Platelet inhibitory activity and pharmacokinetics of prasugrel (CS-747) a novel thienopyridine P2Y12 inhibitor: A single ascending dose study in healthy humans - Asai, Fumitoshi; Jakubowski, Joseph A.; Naganuma, Hideo; Brandt, John T.; Matsushima, Nobuko; Hirota, Takashi; Freestone, Stephen; Winters, Kenneth J. (Platelets (Edinburgh), 2006)
Keywords: Adenosine Diphosphate - pharmacology; Administration, Oral; Adolescent; Adult; CS-747; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; phase 1; Piperazines - administration & dosage; Piperazines - blood; Piperazines - pharmacokinetics; Platelet Aggregation - drug effects; Platelet Aggregation Inhibitors - administration & dosage; Platelet Aggregation Inhibitors - blood; Platelet Aggregation Inhibitors - pharmacokinetics; platelets; Prasugrel; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; thienopyridine; Thiophenes - administration & dosage; Thiophenes - blood; Thiophenes - pharmacokinetics; Time Factors