The association between BANK1 and TNFAIP3 gene polymorphisms and systemic lupus erythematosus: a meta-analysis

• Published in: International journal of immunogenetics Vol. 38; no. 2; pp. 151 - 159
• Main Authors: Fan, Y., Tao, J.-H., Zhang, L.-P., Li, L.-H., Ye, D.-Q.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.04.2011
• Subjects: Adaptor Proteins, Signal Transducing - genetics; Alleles; Apoptosis; Calcium (intracellular); Calcium mobilization; DNA-Binding Proteins; Enzymes; Gene polymorphism; Genetic Heterogeneity; Genetic Predisposition to Disease; Humans; Intracellular Signaling Peptides and Proteins - genetics; Lupus Erythematosus, Systemic - genetics; Membrane Proteins - genetics; NF- Kappa B protein; Nuclear Proteins - genetics; Odds Ratio; Polymorphism, Single Nucleotide - genetics; Replication; Reviews; Risk Factors; scaffolds; Single-nucleotide polymorphism; Systemic lupus erythematosus; Tumor necrosis factor; Tumor Necrosis Factor alpha-Induced Protein 3; Zinc finger proteins

Summary The past decade has witnessed hundreds of reports declaring or not being able to replicable genetic association with systemic lupus erythematosus (SLE) susceptibility. BANK1 is a gene that encodes a B‐cell‐specific scaffold protein and its activation can affect B‐cell‐receptor‐induced calciu...