An evaluation of the emergence of drug resistant virus for HIV/AIDS drug treatments

• Published in: 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) Vol. 2015; pp. 3258 - 3261
• Main Author: Chang, Hyuk-Jun
• Format: Conference Proceeding Journal Article
• Language: English
• Published: United States IEEE 01.08.2015
• Subjects: Anti-HIV Agents - administration & dosage; Anti-HIV Agents - therapeutic use; Computer Simulation; Dose-Response Relationship, Drug; Drug Resistance, Viral - genetics; Drugs; HIV Infections - drug therapy; HIV Infections - virology; Human immunodeficiency virus; Humans; Immune system; Mathematical model; Mutation; Strain; Switches

HIV/AIDS drug treatment, such as highly active anti-retroviral therapy (HAART), often fails due to the emergence of drug resistant species. In this paper we investigate a new estimation method for the possibility of emergence of drug resistant mutation. To the best knowledge of the author this work...