Facial skin-lightening benefits of the tetrapeptide Pro-Lys-Glu-Lys on subjects with skin types V-VI living in South Africa

• Published in: Journal of cosmetic dermatology Vol. 10; no. 3; pp. 217 - 223
• Main Authors: Farwick, Mike, Maczkiewitz, Ursula, Lersch, Peter, Summers, Beverley, Rawlings, Anthony V.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.09.2011
• Subjects: Adult; Dermatologic Agents - therapeutic use; Double-Blind Method; Face; Female; Glutamic Acid - administration & dosage; Humans; Lysine - administration & dosage; Melanosis - drug therapy; Middle Aged; Oligopeptides - therapeutic use; peptide; photoaging; Proline - administration & dosage; proline attached to its N-terminus; proopiomelanocortin; Skin Pigmentation - drug effects; skin-lightening; South Africa; Treatment Outcome; α-melanocyte-stimulating hormone; South Africa
• ISSN: 1473-2130; 1473-2165; 1473-2165
• DOI: 10.1111/j.1473-2165.2011.00569.x

Summary Background  Irregular skin pigmentation may be a substantial contributor to the signs of aging and to a person’s lack of psychological well‐being. Although a large number of skin‐lightening agents are available, the opportunity exists to identify more efficacious agents, agents that target a...