Clinical and metabolic response to probiotic supplementation in patients with rheumatoid arthritis: a randomized, double-blind, placebo-controlled trial

• Published in: International journal of rheumatic diseases Vol. 19; no. 9; pp. 869 - 879
• Main Authors: Zamani, Batol, Golkar, Hamid R., Farshbaf, Shima, Emadi-Baygi, Modjtaba, Tajabadi-Ebrahimi, Maryam, Jafari, Parvaneh, Akhavan, Reyhaneh, Taghizadeh, Mohsen, Memarzadeh, Mohammad R., Asemi, Zatollah
• Format: Journal Article
• Language: English
• Published: England Blackwell Publishing Ltd 01.09.2016
• Subjects: Adult; Aged; Arthritis, Rheumatoid - blood; Arthritis, Rheumatoid - diagnosis; Arthritis, Rheumatoid - microbiology; Arthritis, Rheumatoid - therapy; Bifidobacterium bifidum; Bifidobacterium bifidum - physiology; Biomarkers - blood; Blood Glucose - metabolism; C-Reactive Protein - metabolism; Cholesterol, LDL - blood; Double-Blind Method; Female; Gastrointestinal Microbiome; Humans; Insulin - blood; Intestines - microbiology; Iran; Lacticaseibacillus casei - physiology; Lactobacillus acidophilus; Lactobacillus acidophilus - physiology; Lactobacillus casei; Male; metabolic profiles; Middle Aged; probiotic; Probiotics - administration & dosage; Probiotics - adverse effects; rheumatoid arthritis; supplementation; Time Factors; Treatment Outcome; supplementation; probiotic; metabolic profiles; rheumatoid arthritis

Objective This study was performed to determine the effects of probiotic supplementation on clinical and metabolic status of patients with rheumatoid arthritis (RA). Methods Sixty patients with RA aged 25–70 years were assigned into two groups to receive either probiotic capsules (n = 30) or placebo...