N,N,5-trimethyl-1H-[1]benzothiopyrano[4,3,2-cd]-indazole-1-ethanamine - A novel heterocycle

Treatment of thioxanthenone 6 with N-(2-dimethylaminoethyl)hydrazine led to the benzothiopyranoindazole 3, a novel heterocycle, along with the expected compound 8.

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Bibliographic Details
Published inJournal of heterocyclic chemistry Vol. 34; no. 5; pp. 1637 - 1638
Main Authors Krapcho, AP, Haydar, SN
Format Journal Article
LanguageEnglish
Published ODESSA HETERO CORPORATION 01.09.1997
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
BENZOTHIOPYRANOINDAZOLES
DNA
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Abstract Treatment of thioxanthenone 6 with N-(2-dimethylaminoethyl)hydrazine led to the benzothiopyranoindazole 3, a novel heterocycle, along with the expected compound 8.
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Author Haydar, SN
Krapcho, AP
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Keywords BENZOTHIOPYRANOINDAZOLES
DNA
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References BEYLIN, VG (WOS:A1991FM59100061) 1991; 28
ARCHER, S (WOS:A1952UB42800017) 1952; 74
JAHANGIR, M (WOS:A1977ED29000078) 1977; 29
SHOWALTER, HDH (WOS:A1988P416200009) 1988; 31
FRY, DW (WOS:A1988L825400012) 1988; 33
BAILLY, C (WOS:A1993LG87000009) 1993; 32
MAUSS, H (WOS:A1948UK99300003) 1948; 81
References_xml – volume: 33
  start-page: 84
  year: 1988
  ident: WOS:A1988L825400012
  article-title: BIOCHEMICAL PHARMACOLOGY AND DNA-DRUG INTERACTIONS BY CL-958, A NEW ANTITUMOR INTERCALATOR DERIVED FROM A SERIES OF SUBSTITUTED 2H-[1]BENZOTHIOPYRANO[4,3,2-CD]INDAZOLES
  publication-title: MOLECULAR PHARMACOLOGY
  contributor:
    fullname: FRY, DW
– volume: 81
  start-page: 19
  year: 1948
  ident: WOS:A1948UK99300003
  article-title: UBER BASISCH SUBSTITUIERTE XANTHON-ABKOMMLINGE UND THIOXANTHON-ABKOMMLINGE - MIRACIL, EIN NEUES CHEMOTHERAPEUTICUM
  publication-title: CHEMISCHE BERICHTE-RECUEIL
  contributor:
    fullname: MAUSS, H
– volume: 31
  start-page: 1527
  year: 1988
  ident: WOS:A1988P416200009
  article-title: BENZOTHIOPYRANOINDAZOLES, A NEW CLASS OF CHROMOPHORE MODIFIED ANTHRACENEDIONE ANTICANCER AGENTS - SYNTHESIS AND ACTIVITY AGAINST MURINE LEUKEMIAS
  publication-title: JOURNAL OF MEDICINAL CHEMISTRY
  contributor:
    fullname: SHOWALTER, HDH
– volume: 28
  start-page: 517
  year: 1991
  ident: WOS:A1991FM59100061
  article-title: AN IMPROVED SYNTHESIS OF ANTICANCER BENZOTHIOPYRANOINDAZOLES - AN EFFICIENT LARGE-SCALE BETA-AMINOETHYLATION PROCEDURE
  publication-title: JOURNAL OF HETEROCYCLIC CHEMISTRY
  contributor:
    fullname: BEYLIN, VG
– volume: 74
  start-page: 4296
  year: 1952
  ident: WOS:A1952UB42800017
  article-title: THE PREPARATION OF SOME 1-ALKYLAMINOTHIAXANTHONES AND DIALKYLAMINOALKYLAMINOTHIAXANTHONES
  publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
  contributor:
    fullname: ARCHER, S
– volume: 32
  start-page: 5985
  year: 1993
  ident: WOS:A1993LG87000009
  article-title: PREFERENTIAL INTERCALATION AT AT SEQUENCES IN DNA BY LUCANTHONE, HYCANTHONE, AND INDAZOLE ANALOGS - A FOOTPRINTING STUDY
  publication-title: BIOCHEMISTRY
  contributor:
    fullname: BAILLY, C
– volume: 29
  start-page: P78
  year: 1977
  ident: WOS:A1977ED29000078
  article-title: STRONG NONCOVALENT BINDING OF HYCANTHONE TO DNA
  publication-title: JOURNAL OF PHARMACY AND PHARMACOLOGY
  contributor:
    fullname: JAHANGIR, M
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Snippet Treatment of thioxanthenone 6 with N-(2-dimethylaminoethyl)hydrazine led to the benzothiopyranoindazole 3, a novel heterocycle, along with the expected...
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Chemistry, Organic
Physical Sciences
Science & Technology
Title N,N,5-trimethyl-1H-[1]benzothiopyrano[4,3,2-cd]-indazole-1-ethanamine - A novel heterocycle
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