; Miniaturization; Models, Animal; Neonatal respiratory failure; Placenta; Pregnancy; Respiratory Insufficiency - therapy; Sheep; Surgical apparatus & instruments; Artificial placenta; Neonatal respiratory failure; Interventional lung assist; Extracorporeal life support

The artificial placenta as a fascinating treatment alternative for neonatal lung failure has been the subject of clinical research for over 50 years. Pumpless systems have been in use since 1986. However, inappropriate dimensioning of commercially available oxygenators has wasted some of the theoret...