Effect of food, an antacid, and the H2 antagonist ranitidine on the absorption of BAY 59-7939 (rivaroxaban), an oral, direct factor Xa inhibitor, in healthy subjects - Kubitza, Dagmar; Becka, Michael; Zuehlsdorf, Michael; Mueck, Wolfgang (Journal of clinical pharmacology, 2006)
Keywords: Adult; Aluminum Hydroxide - pharmacology; Antacids - pharmacology; Cross-Over Studies; Dietary Carbohydrates - pharmacology; Dietary Fats - pharmacology; Drug Combinations; Drug Interactions; Factor Xa Inhibitors; Fasting - metabolism; Food-Drug Interactions; Histamine H2 Antagonists - pharmacology; Humans; Intestinal Absorption - drug effects; Magnesium Hydroxide - pharmacology; Male; Morpholines - adverse effects; Morpholines - blood; Morpholines - pharmacokinetics; Morpholines - pharmacology; Prothrombin Time; Ranitidine - pharmacology; Rivaroxaban; Thiophenes - adverse effects; Thiophenes - blood; Thiophenes - pharmacokinetics; Thiophenes - pharmacology