18F-Fluorodeoxyglycosylamines: Maillard reaction of 18F-fluorodeoxyglucose with biological amines

• Published in: Journal of labelled compounds & radiopharmaceuticals Vol. 57; no. 2; pp. 86 - 91
• Main Authors: Baranwal, Aparna, Patel, Himika H., Mukherjee, Jogeshwar
• Format: Journal Article
• Language: English
• Published: England Blackwell Publishing Ltd 01.02.2014; Wiley Subscription Services, Inc
• Subjects: 18F-FDG; Alzheimer Disease - diagnostic imaging; Amyloid beta-Peptides - metabolism; Benzothiazoles - chemistry; Biogenic Amines - chemical synthesis; Biogenic Amines - pharmacology; Case-Control Studies; Fluorodeoxyglucose F18 - chemistry; Humans; Maillard Reaction; Protein Binding; Pyrrolidines - chemistry; quasi-Amadori product; Radionuclide Imaging; Maillard reaction; quasi-Amadori product; 18F-FDG

The Maillard reaction of sugars and amines resulting in the formation of glycosylamines and Amadori products is of biological significance, for drug delivery, role in central nervous system, and other potential applications. We have examined the interaction of 18F‐fluorodeoxyglucose (18F‐FDG) with b...