Highly Automated QT Measurement Techniques in 7 Thorough QT Studies Implemented under ICH E14 Guidelines - Couderc, Jean-Philippe; Garnett, Christine; Li, Mike; Handzel, Robert; McNitt, Scott; Xia, Xiajuan; Polonsky, Slava; Zareba, Wojciech (Annals of noninvasive electrocardiology, 2011)
Keywords: Anti-Infective Agents - pharmacology; Aza Compounds - pharmacology; Cardiotoxins; drug cardiotoxicity; Drug Evaluation, Preclinical; drug safety; electrocardiogram; Electrocardiography; Female; Fluoroquinolones; Guidelines as Topic; Heart Conduction System - drug effects; Humans; Long QT Syndrome - chemically induced; Male; Models, Biological; Moxifloxacin; Neuromuscular Nondepolarizing Agents - administration & dosage; Original; QT interval; Quinolines - pharmacology; Sex Factors; thorough QT study