In-vivo quantification of lactate using Near Infrared reflectance spectroscopy

• Published in: 2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) Vol. 2021; pp. 7024 - 7027
• Main Authors: Baishya, N, Mamouei, M, Budidha, K, Qassem, M, Vadgama, P, Kyriacou, P A
• Format: Conference Proceeding Journal Article
• Language: English
• Published: United States IEEE 01.11.2021
• Subjects: Biosensors; Critical Care; Humans; Lactate; Lactic Acid; Linear regression; Near Infrared; Protocols; Reflectivity; Sepsis - diagnosis; Spectroscopy; Spectroscopy, Near-Infrared; Translational research; Wavelength measurement

Elevated lactate levels in blood (hyperlactatemia) are indications of hypoperfusion or sepsis in critical care conditions. Quantification and monitoring of this important marker is performed using intermittent blood sampling, which fails to provide a complete scenario to aid clinicians in diagnosis....